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anti-Fermitin Family Member 2 (FERMT2) Antibodies

Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Additionally we are shipping FERMT2 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FERMT2 218952 Q8CIB5
FERMT2 10979 Q96AC1
FERMT2 289992  
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Top anti-FERMT2 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: FERMT2  Sample Tissue: HT1080 Whole Cell lysates  Antibody Dilution: 1.0 µg/mL FERMT2 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB FERMT2 Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the FERMT2 antibody detected the FERMT2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot analysis of PLEKHC1 expression in transfected 293T cell line by PLEKHC1 monoclonal antibody (M09), clone 2G11.Lane 1: PLEKHC1 transfected lysate(77.9 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of monoclonal antibody to FERMT2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, IP, WB Anti-FERMT2 mouse monoclonal antibody (ABIN2453039) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FERMT2 (RC205727). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FERMT2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FERMT2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IP, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FERMT2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FERMT2. Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-FERMT2mouse monoclonal antibody. (ABIN2452469, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IP, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FERMT2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FERMT2. Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-FERMT2mouse monoclonal antibody. (ABIN2452653, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), IP, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

FERMT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FERMT2 Antibodies

  1. Human Monoclonal FERMT2 Primary Antibody for IF, ELISA - ABIN564761 : Dowling, Vreede, Kim, Golden, Feldman: Kindlin-2 is required for myocyte elongation and is essential for myogenesis. in BMC cell biology 2008 (PubMed)

More Antibodies against FERMT2 Interaction Partners

Mouse (Murine) Fermitin Family Member 2 (FERMT2) interaction partners

  1. These findings show that talin and kindlin cooperatively activate integrins leading to fibronectin (show FN1 Antibodies) binding and adhesion.

  2. These studies uncover a previously unrecognized function for Kindlin-2 and a mechanism for regulation of the chondrocyte differentiation programme and chondrogenesis.

  3. Taken together, our study suggests the suppressive roles of Kindlin-2 in the pathogenesis of colorectal carcinoma

  4. Data suggest that kindlin-2 (Kind2/Fermt2) interacts with actin alpha 2 (Actn2 (show ACTN2 Antibodies)) and integrin beta 1 (Itgb1 (show ITGB1 Antibodies)) and co-localizes to cardiac sarcomere at Z-disc; knockdown of Kind2 leads to dissociation of Actn2 (show ACTN2 Antibodies) and Itgb1 (show ITGB1 Antibodies).

  5. beta3/kindlin-2 interaction promotes outside-in alphaVbeta3 signaling selectively, with biological consequences in vivo [kindlin-2]

  6. kindlin-2 tyrosine phosphorylation and interaction with Src serve as a regulatable switch downstream of focal adhesion kinase in the integrin outside-in signaling circuit controlling cell migration and proliferation

  7. kindlin-2, through activating Ras and the downstream ERK1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) signaling pathways, plays an important role in regulating renal tubular epithelial-to-mesenchymal transition

  8. C-terminal LIM (show PDLIM5 Antibodies) domains of migfilin (show FBLIM1 Antibodies) dictate its focal adhesion localization, and these domains mediate an interaction with kindlin in vitro and in cells, demonstrating that kindlin is important for normal migfilin (show FBLIM1 Antibodies) dynamics.

  9. kindlin-2 regulates trafficking of endothelial cell surface enzymes that control platelet responses and hemostasis.

  10. Kindlin-2 mediates activation of TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling and renal fibrosis.

Human Fermitin Family Member 2 (FERMT2) interaction partners

  1. The F0 domain of K2 binds actin.

  2. data indicate that kindlin-2 promotes the invasiveness of prostate cancer cells largely through NF-kappaB (show NFKB1 Antibodies)-dependent upregulation of MMP-9 (show MMP9 Antibodies) and MMP-2 (show MMP2 Antibodies)

  3. High kindlin-2 expression is associated with esophageal squamous cell carcinoma.

  4. our findings suggested that Kindlin-2 was highly expressed in hepatocellular carcinoma tissues and was closely related to clinical progression. Kindlin-2 protein could be a potential biomarker for predicting poor prognosis of HCC (show FAM126A Antibodies) patients after surgery.

  5. findings suggest that Src (show SRC Antibodies), Kindlin-2 and Migfilin (show FBLIM1 Antibodies) together constitute a positive feedback loop that controls Src (show SRC Antibodies) activity and regulates integrin-mediated cellular func

  6. Data indicate that Kindlin-2 mRNA levels in adult is highly expressed in mesoderm-derived organs.

  7. A major ILK (show ILK Antibodies) binding site in the kindlin-2 FERM domain for regulating cell adhesion has been mapped.

  8. the first evidence that interaction between the integrin beta1 cytoplasmic tail and kindlin-2, a member of a family of adapters implicated in human disease pathogenesis, is mainly governed by the beta1 C-terminal carboxylate moiety

  9. Kindlin-2 was highly expressed in the peritumoral stroma of pancreatic ductal adenocarcinomas. Stromal kindlin-2 expression was related to nodal metastasis (P = 0.03).

  10. Kindlin-2 mediates activation of TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling and renal fibrosis.

FERMT2 Antigen Profile

Protein Summary

Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites (By similarity).

Gene names and symbols associated with FERMT2

  • fermitin family homolog 2 (Drosophila) (Fermt2) antibody
  • fermitin family member 2 (FERMT2) antibody
  • fermitin family member 2 (Fermt2) antibody
  • AA960555 antibody
  • KIND2 antibody
  • Kindlin-2 antibody
  • mig-2 antibody
  • MIG2 antibody
  • PLEKHC1 antibody
  • UNC112 antibody
  • UNC112B antibody

Protein level used designations for FERMT2

fermitin family homolog 2 , mitogen inducible 2 , pleckstrin homology domain containing, family C (with FERM domain) member 1 , pleckstrin homology domain-containing family C member 1 , PH domain-containing family C member 1 , kindlin 2 , kindlin-2 , mitogen inducible gene 2 protein , mitogen-inducible gene 2 protein , pleckstrin homology domain containing, family C member 1

GENE ID SPECIES
218952 Mus musculus
10979 Homo sapiens
490693 Canis lupus familiaris
289992 Rattus norvegicus
Selected quality suppliers for anti-FERMT2 (FERMT2) Antibodies
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