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anti-Fibrinogen alpha Chain (FGA) Antibodies

The protein encoded by FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen alpha Chain Kits (42) and Fibrinogen alpha Chain Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FGA 2243 P02671
FGA 14161  
FGA 361969  
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Top anti-Fibrinogen alpha Chain Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-FGA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-FGA Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of FGA Antibody (N-term) (ABIN390830) in Jurkat cell line lysates (35 µg/lane). FGA (arrow) was detected using the purified polyclonal antibody. FGA Antibody (N-term) (ABIN390830) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB Fibrinogen Alpha antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Squamous epithelial cells (arrows) in Human Skin. Magnification is at 400X Fibrinogen Alpha antibody used at 5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$437.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated WB FGA Antibody (N-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the FGA antibody detected the FGA protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB FGA Antibody (N-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the FGA(N-term) antibody detected the FGA(N-term) protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

FGA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Fibrinogen alpha Chain Antibodies

  1. Human Polyclonal FGA Primary Antibody for WB - ABIN2776978 : Jood, Danielson, Ladenvall, Blomstrand, Jern: Fibrinogen gene variation and ischemic stroke. in Journal of thrombosis and haemostasis : JTH 2008 (PubMed)
    Show all 2 references for ABIN2776978

  2. Human Polyclonal FGA Primary Antibody for IF, IHC (p) - ABIN390830 : Thomas, Wheeless, Stack, Johnson: Human mast cell tryptase fibrinogenolysis: kinetics, anticoagulation mechanism, and cell adhesion disruption. in Biochemistry 1998 (PubMed)

  3. Human Polyclonal FGA Primary Antibody for IHC, WB - ABIN630126 : Matsumoto, Matsuura, Aoki, Maehashi, Iwamoto, Ohkawa, Yoshida, Yanaga, Takada: An efficient system for secretory production of fibrinogen using a hepatocellular carcinoma cell line. in Hepatology research : the official journal of the Japan Society of Hepatology 2014 (PubMed)

  4. Cow (Bovine) Polyclonal FGA Primary Antibody for IHC, WB - ABIN2776977 : Smolarczyk, Boncela, Szymanski, Gils, Cierniewski: Fibrinogen contains cryptic PAI-1 binding sites that are exposed on binding to solid surfaces or limited proteolysis. in Arteriosclerosis, thrombosis, and vascular biology 2005 (PubMed)

More Antibodies against Fibrinogen alpha Chain Interaction Partners

Human Fibrinogen alpha Chain (FGA) interaction partners

  1. Neutrophilic asthma patients and eosinophilic asthma patients had increased fibrinogen compared to controls.

  2. To novel fibrinogen mutations have been identified (Aa17GlyalphaCys and Aa381SeralphaPhe) that cosegregate with dysfibrinogenemia in seven family members of a Chinese pedigree.

  3. The study reports two novel mutations detected in the FGA and FGB (show FGB Antibodies) genes in two patients with inherited hypofibrinogenemia.

  4. Nutrient overload-induced up-regulation of all three fibrinogen component subunits of the coagulation cascade provides a possible mechanism to explain the excess cardiovascular disease mortality observed in non-alcoholic fatty liver disease patients.

  5. An analysis of the results obtained in this study and a critical review of previously published data indicate that gene polymorphisms in FGA and FGB (show FGB Antibodies) are not related to ischemic stroke in children

  6. Results support the idea that fibrinogen alphaC regions are involved in the thickening of fibrin fibers.

  7. The study identified a 5.9 kDa C-terminal fragment of the fibrinogen alpha chain as an early serum biomarker of fibrogenic processes in patients with liver disease.

  8. The Aalpha-Val360 related cross-sectionally to physiologic, radiologic, and symptomatic markers of disease severity of PiZZ alpha1-antitrypsin deficiency.

  9. Case Report: hepatocytes homozygous for a large FGA deletion can be genetically modified to restore Aalpha-chain protein expression and secrete a functional fibrinogen hexamer.

  10. High plasma D-dimer, fibrinogen, and platelet levels are associated with epithelial ovarian cancer independently of venous thromboembolism.

Cow (Bovine) Fibrinogen alpha Chain (FGA) interaction partners

  1. NMR solution structure of the bovine fibrinogen alphaC-domain fragment, including residues Aalpha374-538, reveals a type-I' beta-hairpin, restricted at the base by a C423-C453 disulfide linkage and a short turn preceding C423.

Mouse (Murine) Fibrinogen alpha Chain (FGA) interaction partners

  1. cellular fibrin uptake was diminished by elimination of CCR2-expressing cells.

  2. Mice expressing a mutant form of fibrinogen cannot support fibrin formation exhibit compromised antimicrobial host defense.

  3. Data indicate RU-505 as an effective inhibitor of the beta-amyloid (Abeta)-fibrinogen interaction.

  4. Fbg deficiency was associated with enhanced hepatic expression of the transcription factor early growth response-1 (show EGR1 Antibodies).

Pig (Porcine) Fibrinogen alpha Chain (FGA) interaction partners

  1. Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.

Fibrinogen alpha Chain (FGA) Antigen Profile

Protein Summary

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.

Gene names and symbols associated with FGA

  • fibrinogen alpha chain (FGA) antibody
  • fibrinogen alpha chain (Fga) antibody
  • Ac1873 antibody
  • ENSMUSG00000059807 antibody
  • Fba5e antibody
  • Fib antibody
  • Fib2 antibody

Protein level used designations for FGA

fibrinogen alpha chain , fibrinogen alpha chain-like , fibrinogen, A alpha polypeptide , fibrinogen A-alpha chain , fibrinogen, alpha polypeptide , carboxy-terminal region , fibrinogen A-alpha-chain , fibrinogen alpha subunit , fibrinogen alpha-E subunit , pre-fibrinogen alpha subunit

GENE ID SPECIES
100461464 Pongo abelii
100469401 Ailuropoda melanoleuca
100607544 Nomascus leucogenys
2243 Homo sapiens
522039 Bos taurus
14161 Mus musculus
475473 Canis lupus familiaris
100514666 Sus scrofa
361969 Rattus norvegicus
396307 Gallus gallus
100720646 Cavia porcellus
100069763 Equus caballus
100353616 Oryctolagus cuniculus
698244 Macaca mulatta
101102090 Ovis aries
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