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The protein encoded by FGB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen beta Chain Antibodies (113) and Fibrinogen beta Chain Proteins (19) and many more products for this protein.
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Prognostic impact of plasma fibrinogen levels in patients with esophageal squamous cell carcinoma
Data indicate that repeated measurement after five hours showed a statistical significant difference for the fractional synthesis rate of fibrinogen but not for albumin (show ALB ELISA Kits).
a tight cluster of alternating multiple splicing regulatory elements and U1 snRNA binding sites controls cryptic splice donor usage throughout the human fibrinogen Bbeta-chain gene (FGB) exon 7
The high preoperative peripheral serum fibrinogen level was related to poor survival in penile cancer patients, suggeting fibrinogen may serve as a powerful predictor of cancer specific survival (CSS (show CMAS ELISA Kits)) in penile cancer patients.
The plasma fibrinogen level was found to be a possible biomarker for clinical response to chemotherapy and postoperative metastasis or death in advanced breast cancer patients who received neoadjuvant chemotherapy
Data suggest that, in the binding of fibrin beta N-domains and the (1-8) peptide fragment of VLDLR (very low density lipoprotein receptor (show VLDLR ELISA Kits)), the second and third Lys (show LYZ ELISA Kits)/Arg clusters in fibrin make major contributions to this interaction while the contribution of the first cluster is moderate.
The novel missense mutation in the FGB gene causes afibrinogenemia most probably by affecting the secretion of the fibrinogen beta-chain.
fibrinogen aggregation is accompanied by the formation of beta-sheet conformation, and induction of non-native helical segments in the protein inhibits aggregation
fibrinogen is an independent predictor of the angiographic presence of coronary artery disease in hypertensive patients.
The molecular characterization of two novel afibrinogenemic mutations in the fibrinogen A alpha and fibrinogen B beta chain establishes the importance of the A alpha and B beta C-terminal region for normal fibrinogen assembly and secretion.
Data suggest that the interaction between Abeta and fibrinogen may be an important contributor to the vascular abnormalities found in Alzheimer's disease.
beta(3) integrin, thrombin (show F2 ELISA Kits), and Ca(2 (show CA2 ELISA Kits)+) play critical roles in platelet aggregation without fibrinogen or VWF (show VWF ELISA Kits)
Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
fibrinogen beta chain
, fibrinogen, beta chain
, B fibrinopeptide
, fibrinogen beta chain-like
, fibrinogen, B beta polypeptide
, B beta polypeptide
, fibrinogen, beta polypeptide
, liver regeneration-related protein LRRG036/LRRG043/LRRG189