You are viewing an incomplete version of our website. Please click to reload the website as full version.

Fibroblast Growth Factor 14 Proteins (FGF14)

The protein encoded by FGF14 is a member of the fibroblast growth factor (FGF) family. Additionally we are shipping FGF14 Antibodies (40) and FGF14 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FGF14 2259 Q92915
FGF14 14169 P70379
FGF14 63851 Q8R5L7
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top FGF14 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Dog Un-conjugated 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
$420.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,632.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FGF14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced FGF14 Proteins

  1. Human FGF14 Protein expressed in Escherichia coli (E. coli) - ABIN2005837 : Zhao, Lim, Tan: Genetic analysis of SCA 27 in ataxia and childhood onset postural tremor. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007 (PubMed)

More Proteins for Fibroblast Growth Factor 14 (FGF14) Interaction Partners

Human Fibroblast Growth Factor 14 (FGF14) interaction partners

  1. study reports on a two-generation French Canadian family affected with autosomal dominant episodic ataxia (show USP14 Proteins) caused by a frameshift mutation leading to a premature stop codon in FGF14

  2. identified the PI3K/Akt pathway, the cell-cycle regulator Wee1 kinase, and protein kinase C (PKC) as prospective regulatory nodes of neuronal excitability through modulation of the FGF14:Nav1.6 complex.

  3. family demonstrates phenotypic variability of FGF14 deletions (SCA 27), fever sensitivity of ataxia (show USP14 Proteins) and the added value of SNP-array analysis in making a diagnosis

  4. inhibition of GSK3 reduces the assembly of the FGF14.Nav channel complex, modifies FGF14-dependent regulation of Na(+) currents, and induces dissociation and subcellular redistribution of the native FGF14.Nav channel complex in hippocampal neurons.

  5. THe present study demonstrates that Spinocerebellar ataxia (show USP14 Proteins) type 27 (SCA27) caused by FGF14 mutation is rare in Chinese SCA patients.

  6. A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebral ataxia (show USP14 Proteins)

  7. A G->A variant was found in a single spinocerebellar ataxia (show USP14 Proteins) patient in the 3' untranslated region, 31 bp to the STOP codon; it did not affect the polyadenylation site. FGF14 mutations are not a major cause of SCA in Caucasians.

  8. Frameshift mutation and polymorphisms in the fibroblast growth factor 14 gene is associated with ataxias

  9. these findings implicate FGF14 as a unique modulator of Nav channel activity in the CNS.

  10. a distinct SCA (spinocerebellar ataxia (show USP14 Proteins))phenotype (SCA27) is associated with a F145S mutation in the fibroblast growth factor 14 (FGF14) gene on chromosome 13q34.

Mouse (Murine) Fibroblast Growth Factor 14 (FGF14) interaction partners

  1. TWEAK (show TNFSF12 Proteins)/Fn14 (show TNFRSF12A Proteins) pathway instrumental in the pathogenesis of spontaneous lupus nephritis

  2. FGF14 is localized in a decreasing proximal to distal gradient along the axon initial segment of Purkinje neurons.

  3. FGF14 regulates presynaptic Ca2 (show CA2 Proteins)+ channels and synaptic transmission in cultured rat neurons.

  4. inhibition of GSK3 reduces the assembly of the FGF14.Nav channel complex, modifies FGF14-dependent regulation of Na(+) currents, and induces dissociation and subcellular redistribution of the native FGF14.Nav channel complex in hippocampal neurons.

  5. Fgf14-deficient mice developed ataxia (show USP14 Proteins) and a paroxysmal hyperkinetic movement disorder. FGF14 may mediate neuronal signaling, axonal trafficking and synaptosomal function.

  6. FGF14 in regulating synaptic plasticity via presynaptic mechanisms by affecting the mobilization, trafficking, or docking of synaptic vesicles to presynaptic active zones.

  7. these results suggest a role for FGF14 in certain spatial learning functions and synaptic plasticity

  8. Sodium channels in Fhf1 (show FGF12 Proteins)-/-Fhf4-/- granule neurons inactivate at more negative membrane potential, inactivate more rapidly, and are slower to recover from the inactivated state.

  9. results suggest that FGF14 is required for normal Nav1.6 (show SCN8A Proteins) expression in Purkinje neurons, and that the loss of FGF14 impairs spontaneous and repetitive firing in Purkinje neurons by altering the expression of Nav1.6 (show SCN8A Proteins) channels

FGF14 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with FGF14

  • fibroblast growth factor 14 (FGF14)
  • fibroblast growth factor 14 (fgf14)
  • fibroblast growth factor 14 (LOC100229510)
  • fibroblast growth factor 14 (LOC100358876)
  • fibroblast growth factor 14 (Fgf14)
  • FGF-14 protein
  • FGF14 protein
  • FHF-4 protein
  • Fhf4 protein
  • mFHF-4(1B) protein
  • SCA27 protein

Protein level used designations for FGF14

fibroblast growth factor homologous factor 4 , fibroblast growth factor 14 , bA397O8.2 , FGF-14 , FGF homologus factor 4b

GENE ID SPECIES
395554 Gallus gallus
497642 Danio rerio
701077 Macaca mulatta
739338 Pan troglodytes
100217328 Xenopus (Silurana) tropicalis
100229510 Taeniopygia guttata
100358876 Oryctolagus cuniculus
2259 Homo sapiens
14169 Mus musculus
63851 Rattus norvegicus
485537 Canis lupus familiaris
615488 Bos taurus
Selected quality suppliers for FGF14 Proteins (FGF14)
Did you look for something else?