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The protein encoded by FRS3 is a substrate for the fibroblast growth factor receptor. Additionally we are shipping Fibroblast Growth Factor Receptor Substrate 3 Antibodies (45) and Fibroblast Growth Factor Receptor Substrate 3 Proteins (5) and many more products for this protein.
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signaling via Pax6 expression through Shp2-binding sites of XFrs3 is necessary for the eye development in Xenopus laevis
Mechanisms by which FRS2beta acts as a feedback inhibitor of EGFR (show EGFR ELISA Kits) family members and suggest a role for FRS2beta as a tumor suppressor.
an FRS2beta-CIN85 (show SH3KBP1 ELISA Kits)/CD2AP (show Cd2ap ELISA Kits)-Cbl (show CBL ELISA Kits) axis for downregulation of ErbB2 (show ERBB2 ELISA Kits) may regulate ErbB2 (show ERBB2 ELISA Kits) protein levels in physiological and pathological settings
FRS2 (show FRS2 ELISA Kits) PTB (show PTBP1 ELISA Kits) domain conformation regulates interactions with divergent neurotrophic receptors
FRS2beta can compensate for the loss of FRS2alpha (show FRS2 ELISA Kits) for activation of MAP kinase (show MAPK1 ELISA Kits) when expressed in fibroblasts
SNT-2 (show SNTB1 ELISA Kits) negatively regulates ERK2 (show MAPK1 ELISA Kits) signaling activated via EGF (show EGF ELISA Kits) stimulation through direct binding to ERK2 (show MAPK1 ELISA Kits)
Novel mechanism of negative control of EGFR (show EGFR ELISA Kits) tyrosine kinase (show TXK ELISA Kits) activity with SNT-2 (show SNTB1 ELISA Kits) by recruiting ERK2 (show MAPK1 ELISA Kits).
Analysis of a mutant Fgfr1 (show FGFR1 ELISA Kits) allele, unable to bind to the adaptor protein, Frs2 (show FRS2 ELISA Kits)/3, indicates that Sox2 (show SOX2 ELISA Kits) maintenance can be
data indicate that the fibroblast growth factor receptor substrate 2 (show FRS2 ELISA Kits) and fibroblast growth factor receptor substrate 3 adapters may have a role in thyroid carcinogenesis triggered by TRK (show NTRK1 ELISA Kits) oncogenes
Some essential functions of Fgfr1 (show FGFR1 ELISA Kits) are mediated by Frs (show SLC25A37 ELISA Kits)-independent signaling.
ULK2 (show ULK2 ELISA Kits), by interaction with FRS2 (show FRS2 ELISA Kits)/3 and inhibition of SynGAP (show SYNGAP1 ELISA Kits), functions to negatively regulate tyrosyl phosphorylation of signaling proteins downstream of FGFR1 (show FGFR1 ELISA Kits).
SNT family proteins may play significant roles in cellular transformation triggered by NPM (show NPM1 ELISA Kits)-ALK (show ALK ELISA Kits).
The results showed that the interaction of full-length FRS2beta with FGFR1 (show FGFR1 ELISA Kits) was not enhanced by activation of the receptor kinase.
Prominent expression of Frs2beta protein in neural cells and its association with intracellular vesicles is reported.
The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras.
fibroblast growth factor receptor substrate 3
, FGFR substrate 3
, FGFR-signaling adaptor SNT2
, suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor)
, suc1-associated neurotrophic factor target 2