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Filamin Binding LIM Protein 1 Proteins (FBLIM1)

FBLIM1 encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. Additionally we are shipping FBLIM1 Antibodies (50) and FBLIM1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBLIM1 54751 Q8WUP2
FBLIM1 74202 Q71FD7
Rat FBLIM1 FBLIM1 362650  
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Top FBLIM1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,039.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FBLIM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Filamin Binding LIM Protein 1 (FBLIM1) Interaction Partners

Human Filamin Binding LIM Protein 1 (FBLIM1) interaction partners

  1. the present study emphasizes for the first time to our knowledge the role of Migfilin in osteoarthritis(OA) and highlights the importance of cell-ECM (show MMRN1 Proteins) adhesion proteins in OA pathogenesis.

  2. Migfilin expression is reduced in breast cancer.

  3. alpha-parvin (show PARVA Proteins), beta-parvin (show PARVB Proteins) and migfilin were expressed in tumor cells in 53%, 2%, 28% and 53% of effusions and 57%, 20%, 83% and 25% of solid lesions, respectively.

  4. Migfilin positively modulates the expression and activity of epidermal growth factor receptor (show EGFR Proteins), and Migfilin-mediated migration and invasion depend on epidermal growth factor receptor (show EGFR Proteins)-induced PLC (show HSPG2 Proteins)-gamma and STAT3 (show STAT3 Proteins)-signaling pathways.

  5. Migfilin promoted beta-catenin degradation by reinforcing the association between beta-catenin and GSK-3beta.

  6. Migfilin can activate beta1, beta2 and beta3 integrins and promote integrin mediated responses while migfilin depletion impairs the spreading and migration of endothelial cells

  7. The association between filamin B (show FLNB Proteins) and FBLP-1 may play a hitherto unknown role in cytoskeletal function, cell adhesion, and cell motility.

  8. Migfilin has a role in interacting with vasodilator-stimulated phosphoprotein (VASP (show VASP Proteins)) and regulates VASP (show VASP Proteins) localization to cell-matrix adhesions and migration

  9. Results suggest a role for cytoplasmic migfilin in the progression of leiomyosarcomas (LMS) and identify cytoplasmic migfilin as a potentially important biological marker for human LMS progression.

  10. Loss-of-function mutations in KIND1 (show FERMT1 Proteins) result in marked variability in kindlin-1 (show FERMT1 Proteins) immunolabeling in Kindler syndrome skin, which is mirrored by similar changes in kindlin-2 (show FERMT2 Proteins) and migfilin immunoreactivity.

Mouse (Murine) Filamin Binding LIM Protein 1 (FBLIM1) interaction partners

  1. Suggest migfilin regulates cardiac hypertrophy in transverse aortic constriction.

  2. C-terminal LIM (show PDLIM5 Proteins) domains of migfilin dictate its focal adhesion localization, and these domains mediate an interaction with kindlin in vitro and in cells, demonstrating that kindlin is important for normal migfilin dynamics.

  3. results identify FBLP-1 as a key regulator of bone homeostasis and suggest that FBLP-1 functions in this process through modulating both the intrinsic properties of OB/BMSCs (i.e., BMSC-extracellular matrix adhesion and migration

  4. This study demonistrated that a molecular mechanism whereby FlnA (show FLNA Proteins) loss impaired G2 to M phase entry, leading to cell cycle prolongation, compromised neural progenitor proliferation, and reduced brain size.

  5. The findings indicate that the roles of migfilin are functionally redundant during mouse development and tissue homeostasis.

  6. results suggest that a novel LIM protein (show PDLIM1 Proteins) Cal (show S100A11 Proteins) induces cardiomyocyte differentiation through its dynamic intracellular shuttling and association with CSX/NKX2-5 (show NKX2-5 Proteins)

  7. analysis of the migfilin-filamin (show FLNA Proteins) interaction and competition with integrin beta 7 (show ITGB7 Proteins) tails

FBLIM1 Protein Profile

Protein Summary

This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with FBLIM1

  • filamin binding LIM protein 1 (FBLIM1)
  • filamin binding LIM protein 1 (fblim1)
  • filamin binding LIM protein 1 (Fblim1)
  • 2410043F08Rik protein
  • Cal protein
  • FBLIM1 protein
  • FBLP-1 protein
  • Fblp1 protein
  • Gt10 protein
  • migfilin protein
  • migfilin(s) protein

Protein level used designations for FBLIM1

filamin binding LIM protein 1 , filamin-binding LIM protein-1 , FBLP-1 , filamin-binding LIM protein 1 , CSX-associated LIM , MIG2-interacting protein , migfilin , mitogen-inducible 2 interacting protein , mitogen-inducible 2-interacting protein

GENE ID SPECIES
419458 Gallus gallus
608618 Canis lupus familiaris
740207 Pan troglodytes
100137707 Xenopus laevis
100174248 Pongo abelii
54751 Homo sapiens
74202 Mus musculus
767833 Bos taurus
362650 Rattus norvegicus
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