Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Additionally we are shipping FMO5 Proteins (5) and many more products for this protein.
Showing 10 out of 62 products:
Human Polyclonal FMO5 Primary Antibody for WB - ABIN1881348
Furnes, Feng, Sommer, Schlenk: Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans. in Drug metabolism and disposition: the biological fate of chemicals 2003
Show all 2 references for 1881348
Cow (Bovine) Polyclonal FMO5 Primary Antibody for IHC, WB - ABIN2782128
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
Nabumetone and pentoxifylline, two widely used pharmaceuticals, were thereby demonstrated to be efficiently oxidized in vitro by FMO5 to the corresponding acetate esters with high selectivity.
absence of the typical characteristic sequence motifs sets human FMO5 apart from all characterized Baeyer-Villiger mono-oxygenases so far. These findings open new perspectives in human oxidative metabolism
fmo5 displayed a significant, dominant liver-specific mRNA profile.
The phenotype of a knockout mouse identifies FMO5 as a regulator of metabolic aging.
The functional activity of Fmo5 was determined.
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
flavin containing monooxygenase 5
, Dimethylaniline monooxygenase 5
, dimethylaniline monooxygenase [N-oxide-forming] 5-like
, FMO 5
, dimethylaniline monooxygenase [N-oxide-forming] 5
, dimethylaniline oxidase 5
, hepatic flavin-containing monooxygenase 5
, FMO 1C1
, FMO form 3
, dimethylanaline monooxygenase