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FSTL1 encodes a protein with similarity to follistatin, an activin-binding protein. Additionally we are shipping FSTL1 Kits (44) and FSTL1 Proteins (27) and many more products for this protein.
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Human Polyclonal FSTL1 Primary Antibody for ELISA, WB - ABIN184815
Tanaka, Ozaki, Osakada, Mori, Okubo, Nakao: Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases. in International immunology 1998
Show all 2 references for ABIN184815
Human Polyclonal FSTL1 Primary Antibody for EIA, FACS - ABIN952355
Kai, Iwase, Imai, Nakahira, Soma, Ohtsuka, Yagi, Kobayashi, Koga, Takiguchi, Yuasa: Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis. in Brain research 2006
Show all 2 references for ABIN952355
Human Polyclonal FSTL1 Primary Antibody for ELISA - ABIN1997777
Rosenberg, Georges, Asawachaicharn, Analau, Tapscott: MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206. in The Journal of cell biology 2006
this study shows that 1) the expression of follistatin-like protein 1 is upregulated in rheumatoid arthritis patients; 2) miR-27a inhibits cell migration of rheumatoid arthritis synoviocytes by targeting follistatin-like protein 1 and restraining the TLR4/NFkappaB pathway
FSTL1 plays a critical role in immune regulation, enhancing the antigen presentation ability of dendritic cells by up-regulating NF-kappab (show NFKB1 Antibodies) expression and down-regulating JNK (show MAPK8 Antibodies) expression.
the knockdown of FSTL1 induces apoptosis through a mitotic arrest and caspase (show CASP3 Antibodies)-dependent cell death. FSTL1 plays the important roles in cellular proliferation and apoptosis in lung cancer cells, and thus can be a new target for lung cancer treatment.
Children with chronic heart failure group had a significantly higher serum level of FSTL1 than the control group.
provide mechanistic insight into the regulation of erythropoiesis by FSTL1 signaling and lay a foundation for exploring FSTL1 signaling as a therapeutic target for anemia
FSTL1 is elevated in patients with osteoarthritis and involved in the progression of synovial inflammation.
administration of Fstl1 induced airway remodeling and increased OSM (show OSM Antibodies), whereas administration of an anti-OSM (show OSM Antibodies) Ab blocked the effect of Fstl1 on inducing airway remodeling, eosinophilic airway inflammation
data suggest that the loss of epicardial FSTL1 is a maladaptive response to injury, and that its restoration would be an effective way to reverse myocardial death and remodelling following myocardial infarction in humans
Fstl1 is induced in response to lung injury and promotes the accumulation of myofibroblasts and subsequent fibrosis. These data suggest that Fstl1 may serve as a novel therapeutic target for treatment of progressive lung fibrosis.
FSTL1 is elevated in various inflammatory conditions and decreased during the course of treatment. FSTL1 may therefore be a valuable biomarker for such diseases.
a new role for FSTL1 in the development of radial glial scaffolds and the neuronal migration of upper-layer projection neurons, is reported.
epicardial cells contain a potent cardiogenic activity identified as follistatin-like 1 (Fstl1)
FSTL1 is a potent regulator of chondrocyte proliferation, differentiation and expression of extracellular matrix molecules.
muscle-derived Fstl1 attenuates neointimal formation in response to arterial injury by suppressing smooth muscle cell proliferation through an AMPK (show PRKAA1 Antibodies)-dependent mechanism
functions in cardiorenal communication; lack of Fstl1 production by myocytes promotes glomerular and tubulointerstitial damage in the kidney
This study is the first to describe a role for FSTL-1 in the development of Lyme arthritis and anti-Borrelia response.
FSTL1 is a potential mediator of inflammation and insulin (show INS Antibodies) resistance in obesity.
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.
, Follistatin-related protein 1
, follistatin-like protein 1
, follistatin-related protein 1
, TGF-beta-inducible protein TSC-36