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FOXA1 encodes a member of the forkhead class of DNA-binding proteins. Additionally we are shipping FOXA1 Proteins (8) and many more products for this protein.
Showing 10 out of 196 products:
Cow (Bovine) Polyclonal FOXA1 Primary Antibody for ChIP, EIA - ABIN782926
Eeckhoute, Lupien, Meyer, Verzi, Shivdasani, Liu, Brown: Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. in Genome research 2009
Show all 8 references for ABIN782926
Human Monoclonal FOXA1 Primary Antibody for IF, WB - ABIN394359
Liu, Niu, Wang, Yu, Zhang, Liu: [Diagnostic and prognostic significance of FOXA1 expression in molecular subtypes of breast invasive ductal carcinomas]. in Zhonghua yi xue za zhi 2010
Show all 5 references for ABIN394359
Human Polyclonal FOXA1 Primary Antibody for EIA, WB - ABIN952360
Hu, Gardner-Stephen, Severi, Gregory, Treloar, Giles, English, Hopper, Tilley, Mackenzie: A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide. in Molecular pharmacology 2010
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Human Polyclonal FOXA1 Primary Antibody for WB - ABIN658712
Zhang, Liang, Li, Xuan, Wang, Wang, Shi, Zhang, Shang: CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen. in The Journal of biological chemistry 2010
Show all 3 references for ABIN658712
Chicken Polyclonal FOXA1 Primary Antibody for WB - ABIN2780597
Lupien, Eeckhoute, Meyer, Wang, Zhang, Li, Carroll, Liu, Brown: FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. in Cell 2008
Show all 2 references for ABIN2780597
Human Monoclonal FOXA1 Primary Antibody for ChIPSeq, ChIP - ABIN2668682
Nucera, Eeckhoute, Finn, Carroll, Ligon, Priolo, Fadda, Toner, Sheils, Attard, Pontecorvi, Nose, Loda, Brown: FOXA1 is a potential oncogene in anaplastic thyroid carcinoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Show all 2 references for ABIN2668682
Human Polyclonal FOXA1 Primary Antibody for IHC, ELISA - ABIN185021
Lin, Miller, Contreras, Prescott, Dagenais, Wu, Yee, Orringer, Misek, Hanash, Glover, Beer: The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas. in Cancer research 2002
Cow (Bovine) Polyclonal FOXA1 Primary Antibody for WB - ABIN2779762
Williamson, Wolf, OKelly, Bose, Tanosaki, Koeffler: BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1). in Oncogene 2006
There is significantly increased esophageal squamous cell carcinoma risk associated with the FOXA1 rs7144658 T > C polymorphism among male patients.
Meta-analysis results clearly point to an important role of FOXA1 and FOXA2 (show FOXA2 Antibodies) gene regulatory networks in the etiology of Alzheimer's disease
show that ER and GR both have the ability to alter the genomic distribution of the FoxA1 pioneer factor. Single-molecule tracking experiments reveal a highly dynamic interaction of FoxA1 with chromatin in vivo; FoxA1 factor is not associated with footprints at its binding sites throughout the genome; findings support a model wherein interactions between transcription factors and pioneer factors are highly dynamic.
findings suggest a key role for GalNAc-T4 (show GALNT4 Antibodies) in the estrogen pathway through FOXA1 glycosylation
The ratio of FoxA1 to FoxA2 (show FOXA2 Antibodies) in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor (show ASH1L Antibodies) LSH (show HELLS Antibodies)
Loss of Interdependent Binding by the FoxO1 (show FOXO1 Antibodies) and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Antibodies)-sensitive Genes.
FoxA1, FoxA2 (show FOXA2 Antibodies), and LIPG (show LIPG Antibodies) control the uptake of extracellular lipids for breast cancer growth.
The expression of FOXA1 appears to be involved in the proliferation of immature breast cancer cells rather than the induction of stemness-related genes and self-renewal potency of cancer stem cells.
Data suggests that androgen receptor (show AR Antibodies) variants (AR-Vs) are dependent on forkhead box A1 protein (FOXA1) for sustaining a pro-proliferative gene signature.
FOXA1 expression is associated with a less aggressive phenotype and a better prognosis in patients with hormone receptor (show NR4A1 Antibodies)-positive/HER2 (show ERBB2 Antibodies)-negative breast cancer.
this model system will facilitate further in vivo functional studies of Foxa1 or other factors in mammary gland development and tumor formation and progression
genome-wide binding sites of the forkhead/winged helix transcription factor (show FOXP2 Antibodies) Foxa1, which functions redundantly with Foxa2 (show FOXA2 Antibodies) to regulate the differentiation of midbrain dopamine neurons, were characterized.
Disruption of Shp (show LAMC1 Antibodies) in mice alters timing of expression of genes that regulate homocysteine metabolism and the liver responses to ethanol and homocysteine. SHP (show LAMC1 Antibodies) inhibits the transcriptional activation of Bhmt (show BHMT Antibodies) and cystathionine gamma-lyase (show CTH Antibodies) by FOXA1.
ChIP-exonuclease of the ER pioneer factor FoxA1 identifies protected DNA with a predictable 8 bp overhang from the Forkhead motif, which authors term mesas; showed that mesas occur in multiple cellular contexts and exist as single or overlapping motifs.
TIP30 (show HTATIP2 Antibodies) is a key regulator for maintaining ER(+) and ER(-)luminal pools in the mammary luminal lineage via FoxA1.
Mechanistically, JARID1B (show KDM5B Antibodies) was required for GATA3 (show GATA3 Antibodies) recruitment to the Foxa1 promoter to activate Foxa1 expression.
Foxa1 recruited Grg3 to the Nanog (show NANOG Antibodies) promoter -2kb upstream region and switched the promoter to an inactive chromatin status represented by typical modifications in histone H3 (show HIST3H3 Antibodies).
Results indicate Foxa1 expression is required for the maintenance of prostatic cellular differentiation.
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
forkhead box A1
, forkhead box protein A4
, HNF-3 alpha
, HNF3 alpha
, forkhead box protein A1
, forkhead transcription factor FoxA1
, forkhead homolog
, hepatocyte nuclear factor 3-alpha-like
, fork head domain protein 7
, hepatocyte nuclear factor 3-alpha
, HNF3alpha homolog B
, fork head domain-related protein 7'
, forkhead box protein A1-B
, forkhead protein 2
, hepatocyte nuclear factor 3-alpha homolog B
, transcription factor 3A
, hepatocyte nuclear factor 3 alpha
, fork head domain
, hepatocyte nuclear factor 3 alpha (winged helix transcription factor)
, hepatocyte nuclear factor 3, alpha