FOXA1 antibody (C-Term)

Catalog No. ABIN2779762

The Rabbit Polyclonal anti-FOXA1 antibody is suitable to detect FOXA1 in samples from Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig and Saccharomyces cerevisiae. It has been validated for WB and IHC.

Quick Overview for FOXA1 antibody (C-Term) (ABIN2779762)

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FOXA1 Antibody

Binding Specificity: C-Term

Purpose: FOXA1 Antibody - C-terminal region

Sequence: SFNHPFSINN LMSSSEQQHK LDFKAYEQAL QYSPYGSTLP ASLPLGSASV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FOXA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100819

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXA1

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Alternative Name: FOXA1

Background:

Background Information: FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

Gene Name: Forkhead box A1

Alternative Symbols: HNF3A, TCF3A

Molecular Weight: 49kDa

Gene ID: 3169

NCBI Accession: NP_004487

UniProt: Q0JTB6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis