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Possible transcriptional factor (By similarity).. Additionally we are shipping FOXI3 Proteins (2) and many more products for this protein.
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Foxi3 is necessary to prime pre-placodal ectoderm for the correct interpretation of inductive signals for the otic and epibranchial placodes.
Foxi3 maintains dental epithelial cells in an undifferentiated state and thereby regulates multiple stages of tooth morphogenesis.
Data indicate that Foxi3 mutants succumb to apoptosis from embryonic day 9.75 onwards, and this cell death correlates with a delay in expression of Fgf8 in branchial arch ectoderm.
Eda (show EDA Antibodies) and activin A (show INHBA Antibodies) are upstream regulators of Foxi3 in skin appendage placodes
Foxi3 expressed in a broad region of the pan (show SUPT6H Antibodies)-placodal ectoderm adjacent to the neural plate from E6.75 to first somite stage; expression restricted to ectoderm & endoderm of branchial pouches at E10.5
Possible transcriptional factor (By similarity).
forkhead box I3
, forkhead box protein I3