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The protein encoded by FOXK2 contains a fork head DNA binding domain. Additionally we are shipping Forkhead Box K2 Proteins (3) and many more products for this protein.
Showing 10 out of 69 products:
Human Polyclonal FOXK2 Primary Antibody for ELISA, WB - ABIN249974
Fujii, Nakamura: FOXK2 transcription factor is a novel G/T-mismatch DNA binding protein. in Journal of biochemistry 2010
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Cow (Bovine) Polyclonal FOXK2 Primary Antibody for IHC, WB - ABIN2776014
Liu, Chen, Li, Hsieh, Chen, Chen, Jeng, Chuang: Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a). in Proteins 2002
Show all 2 Pubmed References
SOX9 (show SOX9 Antibodies) transcriptionally activated FOXK2 was involved in the pathogenesis of colorectal cancer.FOXK2 is highly expressed in colorectal cancer tissues.
Results show that Foxk2 expression was downregulated in lung adenocarcinoma tissues and non-small cell lung cancer cell (NSCLC) lines. Its overexpression suppresses epithelial-mesenchymal transition in NSCLC cells and inhibits cell migration and invasion. Also, the expression of Foxk2 seems to be regulated by miR (show MLXIP Antibodies)-1271.
FOXO3 (show FOXO3 Antibodies)-dependent gene regulation is generally mediated not through uniquely bound regions but through regions occupied by both FOXK2 and FOXO3 (show FOXO3 Antibodies) where both factors play a regulatory role.
FOXK2 might act as a negative regulator of ERalpha (show ESR1 Antibodies), and its association with both ERalpha (show ESR1 Antibodies) and BRCA1/BARD1 (show BARD1 Antibodies) could lead to the down-regulation of ERalpha (show ESR1 Antibodies) transcriptional activity, effectively regulating the function of ERalpha (show ESR1 Antibodies).
FOXK1 and FOXK2 positively regulate Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling by translocating dishevelled (show DVL2 Antibodies) proteins into the nucleus.
BAP1 (show RNF2 Antibodies) deficiency causes increased expression of FoxK2 target genes in a Ring1B (show RNF2 Antibodies)-Bmi1 (show BMI1 Antibodies)-dependent manner
FOXK2 can promote transcriptional activation and is required for the efficient recruitment of AP-1 (show FOSB Antibodies) components to chromatin.
Data show that FOXK2 is subject to control by cell cycle-regulated hyperphosphorylation occurring in CDK (show CDK4 Antibodies)).cyclin (show PCNA Antibodies)-dependent manner with CDK1 (show CDK1 Antibodies).cyclin B as the major kinase complex.
FOXK2 is a G/T-mismatch DNA-binding protein (show UBE2V1 Antibodies) and a deaminated DNA-binding protein (show UBE2V1 Antibodies)
FoxK2 is required for proliferation and survival.
Foxk1 (show Foxk1 Antibodies) and Foxk2 are identified as transcriptional repressors of autophagy in muscle cells and fibroblasts.
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements.
, forkhead box protein K2
, forkhead box K2
, cellular transcription factor ILF-1
, interleukin enhancer binding factor 1
, interleukin enhancer-binding factor 1