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GAGE1 belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Additionally we are shipping G Antigen 1 Antibodies (7) and many more products for this protein.
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MAGE (show MAGEB10 Proteins)-A1 and NY-ESO-1 (show CTAG1B Proteins) are associated with highly proliferating germ cells, whereas GAGE proteins have a more general function in germ cells unrelated to any specific developmental stage
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants.
, cancer/testis antigen 4.1
, cancer/testis antigen family 4, member 1