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Orphan receptor. Additionally we are shipping GPR78 Kits (14) and GPR78 Proteins (3) and many more products for this protein.
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Knockdown of GPR78 in lung cancer cells suppressed cell migration and GPR78 modulated the formation of actin stress fibers in A549 cells, in a RhoA- and Rac1-dependent manner.
Two haplotypes remained significant in both the female bipolar affective disorder individuals and in the full sample of affected female individuals. Results provide preliminary evidence for involvement of GPR78 in susceptibility to BPAD and SCZ.
Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
G-protein coupled receptor 78
, G protein-coupled receptor 78