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anti-G Protein-Coupled Receptor Kinase 1 (GRK1) Antibodies

Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity). Additionally we are shipping G Protein-Coupled Receptor Kinase 1 Kits (9) and G Protein-Coupled Receptor Kinase 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRK1 6011 Q15835
GRK1 24013  
GRK1 81760 Q63651
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Top anti-G Protein-Coupled Receptor Kinase 1 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with TNF 20ng/ml 5', using GRK1 (Phospho-Ser21) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using GRK1 (Phospho-Ser21) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, using GRK1 (Ab-21) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GRK1 (Ab-21) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB (LEFT)Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (RIGHT)Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GRK1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. The anti-GRK1 Pab is used in Western blot to detect GRK1 in HeLa cell lysate (Lane 1) and mouse spleen tissue lysate (Lane 2). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GRK1 AntibodyTitration: 1.0 µg/mL  Positive Control: Jurkat Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-GRK1 Pab (ABIN390984) is used in Western blot to detect GRK1 in HeLa cell lysate (Lane 1) and mouse spleen tissue lysate (Lane 2). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

GRK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-G Protein-Coupled Receptor Kinase 1 Antibodies

  1. Human Polyclonal GRK1 Primary Antibody for EIA, IHC (p) - ABIN359042 : Zhao, Huang, Khani, Palczewski: Molecular forms of human rhodopsin kinase (GRK1). in The Journal of biological chemistry 1998 (PubMed)
    Show all 5 references for ABIN359042

  2. Human Polyclonal GRK1 Primary Antibody for IHC, ELISA - ABIN1531605 : Khani, Abitbol, Yamamoto, Maravic-Magovcevic, Dryja: Characterization and chromosomal localization of the gene for human rhodopsin kinase. in Genomics 1996 (PubMed)

More Antibodies against G Protein-Coupled Receptor Kinase 1 Interaction Partners

Human G Protein-Coupled Receptor Kinase 1 (GRK1) interaction partners

  1. In the Ca(2 (show CA2 Antibodies)+)/NCS-1 (show NCS1 Antibodies).D2R (show DRD2 Antibodies) peptide complex, the C-terminal region adopts a 310 helix-turn-310 helix, whereas in the GRK1 peptide complex it forms an a-helix

  2. Rho-kinase (show ROCK1 Antibodies) activity exhibits distinct circadian variation associated with alterations in coronary vasomotor responses and autonomic activity in VSA patients.

  3. The selective thinning of the inner retinal layers in patients with GRM6 (show GRM6 Antibodies) mutations suggests either reduced bipolar or ganglion cell numbers or altered synaptic structure in the inner retina.

  4. Defects in GRK1 or GRK7 (show GRK7 Antibodies) cause patients to suffer from an inability to properly deactivate rhodopsin (show RHO Antibodies) leading to problems with recovery and dark adaptation.

  5. There are two genes that cause Oguchi disease: the G protein-coupled receptor kinase 1 gene and the S antigen (show SAG Antibodies) gene. There is evidence that Oguchi disease and retinitis pigmentosa (RP) can coexist in the same family or even in the same individual

  6. Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated.

  7. The disease in the Pakistani family localizes to 13q34 and is caused by a novel deletion including Exon 3 of the GRK1 gene.

  8. G protein-coupled receptor kinase site serine cluster has a role in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation

  9. RhoK activation in brain microvascular endothelial cells could be a cause of blood-brain barrier impairment during HIV-1 encephalitis.

  10. A novel homozygous GRK1 mutation (p.P391H) was found in 2 Japanese siblings with Oguchi disease.

Cow (Bovine) G Protein-Coupled Receptor Kinase 1 (GRK1) interaction partners

  1. The C-terminal segment in GCAP2 (show GUCA1B Antibodies) confers target selectivity, facilitates membrane binding and provides sensitivity of the membrane localization of the protein to phosphorylation by rhodopsin kinase.

  2. The methylation status of GRK1 is affected by nucleotide binding and by the levels of free Ca2 (show CA2 Antibodies) + via recoverin (show RCVRN Antibodies).

  3. crystalline dimer interface was disrupted with a L166K mutation and the structure of GRK1-L166K was determined in complex with Mg(2 (show MCOLN1 Antibodies)+) . ATP to 2.5 A resolution

  4. A novel rhodopsin-kinase-binding site within the C-terminal region of recoverin (show RCVRN Antibodies).

  5. similar to transducin (show GNAT1 Antibodies) activation, rhodopsin (show RHO Antibodies) phosphorylation by GRK1 and high affinity arrestin-1 (show SAG Antibodies) binding only requires a rhodopsin (show RHO Antibodies) monomer

  6. Recoverin (show RCVRN Antibodies) and rhodopsin kinase have roles in a Ca2 (show CA2 Antibodies)+-dependent feedback loop in membrane rafts from rod outer segments

  7. an interaction surface for the recoverin (show RCVRN Antibodies) target rhodopsin kinase is constituted upon Ca2 (show CA2 Antibodies)+ binding to the non-acylated mutant

  8. Recoverin (show RCVRN Antibodies) binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase

  9. Ca(2 (show CA2 Antibodies)+)-bound recoverin (show RCVRN Antibodies) is bound between rhodopsin (show RHO Antibodies) and RK in a ternary complex on rod outer segment disk membranes, thereby blocking RK interaction with rhodopsin (show RHO Antibodies) at high Ca(2 (show CA2 Antibodies)+)

  10. key elements of rhodopsin kinase in different ligand states are involved in G protein-coupled receptor (show GPBAR1 Antibodies) kinase activation

Mouse (Murine) G Protein-Coupled Receptor Kinase 1 (GRK1) interaction partners

  1. The retinal phenotype of Grk1-/- mice is compromised by a Crb1 (show CRB1 Antibodies) rd8 mutation.

  2. Rods and cones share the same isoforms of recoverin (show RCVRN Antibodies) and GRK1, and photoactivation also triggers a calcium decline in cones

  3. Knockout of Unc119 (show UNC119 Antibodies) partially reversed the transport defect of GRK1 in cone photoreceptors caused by deletion of Pde6d (show PDE6D Antibodies).

  4. rhodopsin kinase may modulate the decay of light-activated PDE (show TWIST1 Antibodies)*, which may be responsible for the quickening of response recovery in background light.

  5. Altering the expression of GRK1 from 0.3- to 3-fold that in wild-type rods had little effect on the single photon response amplitude.

  6. phototransduction does not play a direct role in the light-dependent dephosphorylation of GRK1.

  7. PLCdelta3 negatively regulates RhoA (show RHOA Antibodies) expression, inhibits RhoA (show RHOA Antibodies)/Rho kinase (show ROCK2 Antibodies) signaling, and thereby promotes neurite extension.

  8. The results of this study demonstrated a light-independent mechanism for retinal degeneration in the absence of GRK1, suggesting a second, not previously recognized role for that kinase.

  9. Nrl (show NRL Antibodies) and Grk1 have roles in photoresponse recovery and age-related degeneration

  10. transport of prenylated proteins, particularly GRK1 and cone phosphodiesterase, to rod and cone outer segments

G Protein-Coupled Receptor Kinase 1 (GRK1) Antigen Profile

Protein Summary

Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity).

Gene names and symbols associated with GRK1

  • G protein-coupled receptor kinase 1 (Gprk1) antibody
  • G protein-coupled receptor kinase 1 a (grk1a) antibody
  • G protein-coupled receptor kinase 1 (GRK1) antibody
  • G protein-coupled receptor kinase 1 (Grk1) antibody
  • CG40129 antibody
  • CT4320 antibody
  • Dmel\\CG40129 antibody
  • Gprk-1 antibody
  • Gprk1 antibody
  • grk1 antibody
  • Rhok antibody
  • Rk antibody
  • Rok antibody

Protein level used designations for GRK1

CG40129-PA , CG40129-PB , Gprk1-PA , Gprk1-PB , rhodopsin kinase , G-protein-coupled receptor kinase 1a , G-protein coupled receptor kinase 1 , RK , G-protein receptor kinase 1 , G protein-coupled receptpr kinase 1

GENE ID SPECIES
3355013 Drosophila melanogaster
564152 Danio rerio
395431 Gallus gallus
6011 Homo sapiens
281457 Bos taurus
24013 Mus musculus
81760 Rattus norvegicus
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