anti-G Protein-Coupled Receptor 124 (GPR124) Antibodies

Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Additionally we are shipping GPR124 Kits (1) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR124 100363275  
GPR124 25960 Q96PE1
GPR124 78560 Q91ZV8
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Top anti-GPR124 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Anti GPR124 Polyclonal Antibody, Unconjugated (ABIN763151) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of HeLa cells, using GPR124 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Allophycocyanin FACS Detection of TEM5/GPR124 in HEK293 Human Cell Line Transfected with Human TEM5/GPR124 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human TEM5/GPR124 and eGFP was stained with either (A) Mouse Anti-Human TEM5/GPR124 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$199.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human lung, adenocarcinoma. Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human colon carcinoma, neoplastic cells. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Bat Rabbit Un-conjugated IHC (p) Anti-GPR124 antibody  ABIN1048704 IHC staining of human colon carcinoma, neoplastic cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 7 to 9 Days
$478.50
Details
Human Mouse Un-conjugated FACS Detection of TEM5/GPR124 in HEK293 Human Cell Line Transfected with Human TEM5/GPR124 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human TEM5/GPR124 and eGFP was stained with either (A) Mouse Anti-Human TEM5/GPR124 Monoclonal Antibody. Detection of TEM5/GPR124 in HEK293 Human Cell Line Transfected with Human TEM5/GPR124 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human TEM5/GPR124 and eGFP was stained with either (A) Mouse Anti-Human TEM5/GPR124 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$288.75
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$466.62
Details

GPR124 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GPR124 Antibodies

  1. Human Polyclonal GPR124 Primary Antibody for IHC, ELISA - ABIN1003260 : Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: Cell surface tumor endothelial markers are conserved in mice and humans. in Cancer research 2001 (PubMed)
    Show all 4 references for 1003260

More Antibodies against GPR124 Interaction Partners

Zebrafish G Protein-Coupled Receptor 124 (GPR124) interaction partners

  1. The GPI (show ITGA2 Antibodies)-anchored MMP inhibitor Reck (show RECK Antibodies) and the adhesion GPCR (show GPRC6A Antibodies) Gpr124 are integral components of the Wnt7a (show WNT7A Antibodies)/Wnt7b (show WNT7B Antibodies)-specific signaling complex required for brain angiogenesis and dorsal root ganglia neurogenesis.

Human G Protein-Coupled Receptor 124 (GPR124) interaction partners

  1. Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1 (show ELMO1 Antibodies)-Dock180 (show DOCK1 Antibodies) and intersectin 1 (show ITSN1 Antibodies)/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 (show ELMO1 Antibodies) = ELMO domain-containing protein 1 (show ELMOD1 Antibodies); Dock180 (show DOCK1 Antibodies) = dedicator of cytokinesis protein 1 (show DOCK1 Antibodies) 180 kDa)

  2. Observed an inverse correlation between the expression of miR (show MLXIP Antibodies)-138-5p and GPR124 in lung adenocarcinoma specimens. Knockdown of GPR124 mimicked the effects of miR (show MLXIP Antibodies)-138-5p on the sensitivity to gefitinib.

  3. Thrombin (show F2 Antibodies)-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein (show CD28 Antibodies) disulfide-isomerase (show P4HB Antibodies).

  4. TEM5 expression during capillary morphogenesis is induced by the small GTPase (show RACGAP1 Antibodies) Rac (show AKT1 Antibodies) and mediates contact inhibition of proliferation in endothelial cells.

  5. Proteolytically processed soluble tumor endothelial marker TEM5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v (show ITGAV Antibodies))beta3 to glycosaminoglycans

Mouse (Murine) G Protein-Coupled Receptor 124 (GPR124) interaction partners

  1. experiments indicate that Reck (show RECK Antibodies) and Gpr124 are part of the cell surface protein (show CD28 Antibodies) complex that transduces Wnt7a (show WNT7A Antibodies)- and Wnt7b (show WNT7B Antibodies)-specific signals in mammalian CNS Epithelial Cells to promote angiogenesis and regulate the BBB (show ALMS1 Antibodies).

  2. Gpr124 is an endothelial GPCR (show GPBAR1 Antibodies) specifically required for endothelial Wnt (show WNT2 Antibodies) signaling and BBB (show ALMS1 Antibodies) integrity under pathological conditions in adult mice.

  3. Vital role for GPR124 is potentiation of WNT7 (show WNT7B Antibodies)-induced canonical beta-catenin (show CTNNB1 Antibodies) signaling with important implications for understanding and manipulating CNS-specific angiogenesis.

  4. Gpr124 functions as coactivator of Wnt7a (show WNT7A Antibodies)- and Wnt7b (show WNT7B Antibodies)-stimulated canonical Wnt (show WNT2 Antibodies) signaling via Frizzled receptor and Lrp (show LRP1 Antibodies) coreceptor and that Gpr124-stimulated signaling functions in concert with Norrin (show NDP Antibodies)/Frizzled4 (show FZD4 Antibodies) signaling to control CNS vascular development

  5. GPR124, an orphan G protein-coupled receptor (show GPRC5C Antibodies), is required for CNS-specific vascularization and establishment of the blood-brain barrier.

  6. TGF-beta (show TGFB1 Antibodies) stimulates Gpr124 expression which is required for angiogenic sprouting into neural tissues.

  7. study shows that complete null or endothelial-specific GPR124 deletion resulted in embryonic lethality from CNS-specific angiogenesis arrest in forebrain and neural tube; results demonstrate CNS-specific angiogenesis regulation by an endothelial receptor

GPR124 Antigen Profile

Protein Summary

Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.

Gene names and symbols associated with GPR124

  • G protein-coupled receptor 124 (gpr124) antibody
  • G protein-coupled receptor 124 (GPR124) antibody
  • G protein-coupled receptor 124 (LOC100363275) antibody
  • G protein-coupled receptor 124 (Gpr124) antibody
  • G-protein coupled receptor 124-like (LOC616111) antibody
  • 8430414O08Rik antibody
  • 9530074E10Rik antibody
  • GPR124 antibody
  • MGC69043 antibody
  • mKIAA1531 antibody
  • si:dkey-208c22.2 antibody
  • Tem5 antibody

Protein level used designations for GPR124

G protein-coupled receptor 124 , probable G-protein coupled receptor 124-like , G-protein coupled receptor 124 , tumor endothelial marker 5

GENE ID SPECIES
399052 Xenopus laevis
426771 Gallus gallus
472739 Pan troglodytes
560700 Danio rerio
698629 Macaca mulatta
100059646 Equus caballus
100363275 Rattus norvegicus
100472498 Ailuropoda melanoleuca
25960 Homo sapiens
78560 Mus musculus
482853 Canis lupus familiaris
100524344 Sus scrofa
306543 Rattus norvegicus
616111 Bos taurus
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