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GPR37 is a member of the G protein-coupled receptor family. Additionally we are shipping GPR37 Proteins (7) and GPR37 Kits (2) and many more products for this protein.
Showing 10 out of 70 products:
Human Polyclonal GPR37 Primary Antibody for EIA, IHC (p) - ABIN359006
Imai, Soda, Hatakeyama, Akagi, Hashikawa, Nakayama, Takahashi: CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. in Molecular cell 2002
Show all 4 references for ABIN359006
Human Polyclonal GPR37 Primary Antibody for EIA, IHC (p) - ABIN359005
Yang, Nishimura, Imai, Takahashi, Lu: Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. in Neuron 2003
Show all 4 references for ABIN359005
Human Polyclonal GPR37 Primary Antibody for ELISA, WB - ABIN1452210
Marazziti, Golini, Gallo, Lombardi, Matteoni, Tocchini-Valentini: Cloning of GPR37, a gene located on chromosome 7 encoding a putative G-protein-coupled peptide receptor, from a human frontal brain EST library. in Genomics 1997
Data suggest that GPR37 regulates central nervous system myelination by controlling the transition from early-differentiated to mature oligodendrocytes.
Knocking-out GPR37 triggers anxiolytic-like effects and regulates hippocampal A2AR (show ADORA2A Antibodies)-mediated signaling.
These data show functional association between GPR37, prosaposin, and GM1 ganglioside in the plasma membrane.
GPR37 knockout mice show age and sex specific improvements in olfaction, increased anxiety and depression-like behaviors.
Upregulation of Pael-R in the substantia nigra pars (show EPRS Antibodies) compacta of mice by retrograde infection induced endoplasmic reticulum (ER) stress leads to death of dopaminergic neurons.
GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs.
Data show that GPR37 overexpression can induce cellular autophagy, which may prevent the selective degeneration of GPR37-expressing neurons, as reported for Parkinson's and related neurodegenerative diseases.
Macroautophagy of the GPR37 orphan receptor (show NR1D2 Antibodies) and Parkinson disease-associated neurodegeneration
GPR37 was shown to be a component of the CASPR2 (show CNTNAP2 Antibodies)-MUPP1 (show MPDZ Antibodies) complex in brain.
GPR37 may play an important role in the pathogenesis of hepatocellular carcinoma by affecting the proliferation of HCC (show FAM126A Antibodies) cells.
Positive role of GPR37 in the proliferation of multiple myeloma cells.
GPR37 and GPR37L1 (show GPR37L1 Antibodies) are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin (show PSAP Antibodies).
results suggested that some alleles in GPR37 were related to the deleterious effect of ASD. GPR37 is associated with the dopamine transporter to modulate dopamine uptake, and regulates behavioral responses to dopaminergic drugs
results show that panneuronal expression of Parkin (show PARK2 Antibodies) substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin (show PARK2 Antibodies) degrades Pael-R and suppresses its toxicity
Glup/PACRG (show PACRG Antibodies) suppresses cell death induced by accumulation of unfolded Pael receptor and facilitates the formation of Pael-R inclusions.
Parkin (show PARK2 Antibodies)-ko/Pael-R-tg mice represents an AR-JP mouse model displaying chronic and selective loss of catecholaminergic neurons.
GPR37 surface trafficking in heterologous cells can be greatly enhanced by N-terminal truncation, coexpression with other receptors, and coexpression with syntenin-1 (show SDCBP Antibodies).
This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease.
G protein-coupled receptor 37 (endothelin receptor type B-like)
, G-protein coupled receptor CNS1
, probable G-protein coupled receptor 37
, parkin-associated endothelin B-like receptor
, Parkin-associated endothelin receptor-like receptor
, endothelin B receptor-like protein 1