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The protein encoded by GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. Additionally we are shipping GTSE1 Proteins (3) and GTSE1 Kits (2) and many more products for this protein.
Showing 10 out of 62 products:
Human Polyclonal GTSE1 Primary Antibody for FACS, IHC (p) - ABIN952659
Bublik, Scolz, Triolo, Monte, Schneider: Human GTSE-1 regulates p21(CIP1/WAF1) stability conferring resistance to paclitaxel treatment. in The Journal of biological chemistry 2010
Show all 5 references for ABIN952659
Chicken Polyclonal GTSE1 Primary Antibody for WB - ABIN2775433
Beausoleil, Villén, Gerber, Rush, Gygi: A probability-based approach for high-throughput protein phosphorylation analysis and site localization. in Nature biotechnology 2006
Human Polyclonal GTSE1 Primary Antibody for WB - ABIN526771
Cheeseman, Harry, McAinsh, Prior, Royle: Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. in Journal of cell science 2013
Study identifies GTSE1 as a biomarker for cisplatin resistance in gastric cancer cells and suggests its repressive role in cisplatin induced apoptosis making it a potential therapeutic target for better clinical management of gastric cancer patients.
GTSE1 is a microtubule plus-end tracking protein that regulates EB1 (show MAPRE2 Antibodies)-dependent cell migration.
GTSE1 is overexpressed dramatically in lung cancer patients' tissues.
Data show that G2 and S-phase-expressed 1 (GTSE1) protein, a negative regulator of p53 (show TP53 Antibodies), is required for G2 checkpoint recovery and that Plk1 (show PLK1 Antibodies) phosphorylation of GTSE1 promotes its nuclear localization.
hGTSE-1 mediated-p21(CIP1/WAF1 (show CDKN1A Antibodies)) stabilization is clearly involved in the ability of cells to counteract cytotoxicity induced by the microtubule poison paclitaxel.
GTSE-1 controls DNA damage-induced apoptosis by affecting p53 (show TP53 Antibodies) function
requires an intact nuclear export signal and functional Mdm2 (show MDM2 Antibodies) for the regulation of p53 (show TP53 Antibodies)
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
G-2 and S-phase expressed 1
, G2 and S phase-expressed protein 1
, G2 and S phase-expressed protein 1-like
, g2 and S phase-expressed protein 1-like
, protein B99 homolog
, G two S phase expressed protein 1