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GDP-Mannose 4,6-Dehydratase (GMDS) ELISA Kits

GDP-mannose 4,6-dehydratase (GMD\\\\; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. Additionally we are shipping GDP-Mannose 4,6-Dehydratase Antibodies (35) and GDP-Mannose 4,6-Dehydratase Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GMDS 218138 Q8K0C9
Anti-Rat GMDS GMDS 291095  
GMDS 2762 O60547
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Top GDP-Mannose 4,6-Dehydratase ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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More ELISA Kits for GDP-Mannose 4,6-Dehydratase Interaction Partners

Human GDP-Mannose 4,6-Dehydratase (GMDS) interaction partners

  1. Disruptions of enhancers near FOXC1 (show FOXC1 ELISA Kits) and GMDS may influence brain development.

  2. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1 (show ABCA1 ELISA Kits)), within actin filament associated protein 1 (AFAP1 (show AFAP1 ELISA Kits)) and within GDP-mannose 46-dehydratase (GMDS).

  3. These data demonstrate involvement of GMDS mutation in the progression of colorectal cancer.

  4. Fx enzyme and GDP-L-Fuc (show FUT8 ELISA Kits) Tr overexpression in the tumur tissue of colorectal cancer (CRC (show CALR ELISA Kits)) patients suggests that GDP-L-Fuc (show FUT8 ELISA Kits) transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC (show CALR ELISA Kits).

  5. GMD inhibits tankyrase 1 (show TNKS ELISA Kits) poly(ADP-ribose) polymerase (show PARP1 ELISA Kits) activity in vitro, dependent on the GMD tankyrase 1 (show TNKS ELISA Kits) binding motif. In vivo, depletion of GMD led to degradation of tankyrase 1 (show TNKS ELISA Kits), dependent on the catalytic PARP (show COL11A2 ELISA Kits) activity of tankyrase 1 (show TNKS ELISA Kits).

  6. Results indicate that GMDS regulates the formation of secondary complex II from the primary DISC independent of direct fucosylation of death receptors.

  7. Deficiency of GMDS leads to escape from natural killer cell-mediated tumor surveillance through modulation of TRAIL signaling.

GDP-Mannose 4,6-Dehydratase (GMDS) Antigen Profile

Antigen Summary

GDP-mannose 4,6-dehydratase (GMD\; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

Gene names and symbols associated with GMDS

  • GDP-mannose 4, 6-dehydratase (Gmds) antibody
  • GDP-mannose 4,6-dehydratase (GMDS) antibody
  • BC031788 antibody
  • C87208 antibody
  • GMD antibody
  • SDR3E1 antibody

Protein level used designations for GMDS

GDP-D-mannose dehydratase , GDP-mannose 4,6 dehydratase , GMD , short chain dehydrogenase/reductase family 3E, member 1

GENE ID SPECIES
218138 Mus musculus
291095 Rattus norvegicus
2762 Homo sapiens
420890 Gallus gallus
488189 Canis lupus familiaris
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