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GRIPAP1 encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). Additionally we are shipping GRIP1 Associated Protein 1 Antibodies (45) and many more products for this protein.
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results demonstrate a requirement for normal recycling endosome function in AMPAR-dependent synaptic function and neuronal connectivity in vivo, and suggest a potential role for GRASP1 in the pathophysiology of human cognitive disorders.
GRASP-1 was identified as an soluble autoantigen that has numerous coiled-coil domains throughout the protein.
Results suggest that GRASP-1 serves as a scaffold protein (show HOMER1 Proteins) to facilitate MEKK-1 (show MAP3K1 Proteins) activation of JNK (show MAPK8 Proteins) signaling in neurons.
This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms\; however, the full-length nature and biological validity of all of these variants have not been determined.
GRIP1 associated protein 1
, GRIP1-associated protein 1
, GRIP1-associated protein 1-like
, HCMV-interacting protein
, GRIP-associated protein 1