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Gap Junction Protein, beta 2, 26kDa (GJB2) ELISA Kits

GJB2 encodes a member of the gap junction protein family. Additionally we are shipping GJB2 Antibodies (90) and GJB2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GJB2 14619 Q00977
GJB2 394266 P21994
GJB2 2706 P29033
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Top GJB2 ELISA Kits at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.66 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Mouse 14.063 pg/mL 23.438-1500 pg/mL Diagramm of the ELISA kit to detect Mouse CX26with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 8 to 9 Days
$638.00
Details
Rat 9.375 pg/mL 15.625-1000 pg/mL Diagramm of the ELISA kit to detect Rat CX26with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 8 to 9 Days
$638.00
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Pig 0.1 ng/mL 5-100 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Chicken 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 8 to 9 Days
$715.00
Details
Sheep 1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$707.14
Details

More ELISA Kits for GJB2 Interaction Partners

Xenopus laevis Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. Using reconstituted hemichannels in a liposome-based transport-specific fractionation assay, we confirmed that homomeric Cx26 and Cx32 (show GJB1 ELISA Kits) and heteromeric Cx26/Cx32 (show GJB1 ELISA Kits) are permeable to GSH and other endogenous reductants.

Mouse (Murine) Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. Reduced Cx26 expression in the mature mouse cochlea may increase susceptibility to noise-induced hearing loss .

  2. mir (show MLXIP ELISA Kits)-27a was identified as an apoptotic molecule that participates in Cx26 knockout-induced apoptosis in the cochlear sensory epithelium of mice by downregulating sgk1 (show SGK1 ELISA Kits) expression

  3. Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer.

  4. Cx26-mediated intercellular communication is required for cochlear development and that deficiency of Cx26 can impair miRNA-mediated intercellular genetic communication in the cochlea, which may lead to cochlear developmental disorders

  5. presence of Cx30 (show GJB6 ELISA Kits) in the cochlea does not compensate for Cx26 loss, and the absence of both connexins from vestibular sensory epithelia is no more injurious than the absence of one of them

  6. Reciprocal positive regulation between Cx26 and PI3K/Akt (show AKT1 ELISA Kits) pathway confers acquired gefitinib resistance in non-small-cell lung carcinoma cells by promoting epithelial mesenchymal transition via a gap-junctional communication-independent manner.

  7. The inserting reconstituted gap junction Cx26 liposomes into the oocytes allowed the demonstration of intracellular/extracellular Ca(2 (show CA2 ELISA Kits)+)-regulated hemi-channel activities.

  8. Study used an inducible gene knockout technique to delete Cx26 expression in the cochlea after birth, results suggest that Cx26 deficiency may impair active cochlear amplification leading to late-onset hearing loss

  9. These results suggest that low levels of Cx26 expression throughout pregnancy and lactation, and not the physiological surge in Cx26, is sufficient for normal gland development and function.

  10. These results suggest that successful treatment of Cx26 deafness requires early intervention before the cochlea fully matures.

Human Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. Two GJB2 mutations, c.del35G with an allele frequency of 4.7 % and R32C (3.7 %) were detected in Mauritanian children with non-syndromic hearing loss.

  2. Our results showed that the GJB2 gene is a major contributor to non syndromic hearing loss in Morocco

  3. Compound heterozygous variants c.94C > T (p.R32C) and c.235delC (p.L79Cfs*3) in the GJB2 gene were identified in the two patients of an autosomal recessive non-syndromic hearing loss family, and the heterozygous GJB2 c.94C > T and c.235delC variants were identified in his unaffected father and mother, respectively.

  4. mutations detected in 35 of 156 deaf patients

  5. GJB2 gene mutations are highly prevalent in pre-lingual hearing loss patients from China. 83.64% of the 330 patients carried variations in the GJB2 gene. Seventeen different genotypes were identified. A total of 31.2% of the patients carried 2 confirmed pathogenic mutations. The frequency of c.235delC was higher than that reported previously in the Jiangsu province.

  6. GJB2 gene mutation is the most common mutation for congenital hearing loss in Chinese newborns.

  7. 48.67% of the patients were identified with hereditary hearing loss caused by mutations in GJB2, SLC26A4 (show SLC26A4 ELISA Kits), and mtDNA12SrRNA.

  8. Low frequency of GJB2 mutations in this population is indicative that other genes may be involved in nonsyndromic hearing loss in Ilam populations.

  9. Data identified two Disease-causing Genes TJP2 (show TJP2 ELISA Kits) and GJB2 in a Chinese Family with Unconditional Autosomal Dominant Nonsyndromic Hereditary Hearing Impairment.

  10. consequences of GJB2 Gene Missense Mutations

Cow (Bovine) Gap Junction Protein, beta 2, 26kDa (GJB2) interaction partners

  1. intermediate invasive status of bovine trophoblast is supported by the fact that trophoblast giant cells coexpress connexins (Cx)26, Cx32 (show GJB1 ELISA Kits), and Cx43 (show GJA1 ELISA Kits)

GJB2 Antigen Profile

Antigen Summary

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

Gene names and symbols associated with GJB2

  • gap junction protein, beta 2, 26kDa (gjb2) antibody
  • gap junction protein, beta 2, 26kDa (GJB2) antibody
  • gap junction protein, beta 2 (Gjb2) antibody
  • AI325222 antibody
  • Cnx26 antibody
  • connexin-26 antibody
  • CX26 antibody
  • CXN-26 antibody
  • DFNA3 antibody
  • DFNA3A antibody
  • DFNB1 antibody
  • DFNB1A antibody
  • Gjb-2 antibody
  • GJB2 antibody
  • HID antibody
  • KID antibody
  • MGC53062 antibody
  • NSRD1 antibody
  • PPK antibody

Protein level used designations for GJB2

gap junction protein, beta 2, 26kDa , connexin 26 , connexin 29 , gap junction membrane channel protein beta 6 , gap junction protein, beta 2, 26kDa (connexin 26) , connexin-26 , gap junction beta-2 protein , gap junction membrane channel protein beta 2 , gap junction channel protein connexin 26 , connexin26 , gap junction protein beta 2 , connexin 26 protein , cx26

GENE ID SPECIES
380170 Xenopus laevis
467220 Pan troglodytes
14619 Mus musculus
394266 Rattus norvegicus
100379528 Cavia porcellus
2706 Homo sapiens
403570 Canis lupus familiaris
407154 Bos taurus
443345 Ovis aries
704224 Macaca mulatta
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