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C16ORF53 (PA1) is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 [PubMed 17500065]).[supplied by OMIM, May 2008].. Additionally we are shipping Gastrin Antibodies (132) and Gastrin Kits (88) and many more products for this protein.
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PTHLH is a gastrin-regulated growth factor that might contribute to gastric epithelial cell homeostasis.
Gastrin is expressed in both in (show INS Proteins)sulin(+) and somatostatin(+) cells in adults with type 2 diabetes.
Gastrin induced ABCG2 expression by activating NF-kappaB (show NFKB1 Proteins) and thereby modulated the side population proportion, tumor cell metastatic potential and invasion activity in pancreatic cancer.
CTGF (show CTGF Proteins) is overexpressed in gastric cancer and adjacent tissue compared to normal gastric tissue. Gastrin induces expression of CTGF (show CTGF Proteins) in gastric epithelial cells.
Data show that 6 of 20 primary pancreatic neuroendocrine tumors (PNETs) had positive staining for multiple hormones gastrin, insulin (show INS Proteins), glucagon (show GCG Proteins), and somatostatin (show SST Proteins), and positive expression of 1 or more hormones was found in 9 of 12 nonfunctioning PNETs [NF-PNETs]) patients.
Gastrin role in gastric epithelial homeostasis and gastric carcinogenesis
Results suggest a role for Toll-like receptor 4 (show TLR4 Proteins) in gastric acid regulation and that the Toll-like receptor 4 (TLR4 (show TLR4 Proteins)) +896 and +1196 wild type homozygozity increases peptic ulcer risk via gastrin secretion.
Serum pepsinogens I (PGI (show BGN Proteins)) and II (PGII (show DCN Proteins)), gastrin 17 (G-17), and antibodies against whole H. pylori, or cytotoxin-associated gene A (CagA (show S100A8 Proteins)) antigen among 309 consecutive patients, were measured.[Pepsinogen I, Gastrin 17]
treatment with gastrin, a CCK2R (show CCKBR Proteins) agonist, stimulated the secretion of GLP-1 (show GCG Proteins), and that this effect was likely due to increased expression of proglucagon (show GCG Proteins) and PCSK1 (show PCSK1 Proteins) (also known as prohormone convertase 3 (PC3 (show PCSK1 Proteins) gene)).
Gastrin stimulates MMP-1 (show MMP1 Proteins) expression in gastric epithelial cells and stimulates cell migration.
Renal-selective silencing of Gast by the renal subcapsular injection of Gast siRNA in BALB/c mice decreases renal dopamine production and increases blood pressure.
Gastrin is expressed in insulin (show INS Proteins) secreting cells of adult diabetic mice.
Ihh (show IHH Proteins) signaling mediates gastrin-induced proliferation of epithelial cells in stomachs of adult mice.
mouse corneal afferent sensory neurons expressed CCK and GAST, and the CCK1R receptors.
Data indicate that epithelial Gli2 expression was sufficient to stimulate Il-1beta (show IL1B Proteins) expression, repress Gast gene expression and increase proliferation, leading to antral hyperplasia.
Initiation of antral gastric cancer is associated with progressive epigenetic silencing of TFF1 (show TFF1 Proteins), which can be suppressed by the hormone gastrin.
Regulation of mouse gastrin gene in vivo. Mechanisms involved in transcriptional control of the gastrin gene.
RegI and gastrin may synergistically regulate gastric mucosal proliferation during certain pathological settings like wound healing
Serum gastrin decreased significantly in the cholesterol gallstone groups compared to the control group.
C16ORF53 (PA1) is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007
, PAXIP1-associated glutamate-rich protein 1
, PAXIP1-associated protein 1
, PTIP-associated 1 protein
, PTIP-associated protein 1
, glutamate-rich coactivator associated with SRC1
, glutamate-rich coactivator interacting with SRC1/NCOA1