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Receptor for gastrin releasing peptide (GRP). Additionally we are shipping GRPR Antibodies (55) and GRPR Kits (3) and many more products for this protein.
Showing 6 out of 6 products:
ablating GRP (show UCMA Proteins) receptor-expressing neurons eliminated basal and hypoxia-induced sighing, but left breathing otherwise intact initially
Together, we define the respective function of NMBR and GRPR in itch transmission, and reveal an unexpected relationship not only between the two receptors but also between the two populations of interneurons in itch signaling.
BNP-NPRA (show NPR1 Proteins) signaling is involved in both itch and pain and does not function upstream of the GRP (show UCMA Proteins)-GRPR dedicated neuronal pathway.
The present results suggest that BB2 receptor-expressing spinal neurons transmit herpes-associated itch by BB2 receptor-independent signaling.
spinal GRPr and NMBr independently drive itch neurotransmission in mice.
GRPR and stathmin (show STMN1 Proteins) control in opposite directions both cued fear extinction and neural activities of the amygdala and prefrontal cortex
Gastrin-releasing peptide receptor mediates chemotaxis in neutrophils, and may be an alternative chemotactic receptor playing a role in the pathogenesis of inflammatory disorders.
The data suggest that opioid-induced itch is an active process concomitant with but independent of opioid analgesia, occurring via the unidirectional cross-activation of GRPR signaling by MOR1D heterodimerization
We propose that deletion of GRPR leads to the induction of depression-like behavior which is paralleled by dysregulation of amygdala gene expression, potentially resulting from deficient light-induced corticosterone release in GRPR-knockout mice
GRP-R-deficient mice showed no significant different in risk assessment behavior of conventional anxiwety parameters, so GRP-R may not impact this anxiety or emotional behavior.
Expression of Gastrin-Releasing Peptide Receptor in Breast Cancer and Its Association with Pathologic, Biologic, and Clinical Parameters
Our results suggest that, similar to what happens in neutrophils, gastrin-releasing peptide (show GRP Proteins) is a migratory, rather than a proliferative, stimulus, for non-small cell lung carcinoma cells, indicating a putative role for gastrin-releasing peptide (show GRP Proteins) and gastrin-releasing peptide receptor in metastasis
GRP-R regulates glucose metabolism in neuroblastoma (show ARHGEF16 Proteins) by modulating HIF-1alpha (show HIF1A Proteins), PDK4 (show PDK4 Proteins) and PDP2 (show PDP2 Proteins).
BBS (show BBS2 Proteins) caused a significant increase in Shh (show SHH Proteins) gene transcription and protein secretion that was dependent on BBS (show BBS2 Proteins)-induced GPCR (show NMUR1 Proteins)/Galphaq (show GNAQ Proteins)-//Rho mediated activation of nuclear factor kappaB (NFkappaB (show NFKB1 Proteins)), which can stimulate a NF-kappaB (show NFKB1 Proteins) response element in the Shh (show SHH Proteins) gene promoter
No association of 16 GRP (show LSM4 Proteins) and 7 GRPR variants were found with agoraphobia with/without panic disorder.
GRPR is highly expressed in epidermoid carcinoma of the anal canal, suggesting this receptor might have a role in anal carcinogenesis.
a key mechanism for GRPR-regulated colon cancer cell migration through the Galpha13 (show GNA13 Proteins)-PRG-RhoA (show RHOA Proteins)-ROCK pathway.
GRPR expression was more pronounced in an advanced-stage lung cancer
integrin ss1 subunit critically regulates GRP-R-mediated neuroblastoma (show ARHGEF16 Proteins) cell migration and invasion
Elevated buccal GRPR espression was significantly associated with squamous cell carcinoma of the head and neck.
Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
gastrin-releasing peptide receptor
, gastrin-releasing peptide receptor-like
, GRP-preferring bombesin receptor
, bombesin receptor