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anti-General Transcription Factor III (GTF2I) Antibodies

GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. Additionally we are shipping GTF2I Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GTF2I 14886 Q9ESZ8
GTF2I 353256 Q5U2Y1
GTF2I 2969 P78347
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Top anti-GTF2I Antibodies at antibodies-online.com

Showing 10 out of 119 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-GTF2I Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-GTF2I Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GTF2I Antibody (C-term) in Y79 cell line lysates (35 µg/lane). GTF2I (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-GTF2I  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2There is BioGPS gene expression data showing that GTF2I is expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Mouse Un-conjugated IF, WB Western blot analysis of TFII-I on HeLa cell lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of anti-TFII-I. Immunofluorescent staining of FHS cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of GTF2I Antibody (C-term) (ABIN390868) in Y79 cell line lysates (35 µg/lane). GTF2I (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GTF2I Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from LOVO cells, using TFII-I (Phospho-Tyr248) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Small Intestine (formalin-fixed, paraffin-embedded) stained with GTF2I antibody ABIN364488 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Prostate (formalin-fixed, paraffin-embedded) stained with GTF2I antibody ABIN364488 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF, WB Fluorescent image of Hela cell stained with GTF2I Antibody (N-term).Hela cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with GTF2I primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃). GTF2I immunoreactivity is localized to Nucleus significantly. GTF2I Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GTF2I antibody detected the GTF2I protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

GTF2I Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GTF2I Antibodies

  1. Chicken Polyclonal GTF2I Primary Antibody for IHC, WB - ABIN2777491 : Morris, Mervis, Hobart, Gregg, Bertrand, Ensing, Sommer, Moore, Hopkin, Spallone, Keating, Osborne, Kimberley, Stock: GTF2I hemizygosity implicated in mental retardation in Williams syndrome: genotype-phenotype analysis of five families with deletions in the Williams syndrome region. in American journal of medical genetics. Part A 2003 (PubMed)

  2. Dog (Canine) Polyclonal GTF2I Primary Antibody for IHC, WB - ABIN2777492 : Desgranges, Ahn, Lazebnik, Ashworth, Lee, Pestell, Rosenberg, Prives, Roy: Inhibition of TFII-I-dependent cell cycle regulation by p53. in Molecular and cellular biology 2005 (PubMed)

  3. Dog (Canine) Monoclonal GTF2I Primary Antibody for IF, WB - ABIN968264 : Yang, Desiderio: BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)

  4. Human Polyclonal GTF2I Primary Antibody for EIA, WB - ABIN453078 : Roy, Du, Gregor, Novina, Martinez, Roeder: Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. in The EMBO journal 1998 (PubMed)

  5. Chicken Polyclonal GTF2I Primary Antibody for WB - ABIN2787508 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)

More Antibodies against GTF2I Interaction Partners

Mouse (Murine) General Transcription Factor III (GTF2I) interaction partners

  1. found a highly conserved DNA element, common to a set of genes regulated by TFII-I, and identified and validated novel in vivo neuronal targets of this protein affecting the PI3K and TGFbeta (show TGFB1 Antibodies) signaling pathways

  2. GTF2IRD2 (show GTF2IRD2 Antibodies) has evolved as a regulator of GTF2IRD1 (show GTF2IRD1 Antibodies) and TFII-I; inhibiting their function by direct interaction and sequestration into inactive nuclear zones.

  3. data support the hypothesis that upregulation of TFII-I factors leads to activation of a specific group of developmental genes during mESC differentiation

  4. GTF2I duplication results in separation anxiety in mice and humans

  5. In order to clarify the involvement of GTF2I in neurocognitive function, especially social behavior, we have developed and characterized Gtf2i-deficient mice.

  6. Results suggest that DJ-1 (show PARK7 Antibodies) together with TFII-I operate in concert to cope with various insults and to sustain pancreatic beta-cell function.

  7. behavioral characterization of heterozygous mice with a deletion of the first 140 amino-acids of TFII-I.

  8. data demonstrate that TFII-I, through a Src (show SRC Antibodies)-dependent mechanism, reversibly translocates from the cytoplasm to the nucleus, leading to the transcriptional activation of growth-regulated genes

  9. acts as a transcriptional cofactor for the SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 (show PIAS2 Antibodies)

  10. TFII-I has a role in regulating immunoglobulin promoter activity

Human General Transcription Factor III (GTF2I) interaction partners

  1. The authors found that human adenovirus 5 infection or ectopic E4-ORF3 (show ASZ1 Antibodies) expression leads to SUMOylation of TFII-I that precedes a rapid decline in TFII-I protein levels.

  2. A novel interaction between TFII-I and Mdm2 (show MDM2 Antibodies) with a negative effect on TFII-I transcriptional activity has been documented.

  3. Copy-number variation in the general transcription factor gene, GTF2I is associated with gene-dose-dependent anxiety in mouse models and in both Williams syndrome and Dup7.

  4. show that SUMOylation is critical for TFII-I to promote cell proliferation and colony formation. Our findings contribute to understanding the role of SUMOylation in liver cancer development

  5. Study demonstrates a significant association between SLE in Chinese Han population and the GTF2I rs117026326 T allele/GTF2IRD1 (show GTF2IRD1 Antibodies) rs4717901 C allele.

  6. Rather than contributing positively to promoter activity, a putative initiator element at the transcription start site acts as a target for negative regulation imposed on the L4P promoter of human adenovirus Type 5 by cellular TFII-I.

  7. Findings implicate the GTF2I gene in the neurogenetic basis of social communication and social anxiety, both in Williams syndrome and among individuals in healthy populations

  8. TFII-I bridges Proliferating Cell Nuclear Antigen (show PCNA Antibodies) and Polzeta to promote Translesion synthesis

  9. The GTF2I rs117026326 polymorphism is associated with anti-SSA (show TRIM21 Antibodies)-positive primary Sjogren's syndrome.

  10. A proportion of this transcriptional dysregulation is caused by dosage imbalances in GTF2I, which encodes a key transcription factor at 7q11.23 that is associated with the LSD1 (show KDM1A Antibodies) repressive chromatin complex and silences its dosage-sensitive targets.

GTF2I Antigen Profile

Protein Summary

This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.

Gene names and symbols associated with GTF2I

  • general transcription factor IIi (gtf2i) antibody
  • general transcription factor II I (Gtf2i) antibody
  • general transcription factor IIi (GTF2I) antibody
  • 6030441I21Rik antibody
  • BAP-135 antibody
  • BAP135 antibody
  • BTKAP1 antibody
  • DIWS antibody
  • Gtf2ird1 antibody
  • GTFII-I antibody
  • IB291 antibody
  • SPIN antibody
  • TFII-I antibody
  • WBS antibody
  • WBSCR6 antibody

Protein level used designations for GTF2I

BTK-associated protein 135 , Bruton tyrosine kinase-associated protein 135 , general transcription factor II-I , GTFII-I , TFII-I , BTK-associated protein, 135kD , SRF-Phox1-interacting protein , Williams-Beuren syndrome chromosome region 6 , general transcription factor II, i

GENE ID SPECIES
549986 Xenopus (Silurana) tropicalis
14886 Mus musculus
353256 Rattus norvegicus
2969 Homo sapiens
417486 Gallus gallus
479714 Canis lupus familiaris
534669 Bos taurus
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