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The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Additionally we are shipping Glucagon-Like Peptide 2 Receptor Antibodies (77) and Glucagon-Like Peptide 2 Receptor Proteins (10) and many more products for this protein.
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Among young and healthy adults, GLP-1 (show GCG ELISA Kits) levels are strongly and independently related to body fat mass especially in men, but not body mass index or waist circumference.
Glucagon (show GCG ELISA Kits) circulates in patients without a pancreas and glucose stimulation of the gastrointestinal tract elicits significant hyperglucagonemia in these patients.
There is minor contribution of endogenous GLP-1 and GLP-2 to postprandial lipemia in obese men.
Data suggest that endocrine responses differ between jejunal and gastric enteral feeding, with higher peak plasma CCK (cholecystokinin), PYY (peptide YY), and GLP-1/2 (glucagon-like peptides 1/2) concentrations being attained after jejunal feeding.
Data suggest that capsaicin, an appetite suppressant dietary supplement (here, administered via intraduodenal infusion), does not act via alteration of secretion of satiety hormones GLP-1 (GLP-1) and PYY (peptide YY).
Data show that NCI-H716 cells were immunostained for tumor necrosis factor (show TNF ELISA Kits) receptor TNFR1 (show TNFRSF1A ELISA Kits), and TNFalpha (show TNF ELISA Kits) treatment enhances glucagon-like peptide-1 (GLP-1 (show GCG ELISA Kits)) secretion.
active GLP-1 (show GCG ELISA Kits) produced in the islet stimulates cholecystokinin (show CCK ELISA Kits) production and secretion in a paracrine manner via cyclic AMP (show APRT ELISA Kits) and CREB (show CREB1 ELISA Kits).
Data suggest that secretion of insulin (show INS ELISA Kits) and glucagon (show GCG ELISA Kits) is up-regulated in subjects with type 2 diabetes with dyssomnia as compared to subjects with type 2 diabetes without dyssomnia; those with dyssomnia exhibit prehypertension and insulin (show INS ELISA Kits) resistance.
Data suggest plasma GLP1 (glucagon-like peptide 1) and PYY (peptide YY) can be regulated by digestion-resistant diet factors; intake of soluble dietary fiber (prebiotic Fibersol-2) in a tea with meal up-regulated plasma GLP1/PYY and decreased hunger.
Glucagon (show GCG ELISA Kits) has emerged as a key hormone for the regulation of glucose homeostasis and for development of type 2 diabetes. [Review]
Results suggest that GLP-2 (show GCG ELISA Kits) protected and improved memory function in LPS (show TLR4 ELISA Kits)-treated mice, and also had anxiolytic effects due to changes in the 5-HT (show DDC ELISA Kits) system.
Report gastrointestinal GLP-2 receptor andl limited utility of GLP-2 in the management of inflammatory intestinal disorders.
GLP-2 (show GCG ELISA Kits) plays a key physiological role in the control of hepatic glucose production through activating PI3K-dependent modulation of membrane excitability and nuclear transcription of POMC (show POMC ELISA Kits) neurons in the brain.
Data suggest a role for endogenous GLP2 (glucagon-like peptide-2 (show GCG ELISA Kits)) and GLP2R in adaptation of mucosa of duodenum and jejunum to high-fat diet; results suggest dysregulation of GLP2/GLP2R signaling in obesity due to prolonged high-fat diet.
The data indicated that CNS GLP-2 receptor plays a physiological role in the control of feeding behavior and gastric emptying and that this is mediated probably through the melanocortin system.
Data suggest that the Vip (show Vip ELISA Kits) gene is not required for induction of a gene expression program linked to small bowel growth after enhancement of GLP-2 receptor signaling.
Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis
Data show that the GLP-2R is expressed by inhibitory and excitatory neurons, and inhibits the muscle contractility likely by decreasing cholinergic neurotransmission and increasing nitric oxide production.
GLP-2R is not critical for the stimulation/suppression of glucagon (show GCG ELISA Kits) secretion or glucose homeostasis in normal or lean diabetic mice. In obese mice GLP-2R signaling mediates the normal islet adaptive response required to maintain glucose homeostasis.
Glucagon-like peptide-2 (show GCG ELISA Kits) potentiates L-type voltage-gated Ca(2 (show CA2 ELISA Kits)+) channels activity through activating cAMP-dependent protein kinase A signaling, partially stimulating glucose uptake by primary cultured hippocampal neurons.
data demonstrate that cattle express proglucagon (show GCG ELISA Kits) and glucagon-like peptide 2 receptor mRNA primarily in small intestinal and colon tissues
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
glucagon-like peptide 2 receptor
, glicentin-related polypeptide
, glucagon-like peptide 1
, glucagon-like peptide 2
, GLP-2 receptor
, G protein-coupled receptor GLP2R
, glucagon-like peptide-2 receptor