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The protein encoded by GNPDA2 is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Additionally we are shipping Glucosamine-6-Phosphate Deaminase 2 Proteins (6) and Glucosamine-6-Phosphate Deaminase 2 Kits (3) and many more products for this protein.
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Human Polyclonal GNPDA2 Primary Antibody for EIA, IF - ABIN499898
Wolosker, Kline, Bian, Blackshaw, Cameron, Fralich, Schnaar, Snyder: Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998
Data show that SNPs in SEC16B (show SEC16B Antibodies) and TMEM18 (show TMM18 Antibodies) were significantly associated with obesity, and the SNPs in GNPDA2, BDNF (show BDNF Antibodies), FAIM2 (show FAIM2 Antibodies) and MC4R (show MC4R Antibodies) were marginally associated with obesity in Japanese.
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
glcN6P deaminase 2
, glucosamine-6-phosphate isomerase 2
, glucosamine-6-phosphate isomerase SB52
, GNPDA 2