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anti-Glucosidase, Alpha, Acid (GAA) Antibodies

GAA encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Additionally we are shipping GAA Kits (16) and GAA Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAA 367562 Q6P7A9
GAA 14387 P70699
GAA 2548 P10253
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Top anti-GAA Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB GAA Antibody (N-term) (ABIN656475) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GAA Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate Rabbit Anti-GAA Antibody ,Paraffin Embedded Tissue: Human Lung Tissue 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged GAA is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.96 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IHC (p), WB Anti-GAA antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101643 dilution 1:50. 100 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 200 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB GAA antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$347.60
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$347.60
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$356.40
Details

GAA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) , ,



Mouse (Murine) , ,



Human , ,
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Top referenced anti-GAA Antibodies

  1. Human Polyclonal GAA Primary Antibody for IHC (p), WB - ABIN656475 : Aoyama, Ozer, Demirkol, Ebara, Murase, Podskarbi, Shin, Gokcay, Okubo: Molecular features of 23 patients with glycogen storage disease type III in Turkey: a novel mutation p.R1147G associated with isolated glucosidase deficiency, along with 9 AGL mutations. in Journal of human genetics 2009 (PubMed)
    Show all 2 references for ABIN656475

  2. Human Monoclonal GAA Primary Antibody for ELISA, WB - ABIN560974 : Xiao, Westbroek, Motabar, Lea, Hu, Velayati, Zheng, Southall, Gustafson, Goldin, Sidransky, Liu, Simeonov, Tamargo, Ribes, Matalonga, Ferrer, Marugan: Discovery of a novel noniminosugar acid ? glucosidase chaperone series. in Journal of medicinal chemistry 2012 (PubMed)
    Show all 2 references for ABIN560974

More Antibodies against GAA Interaction Partners

Mouse (Murine) Glucosidase, Alpha, Acid (GAA) interaction partners

  1. GAA deficiency results in reduced mTORC1 activation that is partly responsible for the skeletal muscle wasting phenotype and can be amerliorated by leucine supplementation.

  2. Results describe the inhibitory effects of Chana series chalcone derivatives on the activities of alpha-glucosidase (show AGLU Antibodies) and DPP-4 (show DPP4 Antibodies), and on adipocyte differentiation.

  3. Power and torque did not change with age in control animals, but declined significantly in acid 1-4 alpha-glucosidase (show AGLU Antibodies) knockout mice in three age groups.

  4. These studies suggest that hyase enhances penetration of enzyme into the tissues including muscle during ERT (show ELF3 Antibodies) and therefore hyase pretreatment may be important in treating Pompe disease.

Human Glucosidase, Alpha, Acid (GAA) interaction partners

  1. Study reports on the clinical, biochemical, morphological, muscle imaging, and genetic findings of six adult Pompe patients from five unrelated families with the c.-32-13T>G GAA gene mutation in homozygous state. All patients had decreased GAA activity and elevated creatine kinase levels.

  2. glycogen (show GYS1 Antibodies) storage disease type II is caused by deficiency of GAA activity resulting from mutation of GAA gene

  3. RT-PCR followed by DNA sequence analysis of patients with Pompe disease revealed new variant in GAA gene resulting in aberrant splicing event.

  4. Findings indicate that GAA c.2238G > C (p.W746C) novel mutation is the most common mutation in mainland Chinese late-onset Pompe patients, as observed in Taiwanese patients expanding the genetic spectrum of the disease.

  5. this study shows several alterations distributed along the GAA gene in a sample of Brazilian families.

  6. GAA deficiency results in reduced mTORC1 activation that is partly responsible for the skeletal muscle wasting phenotype and can be amerliorated by leucine supplementation.

  7. The phenotype LO-GSDII with GAA mutation in the North of Italy seems not significantly different from other LO-GSDII populations in Europe or the USA.

  8. Data shows the largest informative family with late-onset Pompe disease described in the literature showing a peculiar complex set of mutations of GAA gene that may partially elucidate the clinical heterogeneity of this family.

  9. 7 of 27 in: Gene. 2014 Mar (show IRF1 Antibodies) 1;537(1) Novel GAA sequence variant c.1211 A>G reduces enzyme activity but not protein expression in infantile and adult onset Pompe disease.

  10. This study demonstrates that the c.-32-13T>G mutation of GAA gene abrogates the binding of the splicing factor (show SLU7 Antibodies) U2AF65 (show U2AF59 Antibodies) to the polypyrimidine tract of exon 2 and that several splicing factors affect exon 2 inclusion.

GAA Antigen Profile

Protein Summary

This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with GAA

  • glucosidase, alpha, acid (Gaa) antibody
  • glucosidase, alpha; acid (GAA) antibody
  • E430018M07Rik antibody
  • LYAG antibody

Protein level used designations for GAA

acid (Pompe disease, glycogen storage disease type II) , acid alpha-glucosidase , acid maltase , glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) , lysosomal alpha-glucosidase , aglucosidase alfa

GENE ID SPECIES
367562 Rattus norvegicus
14387 Mus musculus
2548 Homo sapiens
483352 Canis lupus familiaris
280798 Bos taurus
100173365 Pongo abelii
Selected quality suppliers for anti-GAA (GAA) Antibodies
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