GAA antibody (AA 851-952)

Catalog No. ABIN560974

This Mouse Monoclonal antibody specifically detects GAA in WB and ELISA. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for GAA antibody (AA 851-952) (ABIN560974)

Target: GAA (Glucosidase, Alpha, Acid (GAA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GAA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3C6

Product Details anti-GAA Antibody

Binding Specificity: AA 851-952

Purpose: Mouse monoclonal antibody raised against a partial recombinant GAA.

Sequence: GEARGELFWD DGESLEVLER GAYTQVIFLA RNNTIVNELV RVTSEGAGLQ LQKVTVLGVA TAPQQVLSNG VPVSNFTYSP DTKVLDICVS LLMGEQFLVS WC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GAA (AAH40431, 851 a.a. ~ 952 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GAA antibody (ABIN560974)

Xiao, Westbroek, Motabar, Lea, Hu, Velayati, Zheng, Southall, Gustafson, Goldin, Sidransky, Liu, Simeonov, Tamargo, Ribes, Matalonga, Ferrer, Marugan: "Discovery of a novel noniminosugar acid ? glucosidase chaperone series." in: Journal of medicinal chemistry, Vol. 55, Issue 17, pp. 7546-59, (2012) (PubMed).

Cheray, Petit, Forestier, Karayan-Tapon, Maftah, Jauberteau, Battu, Gallet, Lalloué: "Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells." in: Cancer letters, Vol. 312, Issue 1, pp. 24-32, (2011) (PubMed).

Target Details for GAA

Target: GAA (Glucosidase, Alpha, Acid (GAA))

Alternative Name: GAA

Background: Full Gene Name: glucosidase, alpha, acid
Synonyms: LYAG

Gene ID: 2548

Pathways: Cellular Glucan Metabolic Process