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Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c Proteins (GRIN2C)

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. Additionally we are shipping GRIN2C Antibodies (64) and GRIN2C Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GRIN2C GRIN2C 24411 Q00961
GRIN2C 2905 Q14957
GRIN2C 14813 Q01098
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Top GRIN2C Proteins at antibodies-online.com

Showing 5 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

GRIN2C Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) Interaction Partners

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) interaction partners

  1. Findings indicate that SNPs in the GRIN2C gene is associated with altered cue-induced brain activation that is related to craving for alcohol and relapse risk.

  2. these findings highlight the isoform-specific structural and functional differences within the 14-3-3 (show YWHAQ Proteins) family of proteins, which determine GluN2C binding and its essential role in targeting the receptor to the cell surface

  3. NMDARs have a dual role during erythropoiesis, supporting survival of polychromatic erythroblasts and contributing to the Ca(2 (show CA2 Proteins)+) homeostasis from the orthochromatic erythroblast stage to circulating red blood cells.

  4. The major depression subjects exhibited significantly higher expression levels of the NMDA receptor subunit genes GRIN2C.

  5. Reduction in NR1 (show GRIN1 Proteins) and NR2C in the DLPFC of people with schizophrenia may lead to altered NMDAR (show GRIN1 Proteins) stoichiometry and provides compelling evidence for an endogenous NMDAR (show GRIN1 Proteins) deficit in schizophrenia.

  6. TNFalpha (show TNF Proteins) significantly upregulates NMDA-R2C mRNA expression, in differentiated, confluent, normal keratinocytes but not in involved or uninvolved psoriatic keratinocyte monolayers

  7. Functional compensation could occur to counteract the loss of one allele in GRIN2C and GRIN3 (show GPRIN3 Proteins) family genes.

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) interaction partners

  1. Tuberless heterozygote Tsc1 (show TSC1 Proteins)+/- mice show functional up-regulation of cortical GluN2C receptors in an mTOR (show FRAP1 Proteins)-dependent manner, exhibit recurrent, unprovoked seizures during early postnatal life, that can be treated with GluN2C antagonists.

  2. low rectification normally observed in the nucleus reticularis of the thalamus is due to NR2C

  3. No differences in expression of NR2A (show GRIN2A Proteins), NR2C or NR2D (show GRIN2D Proteins) are found in any brain region examined during ethanol consumption and acute ethanol withdrawal.

  4. Study shows that the NR2C and Tiam1 (show TIAM1 Proteins) maturation genes are synergistically controlled by the activity-dependent induction of Etv1 (show ETV1 Proteins).

  5. Findings suggest a unique role of NR2C-containing receptors in associative and executive learning. NR2C knockout mice were found to exhibit deficits in fear acquisition and working memory.

  6. indicate that SNX27 (show SNX27 Proteins) may function to regulate endocytosis and/or endosomal sorting of NR2C

  7. Expression of GluRepsilon 3 is essential for postsynaptic localization and protein stability of the GluRzeta1 (show GRIN1 Proteins) subunit.

  8. The spiny stellate neurons of barrel cortex layer 4 functionally express NR2C subunits; this is the likely explanation for their ability to generate large NMDAR (show GRIN1 Proteins)-mediated EPSPs that are effective at resting potential, without previous depolarization.

  9. results show that the NR2C by NR2B (show GRIN2B Proteins) subunit exchange in mice affects ACh (show FGFR3 Proteins) content in two target areas of the nucleus basalis

  10. Results suggest that the replacement of subunit NR2C by NR2B (show GRIN2B Proteins) in juvenile mice increases anxiety- and fear-related behaviors possibly due to changes in frontal cortex serotonin and periaqueductal grey acetylcholine levels.

GRIN2C Protein Profile

Protein Summary

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).

Gene names and symbols associated with GRIN2C

  • N-methyl-D-aspartate receptor subunit 2C (GRIN2C)
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C)
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2C (grin2c)
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2C (Grin2c)
  • glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c)
  • GluN2C protein
  • GRIN2C protein
  • il-12rb2.b protein
  • il12rb2l protein
  • NMDAR2C protein
  • NR2C protein

Protein level used designations for GRIN2C

glutamate receptor, ionotropic, N-methyl D-aspartate 2C , interleukin 12 receptor beta 2.b , interleukin 12 receptor, beta 2a, like , N-methyl-D-aspartate receptor subunit 2C , ionotropic glutamate receptor subunit NR2C , glutamate [NMDA] receptor subunit epsilon-3-like , N-methyl D-aspartate receptor subtype 2C , NMDA glutamate receptor , NMDAR2C , glutamate [NMDA] receptor subunit epsilon-3 , glutamate receptor ionotropic, NMDA 2C , glutamate receptor, ionotropic, NMDA2C , GluRepsilon3

GENE ID SPECIES
699216 Macaca mulatta
778441 Taeniopygia guttata
100003342 Danio rerio
454868 Pan troglodytes
100126608 Xenopus laevis
100496638 Xenopus (Silurana) tropicalis
24411 Rattus norvegicus
2905 Homo sapiens
100721967 Cavia porcellus
100515684 Sus scrofa
483302 Canis lupus familiaris
535158 Bos taurus
431090 Gallus gallus
14813 Mus musculus
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