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anti-Glutathione Peroxidase 4 (GPX4) Antibodies

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Additionally we are shipping Glutathione Peroxidase 4 Kits (10) and Glutathione Peroxidase 4 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPX4 2879 P36969
GPX4 625249 O70325,Q91XR9
GPX4 29328 P36970,Q91XR8
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Top anti-Glutathione Peroxidase 4 Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185669 (0.1µg/ml) staining of Human Testis lysate (35µg protein in... ABIN185669 (0.3µg/ml) staining of paraffin embedded Human Testis. Micr... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Guinea Pig Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IP, ELISA 100 μL Log in to see 2 to 3 Days
$367.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with GPX4at 2... Antibody (0.1 µg/ml) staining of Human Testis lysate (35 µg protein in... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, IP Anti-GPX4 / MCSP antibody IHC staining of human testis. Immunohistoche... 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with GPX4 ant... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$610.50
Details

GPX4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-Glutathione Peroxidase 4 Antibodies

  1. Guinea Pig Polyclonal GPX4 Primary Antibody for EIA, WB - ABIN401375 : Nam, Nakamuta, Kurohmaru, Hayashi: Cloning and sequencing of the mouse cDNA encoding a phospholipid hydroperoxide glutathione peroxidase. in Gene 1997 (PubMed)
    Show all 7 references for ABIN401375

  2. Human Polyclonal GPX4 Primary Antibody for IHC, ELISA - ABIN185669 : Su, Novoselov, Sun, Moustafa, Zhou, Oko, Hatfield, Gladyshev: Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation. in The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for ABIN185669

  3. Cow (Bovine) Polyclonal GPX4 Primary Antibody for EIA, IHC (p) - ABIN374711 : Papp, Lu, Bolderson, Boucher, Singh, Holmgren, Khanna: SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress. in Antioxidants & redox signaling 2010 (PubMed)
    Show all 2 references for ABIN374711

  4. Human Polyclonal GPX4 Primary Antibody for IHC, WB - ABIN2787700 : Peters, Chatterjee, Hayes, Schoen, Wang, Chanock, Foster: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008 (PubMed)

More Antibodies against Glutathione Peroxidase 4 Interaction Partners

Human Glutathione Peroxidase 4 (GPX4) interaction partners

  1. One SNP (rs3746162) in GPX4 was significantly associated with bladder cancer recurrence after transurethral resection.

  2. Hepatitis C virus (HCV) induces oxidative stress but controls it tightly by inducing ROS (show ROS1 Antibodies) scavengers. Among these, GPx4 plays an essential role in the HCV life cycle.

  3. GPX1 (show GPX1 Antibodies), GPX3 (show GPX3 Antibodies), and GPX4 genes may play a role in clear cell renal cell carcinoma (show MOK Antibodies) cancerogenesis.

  4. polymorphism of gene of glutathione peroxidase (show GPX1 Antibodies) predisposes to more severe affection of liver and progression of chronic hepatitis C.

  5. GPx4 is essential for maintaining oxidative homeostasis and keeping defense against oxidative stress in conjunctival epithelial cells.

  6. Identification of truncating mutations in GPX4 in two families affected with Sedaghatian-type spondylometaphyseal dysplasia.

  7. A membrane glycoprotein (show CD86 Antibodies) GPX4 was shown to play a significant role in gamete interactions.

  8. Erythrocyte glutathione peroxidase (show GPX1 Antibodies) activity is modified by single nucleotide polymorphisms in SEPP1 (show SEPP1 Antibodies), GPX4 and GPX1 (show GPX1 Antibodies) and by estrogens.

  9. neither CYBB (show CYBB Antibodies) nor GPX4 are major genetic determinants of diabetic nephropathy, but nevertheless, they could modulate in a gender-specific manner the risk for renal disease in patients with type 1 diabetes.

  10. Methamphetamine increases oxidative stress by reducing GPx1 (show GPX1 Antibodies)/4 levels, and this can be reversed with addition of selenium.

Mouse (Murine) Glutathione Peroxidase 4 (GPX4) interaction partners

  1. Phospholipid hydroperoxide glutathione peroxidase (show GPX1 Antibodies) is involved in the maintenance of male fertility under cryptorchidism in mice

  2. dramatic motor neuron degeneration (show CLN8 Antibodies) and paralysis induced by Gpx4 ablation suggest that ferroptosis inhibition by GPX4 is essential for motor neuron health and survival in vivo

  3. The lack of catalytic activity is the major reason for the embryonic lethality of Gpx4 knockout mice.

  4. Homozygous expression of Gpx4 with a targeted substitution of selenocysteine to serine causes early embryonic death as expected but, unexpectedly, male subfertility in heterozygous mice.

  5. GPx4 suppresses the increase in the VEGF-A (show VEGFA Antibodies) protein level, which occurs during the development of pathological CNV, thus partly explaining the protective effect of GPx4 against CNV.

  6. Inducible disruption of Gpx4 causes acute renal failure and early death in an Alox15 (show ALOX15 Antibodies)-independent manner

  7. A membrane glycoprotein (show CD86 Antibodies) GPX4 was shown to play a significant role in gamete interactions.

  8. Rat Gpx4 is a moonlighting protein that functions both as a peroxidase, as well as a structural protein.

  9. GPx4-overexpressing mice showed no free fatty acid induced increase in reactive oxygen species and lipid peroxidation

  10. Activity of cutaneous GPx4 is linked to the regulation of COX-2 (show COX2 Antibodies) and hair follicle morphogenesis and provides insight into the function of individual selenoprotein activity in maintaining cutaneous homeostasis.

Cow (Bovine) Glutathione Peroxidase 4 (GPX4) interaction partners

  1. GPx-4 has an important role in the physiological control of peroxide tone in the bordering cells of the oviductal lumen

Glutathione Peroxidase 4 (GPX4) Antigen Profile

Protein Summary

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists\; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

Gene names and symbols associated with GPX4

  • glutathione peroxidase 4a (gpx4a) antibody
  • glutathione peroxidase 4 (GPX4) antibody
  • glutathione peroxidase 4 (Gpx4) antibody
  • 1700027O09Rik antibody
  • cb563 antibody
  • cb691 antibody
  • GP-GPx4 antibody
  • gpx-4 antibody
  • GSHPx-4 antibody
  • MCSP antibody
  • mtPHGPx antibody
  • Phgpx antibody
  • PHGPxa antibody
  • sb:cb563 antibody
  • snGpx antibody
  • snPHGPx antibody
  • wu:fb82e03 antibody
  • zgc:92253 antibody

Protein level used designations for GPX4

glutathione peroxidase 4 , phospholipid hydroperoxidase , phospholipid hydroperoxide glutathione peroxidase, mitochondrial , sperm nucleus glutathione peroxidase , GPx-4 , GSHPx-4 , phospholipid hydroperoxide glutathione peroxidase, nuclear , sperm nuclei glutathione peroxidase , phospholipid hydroperoxide glutathione peroxidase , glutathione peroxidase 4 (phospholipid hydroperoxidase)

GENE ID SPECIES
352928 Danio rerio
2879 Homo sapiens
625249 Mus musculus
29328 Rattus norvegicus
100730119 Cavia porcellus
399537 Sus scrofa
286809 Bos taurus
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