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The protein encoded by GPD1L catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. Additionally we are shipping GPD1L Antibodies (42) and GPD1L Proteins (8) and many more products for this protein.
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In a nonreferred nationwide Danish cohort of SIDS (show IDS ELISA Kits) cases, up to 5/66 (7.5%) of SIDS (show IDS ELISA Kits) cases can be explained by genetic variants in the sodium channel complex genes.
The results of real-time PCR showed that, compared with the paired normal tissues, mRNA levels of GPD1L were decreased significantly in head and neck squamous cell carcinoma.
Common variations in or near CASQ2 (show CASQ2 ELISA Kits), GPD1L, and NOS1AP (show NOS1AP ELISA Kits) are associated with increased risk of sudden cardiac death in patients with coronary artery disease
hypoxia-induced miR (show MLXIP ELISA Kits)-210 represses GPD1L, contributing to suppression of prolyl hydroxylases activity, and increases of HIF-1alpha (show HIF1A ELISA Kits) protein levels.
mutations in GPD1-L as a pathogenic cause for a small subset of sudden infant death syndrome via a secondary loss-of-function mechanism
A GPD1-L mutation decreases SCN5A (show SCN5A ELISA Kits) surface membrane expression, reduces inward Na+ current, and causes Brugada syndrome
No non-synonymous mutations were found, indicating that GPD1L does not appear to be a major cause of Brugada syndrome in a Japanese population.
GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A (show SCN5A ELISA Kits).
Mutations of GPD1-L may downregulate Na(v)1.5 by altering the oxidized to reduced NAD(H) balance.
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).
glycerol-3-phosphate dehydrogenase 1-like protein
, glycerol-3-phosphate dehydrogenase 1-like
, glycerol-3-phosphate dehydrogenase 1-like protein-like