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anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) Antibodies

GGA3 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. Additionally we are shipping GGA3 Proteins (5) and GGA3 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GGA3 260302 Q8BMI3
GGA3 360658  
GGA3 23163 Q9NZ52
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Top anti-GGA3 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GGA3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chimpanzee Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of GGA3 on a Jurkat cell lysate (Human T-cell le... Immunofluorescence staining of human endothelial cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE a... IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xe... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Dog Goat Un-conjugated EIA, IHC (p) Human Kidney (formalin-fixed, paraffin-embedded) stained with GGA3at 2... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Affinity Purified anti-GGA3 antibody shows detectio... 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human Breast (formalin-fixed, paraffin-embedded) stained with GGA3 ant... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC (p), ELISA Human Kidney (formalin-fixed, paraffin-embedded) stained with GGA3 ant... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated IHC, WB WB on rat brain lysate using Rabbit antibody to VHS domain of GGA3 (Go... 100 μL Log in to see 7 to 8 Days
$454.67
Details

GGA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-GGA3 Antibodies

  1. Chimpanzee Polyclonal GGA3 Primary Antibody for EIA, WB - ABIN401317 : Puertollano, Aguilar, Gorshkova, Crouch, Bonifacino: Sorting of mannose 6-phosphate receptors mediated by the GGAs. in Science (New York, N.Y.) 2001 (PubMed)
    Show all 7 references for ABIN401317

  2. Mouse (Murine) Polyclonal GGA3 Primary Antibody for IHC, WB - ABIN350341 : Doray, Bruns, Ghosh, Kornfeld: Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 5 references for ABIN350341

  3. Human Monoclonal GGA3 Primary Antibody for IF, WB - ABIN968814 : Boman, Zhang, Zhu, Kahn: A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi. in Molecular biology of the cell 2000 (PubMed)
    Show all 3 references for ABIN968814

  4. Human Polyclonal GGA3 Primary Antibody for WB - ABIN2786200 : Wang, Sun, Macia, Kirchhausen, Watson, Bonifacino, Yin: PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. in Molecular biology of the cell 2007 (PubMed)

  5. Human Polyclonal GGA3 Primary Antibody for ELISA, WB - ABIN185453 : Prag, Lee, Mattera, Arighi, Beach, Bonifacino, Hurley: Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

More Antibodies against GGA3 Interaction Partners

Mouse (Murine) Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) interaction partners

  1. depletion of GGA1 (show GGA1 Antibodies) and GGA3 engender a rapid and robust elevation of BACE1 (show BACE Antibodies) in the acute phase after brain injury. However, the efficient disposal of the acutely accumulated BACE1 (show BACE Antibodies) solely depends on GGA3 levels in the subacute phase of injury

  2. GGA3 tightly and inversely regulate BACE1 levels via interaction with ubiquitin sorting machinery

Human Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) interaction partners

  1. role of GGA3 in the cell surface export of alpha2B (show ADRA2B Antibodies)-adrenergic receptor

  2. These data indicate that clathrin is required for the function of AP-1 (show FOSB Antibodies)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  3. GGA3 is involved in the cellular processes relevant for Alzheimer's disease pathogenesis.

  4. Subcellular fractionation of Alzheimer's disease cortex with low levels of Golgi-localized GGA proteins shows an alteration of beta-secretase distribution and extensive co-localization with amyloid beta precursor protein APP (show APP Antibodies).

  5. GGA3 tightly and inversely regulate BACE1 levels via interaction with ubiquitin sorting machinery

  6. structures of the VHS domain of human GGA3 complexed with signals from both mannose-6-phosphate receptors

  7. These results indicate that GGA3-S is predominantly expressed in human tissues except the brain and in cell lines.

  8. RNAi of GGA3 expression results in accumulation of the cation-independent mannose 6-phosphate receptor (show IGF2R Antibodies) and internalized epidermal growth factor (EGF (show EGF Antibodies)) within enlarged early endosomes. This perturbation impairs the degradation of internalized EGF (show EGF Antibodies).

  9. found that the human GGA3 protein GAT domain contains two ubiquitin binding motifs that bind to the same surface of ubiquitin

  10. crystal structure of the GAT domain

GGA3 Antigen Profile

Protein Summary

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene.

Gene names and symbols associated with GGA3

  • golgi associated, gamma adaptin ear containing, ARF binding protein 3 (Gga3) antibody
  • golgi-associated, gamma adaptin ear containing, ARF binding protein 3 (GGA3) antibody
  • C230037M19Rik antibody
  • mKIAA0154 antibody

Protein level used designations for GGA3

ADP-ribosylation factor-binding protein GGA3 , golgi-localized, gamma ear-containing, ARF-binding protein 3 , Golgi-localized, gamma ear-containing, ARF-binding protein 3 , golgi associated, gamma adaptin ear containing, ARF binding protein 3 , ADP-ribosylation factor binding protein 3

GENE ID SPECIES
260302 Mus musculus
360658 Rattus norvegicus
23163 Homo sapiens
483310 Canis lupus familiaris
454877 Pan troglodytes
100172741 Pongo abelii
100525777 Sus scrofa
510539 Bos taurus
Selected quality suppliers for anti-GGA3 (GGA3) Antibodies
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