GGA3 Products
(Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010].
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Featured GGA3 Categories
GGA3 Antibodies
High quality antibodies with extensive validation data.
GGA3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GGA3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
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Reactivity
Human
Application
WB, IHC (p), IF, ICC
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- (4)
Cat. No.
ABIN2856386
Quantity
100 μL
Datasheet
Datasheet
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Human
Application
WB, ELISA
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Cat. No.
ABIN129660
Quantity
100 μg
Datasheet
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ABIN7143469
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Datasheet
Recommended GGA3 Proteins
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Cat. No.
ABIN1355041
Quantity
10 μg
Datasheet
Datasheet
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Wheat germ
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Cat. No.
ABIN1355043
Quantity
10 μg
Datasheet
Datasheet
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Tobacco (Nicotiana tabacum)
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ABIN3092757
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Latest Publications for our GGA3 products
: "Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 7, pp. 2334-9, (2005) (PubMed).: "Interactions of GGA3 with the ubiquitin sorting machinery." in: Nature cell biology, Vol. 6, Issue 3, pp. 244-51, (2004) (PubMed).
: "The GAT domains of clathrin-associated GGA proteins have two ubiquitin binding motifs." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54808-16, (2004) (PubMed).
: "Predominant expression of the short form of GGA3 in human cell lines and tissues." in: Biochemical and biophysical research communications, Vol. 306, Issue 3, pp. 687-92, (2003) (PubMed).
: "Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains." in: Nature, Vol. 415, Issue 6874, pp. 933-7, (2002) (PubMed).
: "Sorting of mannose 6-phosphate receptors mediated by the GGAs." in: Science (New York, N.Y.), Vol. 292, Issue 5522, pp. 1712-6, (2001) (PubMed).
: "A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 67-80, (2000) (PubMed).
: "A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi." in: Molecular biology of the cell, Vol. 11, Issue 4, pp. 1241-55, (2000) (PubMed).
: "GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 81-94, (2000) (PubMed).
Synonyms and alternative names related to GGA3
golgi associated, gamma adaptin ear containing, ARF binding protein 3 (Gga3), golgi associated, gamma adaptin ear containing, ARF binding protein 3 (GGA3), C230037M19Rik, mKIAA0154Protein level used designations for GGA3
- ADP-ribosylation factor-binding protein GGA3
- golgi-localized, gamma ear-containing, ARF-binding protein 3
- Golgi-localized, gamma ear-containing, ARF-binding protein 3
- golgi associated, gamma adaptin ear containing, ARF binding protein 3
- ADP-ribosylation factor binding protein 3
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