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Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Additionally we are shipping Goosecoid Homeobox 2 Antibodies (13) and Goosecoid Homeobox 2 Kits (1) and many more products for this protein.
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results indicate that the absence of Gscl and Dgcr14 (show DGCR14 Proteins) in the IP results in altered regulation of REM (show REM1 Proteins) sleep
Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.
homeobox protein goosecoid-2
, goosecoid 2