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anti-Guanidinoacetate N-Methyltransferase (GAMT) Antibodies

The protein encoded by GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Additionally we are shipping GAMT Proteins (15) and GAMT Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAMT 14431 O35969
GAMT 2593 Q14353
GAMT 25257  
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Top anti-GAMT Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GAMT Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-GAMT  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  GAMT is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human hepatocellular carcinoma labeled with Anti-GAMT Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated WB GAMT antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$383.17
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged GAMT is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details

GAMT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,
,
,
Rat (Rattus)


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Top referenced anti-GAMT Antibodies

  1. Human Polyclonal GAMT Primary Antibody for WB - ABIN2775546 : Borini, Staiano, Rocchia, Rossi, Rossi, DAuria: Advanced nanotechnological approaches for designing protein-based "lab-on-chips" sensors on porous silicon wafer. in Recent patents on DNA & gene sequences 2008 (PubMed)
    Show all 2 references for ABIN2775546

  2. Cow (Bovine) Polyclonal GAMT Primary Antibody for WB - ABIN2776937 : Komoto, Huang, Hu, Takata, Konishi, Ogawa, Gomi, Fujioka, Takusagawa: Crystallization and preliminary x-ray diffraction studies of guanidinoacetate methyltransferase from rat liver. in Acta crystallographica. Section D, Biological crystallography 2000 (PubMed)

More Antibodies against GAMT Interaction Partners

Mouse (Murine) Guanidinoacetate N-Methyltransferase (GAMT) interaction partners

  1. Inactivation of the creatine kinase system by GAMT deficiency does not alter mitochondrial organization and intracellular compartmentation in relaxed cardiomyocytes.

  2. GAMT was expressed highly in oligodendrocytes and olfactory ensheathing glia and moderately in astrocytes, whereas GAMT was very low in neurons and microglia.

  3. despite the absence of Cr, GAMT-/- mice can cope with mild ischaemic stress by using phosphorylated guanidinoacetate for high energy phosphoryl transfer

  4. GAMT(Cr)-/- mice showed differences in maximal rates of force rise and relaxation times during the isometric protocol as well as in force during the dynamic protocol.

  5. Our results can provide the basis for additional experiments to optimize Cr supplementation in GAMT deficiency, as increases in brain Cr are slow in patients after Cr supplementation.

  6. GAMT and AGAT (show GATM Antibodies) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (show DMD Antibodies) muscle compared to C57

  7. In the fetal brain, mRNA expression of GAMT was relatively low until 34 days gestation (term is 38-39 days). In the fetal kidney and liver, GAMT mRNA and protein expression were also relatively low until 34-37 days gestation.

Human Guanidinoacetate N-Methyltransferase (GAMT) interaction partners

  1. As early diagnosis results in normal neurodevelopmental outcome, GAMT deficiency should be included in newborn screening programs to diagnose individuals at the asymptomatic stage of the disease

  2. The estimated incidence of GAMT deficiency is 1:250,000 newborns based on our pilot study.

  3. Study reports six novel pathogenic mutations in GAMT gene in patients with Guanidinoacetate methyltransferase deficiency.

  4. Two novel heterozygous variants with sequence deletion and sequence insertion in the GAMT gene have been identified in newborns with guanidinoacetate methyltransferase deficiency.

  5. impact of creatine deficiency syndrome mutations, CRTR (show SLC6A8 Antibodies) and GAMT on metabolic stress was analyzed in patient fibroblast cultures

  6. GAMT genes may not be directly involved in human male infertility

  7. Mutations in the GAMT gene are responsible for GAMT deficiency, since overexpression of the GAMT open reading frame restores GAMT activity in GAMT-deficient fibroblasts.

  8. compound heterozygous mutations in the GAMT gene may be causitive in guanidinoacetate methyltransferase deficiency masquerading as a mitochondrial encephalopathy [case report]

  9. the carrier rate of the c.59G>C; p.Trp20Ser mutation in GAMT is relatively high in these islands, as well as in other parts of Portugal.

  10. Five novel mutations were identified in GAMT from 8 patients with GAMT deficiency.

Zebrafish Guanidinoacetate N-Methyltransferase (GAMT) interaction partners

  1. The spatiotemporal expression pattern of gamt during zebrafish embryogenesis was revealed.

GAMT Antigen Profile

Protein Summary

The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Gene names and symbols associated with GAMT

  • guanidinoacetate N-methyltransferase (gamt) antibody
  • guanidinoacetate N-methyltransferase (GAMT) antibody
  • Guanidinoacetate N-methyltransferase (gamt) antibody
  • guanidinoacetate methyltransferase (Gamt) antibody
  • guanidinoacetate N-methyltransferase (Gamt) antibody
  • AA571402 antibody
  • CCDS2 antibody
  • GAMT antibody
  • GMT antibody
  • MGC75698 antibody
  • PIG2 antibody
  • Spintz1 antibody
  • TP53I2 antibody
  • zgc:123136 antibody

Protein level used designations for GAMT

guanidinoacetate N-methyltransferase , Guanidinoacetate N-methyltransferase , guanidinoacetate methyltransferase

GENE ID SPECIES
394491 Xenopus (Silurana) tropicalis
485085 Canis lupus familiaris
749982 Pan troglodytes
770737 Gallus gallus
100196494 Salmo salar
100528342 Ictalurus punctatus
14431 Mus musculus
2593 Homo sapiens
515270 Bos taurus
25257 Rattus norvegicus
796865 Danio rerio
Selected quality suppliers for anti-GAMT (GAMT) Antibodies
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