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anti-Guanine Nucleotide Binding Protein, alpha Transducing 3 (GNAT3) Antibodies

Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Additionally we are shipping GNAT3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNAT3 346562 A8MTJ3
GNAT3 242851 Q3V3I2
GNAT3 286924 P29348
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Top anti-GNAT3 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB GNAT3 Antibody (Center)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GNAT3 antibody detected the GNAT3 protein (arrow). GNAT3 antibody (Center)  immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the GNAT3 antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of A549 cells using GNAT3 Antibody (Center) Cat.-No AP51877PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma reacted with GNAT3 Antibody (Center) followed  which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated EIA, IHC (p) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Mouse Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA   0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Goat Un-conjugated IHC (p), ELISA 50 μg Log in to see 11 to 13 Days
$541.80
Details

GNAT3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) , , ,
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Rat (Rattus) , , ,
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Top referenced anti-GNAT3 Antibodies

  1. Mouse (Murine) Polyclonal GNAT3 Primary Antibody for IHC, WB - ABIN350355 : He, Yasumatsu, Varadarajan, Yamada, Lem, Ninomiya, Margolskee, Damak: Umami taste responses are mediated by alpha-transducin and alpha-gustducin. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 5 references for ABIN350355

  2. Human Polyclonal GNAT3 Primary Antibody for EIA, FACS - ABIN952565 : Fushan, Simons, Slack, Drayna: Association between common variation in genes encoding sweet taste signaling components and human sucrose perception. in Chemical senses 2010 (PubMed)
    Show all 5 references for ABIN952565

  3. Human Polyclonal GNAT3 Primary Antibody for FACS, IHC (p) - ABIN654441 : Jang, Kokrashvili, Theodorakis, Carlson, Kim, Zhou, Kim, Xu, Chan, Juhaszova, Bernier, Mosinger, Margolskee, Egan: Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 2 references for ABIN654441

More Antibodies against GNAT3 Interaction Partners

Human Guanine Nucleotide Binding Protein, alpha Transducing 3 (GNAT3) interaction partners

  1. (GNAT3, 11 SNPs) gene, located within the 1-LOD support interval region for their association with MS and its related traits. Several SNPs were associated with MS and its related traits. Remarkably.

  2. The sweet taste receptors (alpha-gustducin and T1R3) are involved in glucose-stimulated secretion of GLP-1 and PYY.

  3. the alpha-subunit (show POLG Antibodies) of the taste-specific G protein gustducin is expressed prominently in cells of the human colon

  4. Axonemal-associated localization within the midpiece and principal piece of human spermatozoa raises the possibility that this G protein alpha-subunit (show GNAO1 Antibodies)may process intracellular signals controlling sperm motility.

Mouse (Murine) Guanine Nucleotide Binding Protein, alpha Transducing 3 (GNAT3) interaction partners

  1. T1R3 (show TAS1R3 Antibodies) and alpha-gustducin exhibited a stage-dependent expression pattern during mouse development, and a cell-specific pattern during the spermatogenic cycle.

  2. The role of alpha-gustducin in the development of obesity and adipocyte metabolism

  3. speculate that TAS1R3 (show TAS1R3 Antibodies) and GNAT3 activators may help infertile men, particularly those that are affected by some of the mentioned inhibitors and/or are diagnosed with idiopathic infertility involving signaling pathway of these receptors

  4. Data suggest that alpha-gustducin in colonic mucosa is a key signaling molecule coupling free fatty acid receptors (Gpr43 (show FFAR2 Antibodies), Gpr119 (show GPR119 Antibodies), Gpr120 (show O3FAR1 Antibodies)) and possibly bile acid receptor (show NR1H4 Antibodies) (TGR5 (show GPBAR1 Antibodies)) to secretion of GLP-1 (glucagon-like peptide 1 (show GCG Antibodies)).

  5. This study provides the first evidence that alpha-gustducin is involved in the octanoylation of ghrelin (show GHRL Antibodies).

  6. Data suggest that proteins of the taste transduction cascade (alpha-gustducin, G-protein gamma13, and phospholipase Cbeta2) are expressed in testis (show XKR3 Antibodies) and are in involved in spermatogenesis.

  7. The evidence suggests that alpha-gustducin may selectively participate in signal transduction in the axon terminals of rod bipolar cells in the mammalian retina.

  8. investigated whether T2R-agonists affect (i) ghrelin (show GHRL Antibodies) release via alpha-gustducin and (ii) food intake and gastric emptying via the release of ghrelin (show GHRL Antibodies)

  9. (alpha)--gustducin may be involved in the gurmarin-sensitive sweet reception pathway and may be a key molecule for links between sweet taste receptors and cell type-specific-innervation by their matched fiber class.

  10. alpha-transducin (show GNAT1 Antibodies) has a role in taste receptor cells and taste cell responses that is different from alpha-gustducin

Pig (Porcine) Guanine Nucleotide Binding Protein, alpha Transducing 3 (GNAT3) interaction partners

  1. This study showed an upregulation of selected subpopulations of GNAT3 / alpha-transducin (show GNAT1 Antibodies)-immunoreactive cells in distinct regions of the pig gastrointestinal tract by short- and long-term high protein diet.

  2. The expression of alpha-transducin (show GNAT1 Antibodies) in endocrine and non-endocrine cells located along the length of the porcine gastrointestinal tract is reported.[alpha-transducin (show GNAT1 Antibodies)]

Cow (Bovine) Guanine Nucleotide Binding Protein, alpha Transducing 3 (GNAT3) interaction partners

  1. Axonemal-associated localization within the midpiece and principal piece of bovine spermatozoa raises the possibility that this G protein alpha-subunit (show GNAO1 Antibodies) may process intracellular signals controlling sperm motility

GNAT3 Antigen Profile

Protein Summary

Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase\; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody. Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium. GNAT3 can functionally couple to taste TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors. Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide- 1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP. Thus, may modulate the gut capacity to absorb sugars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.

Gene names and symbols associated with GNAT3

  • guanine nucleotide binding protein, alpha transducing 3 (GNAT3) antibody
  • guanine nucleotide binding protein, alpha transducing 3 (Gnat3) antibody
  • GDCA antibody
  • Ggust antibody
  • gnat-3 antibody
  • Gtn antibody

Protein level used designations for GNAT3

guanine nucleotide-binding protein G(t) subunit alpha-3 , gustducin , guanine nucleotide binding protein, alpha transducing 3 , guanine nucleotide-binding protein G(t) subunit alpha-3-like , gustducin alpha-3 chain , alpha-gustducin

GENE ID SPECIES
427851 Gallus gallus
472426 Pan troglodytes
100012963 Monodelphis domestica
100387752 Callithrix jacchus
100431387 Pongo abelii
100600721 Nomascus leucogenys
346562 Homo sapiens
491406 Canis lupus familiaris
242851 Mus musculus
286924 Rattus norvegicus
100511528 Sus scrofa
516262 Bos taurus
Selected quality suppliers for anti-GNAT3 (GNAT3) Antibodies
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