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alpha subunit of an heterotrimeric G-protein; may function in taste signal transduction. Additionally we are shipping and many more products for this protein.
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Human Polyclonal GNA15 Primary Antibody for IHC, IHC (p) - ABIN4312943
Zanini, Giovinazzo, Alaimo, Lawrence, Pfragner, Bassi, Modlin, Kidd: GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses. in Cellular signalling 2015
GNA15 was not expressed in normal neuroendocrine cells but was overexpressed in gastroenteropancreatic neuroendocrine neoplasia cell lines.
Data indicate the importance of Galpha16 as a downstream effector of the non-canonical Wnt (show WNT2 Antibodies) signaling pathway and as a potential therapeutic target for the treatment of non small cell lung cancer.
G15 (show RBM5 Antibodies) ectopic presence could functionally contribute to the transformation process since siRNA-induced depletion of Galpha15 in pancreatic carcinoma cell lines dramatically inhibited anchorage-independent growth and resistance to the lack of nutrients.
The paper describes G alpha 15 resistance to arrestin (show SAG Antibodies)-desensitization making it differ from other heterotrimeric G proteins (Gq, Gs, Gi, G12 (show TCF3 Antibodies)/13 class)
This paper shows how G alpha 15 and other Gq class members phosphorylate PKD (show PRKD1 Antibodies) in differing patterns
This review summarizes the specific features that distinguish Galpha15/GNA15 (G15 (show RBM5 Antibodies) alpha subunit (show POLG Antibodies)) from all other alpha subunits of the Gq class. G15 (show RBM5 Antibodies) is a heterotrimeric G protein complex that is named after its alpha subunit (show POLG Antibodies).
beta3 region of Galpha16 is essential for interaction with TPR1 and the subsequent activation of Ras
Megakaryocytopoiesis was accompanied by down-regulation of the 43 kDa and 46 kDa variants of G16alpha, constant expression of Gsalpha, and up-regulation of Gqalpha and Gialpha1 (show GNAI1 Antibodies)/2.
role of intracellular loops of cannabinoid CB1 (show CNR1 Antibodies) receptor in functional interaction with Galpha16.
G protein-coupled receptors activate STAT3 (show STAT3 Antibodies) via G alpha(16), a G alpha subunit (show POLG Antibodies) which is primarily expressed in hematopoietic cells.
Data indicate that the hydrophobic core buried between helix 8 and TM1 (show TPM2 Antibodies)-2 of olfactory receptor (mOR (show OPRM1 Antibodies)-S6) is important for the activation of both G protein alpha 15 (Galpha15).
The N-terminal hydrophobic core between helix 8 and TM1 (show TPM2 Antibodies)-2 of mOR (show OPRM1 Antibodies)-S6 is important for activation of both Galpha15_olf and Galpha15.
Gna15 maps to mouse chromosome 10 and has similar tissue distribution to mouse s1p (show S1PR1 Antibodies)(4); transcription of the two genes may be under control of the same enhancer elements
alpha subunit of an heterotrimeric G-protein; may function in taste signal transduction
G-protein subunit alpha-15
, G-protein subunit alpha-16
, epididymis tissue protein Li 17E
, g alpha-15
, g alpha-16
, guanine nucleotide-binding protein subunit alpha-15
, guanine nucleotide-binding protein subunit alpha-16