anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) Antibodies

may play a role in D5 dopamine receptor signal transduction and renal sodium transport. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNA12 2768 Q03113
GNA12 81663 Q63210
GNA12 14673 P27600
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Top anti-GNA12 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Rabbit Anti-GNA12 Antibody Catalog Number: ARP54813_P050 Formalin Fixed Paraffin Embedded Tissue: Human Ovary Tissue Observed Staining: Plasma membrane Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-GNA12 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-GNA12 Antibody (S67) (ABIN392591) in A2058 cell line lysates (35 µg/lane). GNA12(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti GNA12/G protein alpha 12 Polyclonal Antibody, Unconjugated (ABIN753958) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot: G protein alpha 12 Antibody [NBP2-16556] - Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 10% SDS PAGE gel, diluted at 1:2000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

GNA12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GNA12 Antibodies

  1. Human Polyclonal GNA12 Primary Antibody for EIA, WB - ABIN360476 : Suzuki, Nakamura, Mano, Kozasa: Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 5 references for 360476

  2. Cow (Bovine) Polyclonal GNA12 Primary Antibody for WB - ABIN2785900 : Jeske, So, Kelemen, Sukor, Willys, Bulmer, Gordon, Duffy, Stowasser: Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II. in Clinical and experimental pharmacology & physiology 2008 (PubMed)

More Antibodies against GNA12 Interaction Partners

Human Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) interaction partners

  1. the current studies provide evidence showing that c-Jun (show JUN Antibodies) directly binds to a consensus binding sequence within the GNA12-5' regulatory region, thereby regulating GNA12 transcription.

  2. we conclude that Galpha12 protects HUVECs[ human umbilical vein endothelial cells ] from serum withdrawal-induced apoptosis by retaining miR (show MLXIP Antibodies)-155 expression.

  3. RGS22 (show RGS22 Antibodies) acts as a tumor suppressor, repressing human pancreatic adenocarcinoma cell migration by coupling to GNA12/13.

  4. preeclampsia is associated with decreased methylation of the GNA12 promoter

  5. Data show that N-linked glycosylation of protease-activated receptor-1 (PAR1 (show F2R Antibodies)) at extracellular loop 2 (ECL2) controls G12 (show TCF3 Antibodies)/13 versus Gq G-proteins coupling specificity in response to thrombin (show F2 Antibodies) stimulation.

  6. Significance of Galpha12 upregulation in liver tumor progression, implicating Galpha12 as an attractive therapeutic target.

  7. Results show that RMP (show ABCA4 Antibodies) serves as a potent factor contributing to portal vein tumor thrombus by promoting IL-6 (show IL6 Antibodies) transcription.

  8. A tyrosine residue at the C-terminus of the Galpha subunit plays an important role in controlling activation of G-protein coupled receptors.

  9. Galpha12gep oncogene (show RAB1A Antibodies) inhibits FOXO1 (show FOXO1 Antibodies), which may result from the inhibition of FOXO1 (show FOXO1 Antibodies) de novo synthesis by miR (show MLXIP Antibodies)-135b in conjunction with MDM2 (show MDM2 Antibodies)-mediated destabilization of FOXO1 (show FOXO1 Antibodies).

  10. CREB (show CREB1 Antibodies) is a critical signaling node in Lysophosphatidic acid-Lysophosphatidic acid receptor and Galpha12/gep proto-oncogene (show RAB1A Antibodies) stimulated oncogenic signaling in ovarian cancer cells.

Zebrafish Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) interaction partners

  1. Gpr56 (show GPR56 Antibodies) regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA (show RHOA Antibodies)

  2. Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) interaction partners

  1. Galpha12 is required for the development of kidney cysts induced by Pkd1 (show PKD1 Antibodies) mutation in mouse autosomal dominant polycystic kidney disease.

  2. Our data reveal a previously unknown role for Galpha12 in regulating efferocytosis and that renal tubular epithelial cells require KIM-1 (show HAVCR1 Antibodies) to mediate this process.

  3. Selective inhibition of G12 (show TCF3 Antibodies)/13 signaling in macrophages can augment atheroprotective B-cell populations and ameliorate atherosclerosis.

  4. Gpr56 (show GPR56 Antibodies) regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA (show RHOA Antibodies)

  5. results suggest that KIM-1 (show HAVCR1 Antibodies) is an endogenous protective mechanism against renal ischemia-reperfusion injury through inhibition of Galpha12.

  6. Pkd1 (show PKD1 Antibodies) mutation or deletion leads to the activation of Galpha12, which promotes the maturation of ADAM10 (show ADAM10 Antibodies) that increases the shedding of E-cadherin (show CDH1 Antibodies) in kidney epithelial cells.

  7. Galpha12 may play an important role in promoting membrane trafficking and exocytosis for basal and thrombin (show F2 Antibodies)-induced vWF (show VWF Antibodies) secretion, in a process involving SNAP, Galpha12/13 and Galphaq (show GNAQ Antibodies)/11

  8. Data indicate that Pyk2 (show PTK2B Antibodies) is a common signaling effector downstream of both G12 (show TCF3 Antibodies)/13 and integrin alphaIIbbeta3 signaling, which contributes to thromboxane generation.

  9. PRR5L (show PRR5L Antibodies) degradation promotes mTORC2 (show CRTC2 Antibodies)-mediated PKC-delta (show PKCd Antibodies) phosphorylation and cell migration downstream of Galpha12 in fibroblasts and pulmonary fibrosis.

  10. Expression analysis reveals that production of 5-HT7 and Galpha12 proteins in the hippocampus undergoes strong regulation with a pronounced transient increase during early postnatal stages.

GNA12 Antigen Profile

Protein Summary

may play a role in D5 dopamine receptor signal transduction and renal sodium transport

Gene names and symbols associated with GNA12

  • guanine nucleotide binding protein (G protein) alpha 12 (GNA12) antibody
  • guanine nucleotide binding protein (G protein) alpha 12 (Gna12) antibody
  • guanine nucleotide binding protein (G protein) alpha 12a (gna12a) antibody
  • guanine nucleotide binding protein, alpha 12 (Gna12) antibody
  • AI414047 antibody
  • AI504261 antibody
  • Galpha12 antibody
  • gep antibody
  • gna12 antibody
  • gna12l antibody
  • NNX3 antibody
  • RMP antibody

Protein level used designations for GNA12

G-protein subunit alpha-12 , WUGSC:H_GS165O14.2 , g alpha-12 , guanine nucleotide-binding protein subunit alpha-12 , guanine nucleotide binding protein, alpha 12 , Galpha 12 , guanine nucleotide binding protein (G protein) alpha 12

GENE ID SPECIES
2768 Homo sapiens
81663 Rattus norvegicus
769924 Gallus gallus
515159 Bos taurus
503589 Danio rerio
14673 Mus musculus
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