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anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) Antibodies

The protein encoded by GNL3L appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Additionally we are shipping GNL3L Proteins (4) and GNL3L Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNL3L 54552 Q9NVN8
GNL3L 237107 Q6PGG6
GNL3L 100034253  
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Top anti-GNL3L Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB WB Suggested Anti-GNL3L Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Lung WB Suggested Anti-GNL3L  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-GNL3L Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Lung WB Suggested Anti-GNL3L  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, WB GNL3L Antibody (N-term) (ABIN654998) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the GNL3L antibody detected the GNL3L protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of MDA-MB231 cells using GNL3L Antibody (N-term) Cat.-No AP51883PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of GNL3L Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the GNL3L antibody detected the GNL3L protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293/HeLa/HT-29 cells, using GNL3L Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of GNL3L staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GNL3L expression in Lovo (A), HeLa (B), NIH3T3 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit APC FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

GNL3L Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GNL3L Antibodies

  1. Human Polyclonal GNL3L Primary Antibody for EIA, FACS - ABIN952568 : Rao, Kumari, Balasundaram, Sankaranarayanan, Mahalingam: A novel lysine-rich domain and GTP binding motifs regulate the nucleolar retention of human guanine nucleotide binding protein, GNL3L. in Journal of molecular biology 2006 (PubMed)
    Show all 2 references for ABIN952568

  2. Human Polyclonal GNL3L Primary Antibody for ELISA, WB - ABIN1534972 : Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005 (PubMed)

  3. Human Polyclonal GNL3L Primary Antibody for FACS, WB - ABIN654998 : Du, Rao, Chen, Wu, Mahalingam, Balasundaram: The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA. in Molecular biology of the cell 2005 (PubMed)

More Antibodies against GNL3L Interaction Partners

Human Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) interaction partners

  1. the present study provides evidence that GNL3L is exported from the nucleus in CRM1 (show XPO1 Antibodies) dependent manner and the nuclear localization of GNL3L is important to promote 'S' phase progression during cell proliferation.

  2. GNL3L depletion impairs ribosome production without inducing appreciable DNA damage. During evolution, GNL3L retained the role of the ancestral gene in ribosome biosynthesis, whereas the paralogous nucleostemin (show E2IG3 Antibodies) acquired a novel genome-protective function.

  3. differences in the relative nucleostemin (show E2IG3 Antibodies) protein and mRNA levels may reflect the degree of proliferation of mesnchymal stem cells and can be used to characterize in vitro expansion capabilities

  4. GNL3L bound MDM2 (show MDM2 Antibodies) in vivo, stabilizing MDM2 (show MDM2 Antibodies) and preventing its ubiquitylation. GNL3L depletion upregulated specific p53 (show TP53 Antibodies) targets (Bax (show BAX Antibodies), 14-3-3sigma and p21 (show CDKN1A Antibodies)).

  5. analysis uncovers an important role for Grn1p/GNL3L within this unique group of nucleolar GTPases

  6. GNL3L is composed of distinct modules, each of which plays a specific role in molecular interactions for its nucleolar retention and subsequent function(s) within the nucleolus

Mouse (Murine) Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) interaction partners

  1. work reveals a novel mechanism that negatively regulates the transcriptional function of ERRgamma (estrogen-related receptor (show ESRRG Antibodies))by GNL3L through coactivator competition.

  2. GNL3L mediates the mitotic increase of TRF1 (show TERF1 Antibodies) protein and promotes the metaphase-to-anaphase transition.

GNL3L Antigen Profile

Protein Summary

The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with GNL3L

  • guanine nucleotide binding protein-like 3 (nucleolar)-like (gnl3l) antibody
  • guanine nucleotide binding protein-like 3 (nucleolar)-like (GNL3L) antibody
  • guanine nucleotide binding protein-like 3 (nucleolar)-like (Gnl3l) antibody
  • BC020354 antibody
  • flj10613 antibody
  • flj10613l antibody
  • si:dkey-13a21.8 antibody
  • SI:zK13A21.8 antibody
  • zgc:110536 antibody

Protein level used designations for GNL3L

guanine nucleotide-binding protein-like 3-like protein , guanine nucleotide binding protein-like 3 (nucleolar)-like , guanine nucleotide-binding protein-like 3-like protein-like , novel GTPase

GENE ID SPECIES
442932 Danio rerio
496093 Xenopus laevis
100465620 Ailuropoda melanoleuca
100603832 Nomascus leucogenys
54552 Homo sapiens
507679 Bos taurus
237107 Mus musculus
100034253 Rattus norvegicus
480933 Canis lupus familiaris
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