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anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) Antibodies

The protein encoded by E2IG3 may interact with p53 and may be involved in tumorigenesis. Additionally we are shipping Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Proteins (6) and Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
E2IG3 26354 Q9BVP2
E2IG3 30877 Q8CI11
E2IG3 290556 Q811S9
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Top anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Antibodies at antibodies-online.com

Showing 10 out of 117 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GNL3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-GNL3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  GNL3 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GNL3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of GNL3 Antibody (C-term) (ABIN388154) in HL60 cell line lysates (35 µg/lane). GNL3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GNL3 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC, WB Detection of Human and Mouse GNL3 by Western Blot (H & M) and Immunoprecipitatation (H). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse 3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-GNL3 antibody ABIN151112 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B). GNL3 was also immunoprecipitated using rabbit anti-GNL3 antibodies ABIN151113 and another GNL3 Ab. Detection: Chemiluminescence with exposure times of 10 seconds (A and B). Immunohistochemistry-Paraffin: Nucleostemin Antibody [ABIN151112] - Human skin carcinoma. Antibody used at a dilution of 1:200. 0.1 mL Log in to see 5 to 7 Days
$486.94
Details
Human Goat Un-conjugated ELISA, WB Western Blot: Nucleostemin Antibody [NBP2-42528] - Analysis of HeLa (A )HepG2 (B) and K562 (C) nuclear lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 3 to 4 Days
$430.10
Details
Mouse Rabbit Un-conjugated WB Mouse Gnl3 Antibody (C-term) (ABIN1881380) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the Mouse Gnl3 antibody detected the Mouse Gnl3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

E2IG3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Antibodies

  1. Mouse (Murine) Polyclonal E2IG3 Primary Antibody for WB - ABIN1881380 : Hirai, Romanova, Kellner, Verma, Rayner, Asakura, Kikyo: Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for ABIN1881380

  2. Human Polyclonal E2IG3 Primary Antibody for IHC (p), IP - ABIN151112 : Okamoto, Yasukawa, Nguyen, Kasim, Maida, Possemato, Shibata, Ligon, Fukami, Hahn, Masutomi: Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)
    Show all 2 references for ABIN151112

  3. Human Polyclonal E2IG3 Primary Antibody for ELISA, WB - ABIN4341079 : Yoshida, Fujimoto, Kudoh, Nagata, Nakayama, Shinohara, Ito: Nucleostemin affects the proliferation but not differentiation of oral squamous cell carcinoma cells. in Cancer science 2011 (PubMed)

  4. Human Monoclonal E2IG3 Primary Antibody for ELISA, WB - ABIN1724769 : Meng, Hsu, Tsai: GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest. in Oncogene 2011 (PubMed)

  5. Human Polyclonal E2IG3 Primary Antibody for EIA, IHC (p) - ABIN356871 : Ma, Pederson: Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway. in Molecular biology of the cell 2007 (PubMed)

More Antibodies against Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Interaction Partners

Zebrafish Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. The nucleolar GTP-binding (show RND2 Antibodies) proteins Gnl2 (show GNL2 Antibodies) and nucleostemin are required for retinal neurogenesis in developing zebrafish.

Human Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Identified a positive correlation between up-regulation of nucleostemin and human glioma cell proliferation and that knocking-down nucleostemin alleviated glioma proliferation by reducing beta-Catenin (show CTNNB1 Antibodies) transportation into the nucleus.

  2. Relative expression of GNL3 in synovial tissue and fluid samples was significantly higher in the osteoarthritic group as compared to the non-osteoarthritic group.

  3. The expression level of GNL3 was examined in 89 human gastric cancer samples using immunohistochemistry (IHC) staining. GNL3 in gastric cancer tissues was significantly upregulated compared with paracancerous tissues.

  4. over-expression of GNL3 and SKA3 (show SKA3 Antibodies) in the PC-3 (show PCSK1 Antibodies) human prostate cancer cell line decreased in vitro cell migration and invasion

  5. p53 (show TP53 Antibodies) activation by inauhzin via inhibiting SIRT1 (show SIRT1 Antibodies), also inhibits cellular IMPDH2 (show IMPDH2 Antibodies) activity, reduces the levels of cellular GTP (show AK3 Antibodies) and GTP-binding (show RND2 Antibodies) nucleostemin, thus representing in a new anti-cancer strategy.

  6. overexpression of NS suppressed ARF (show CDKN2A Antibodies) polyubiquitination by its E3 ligase Ubiquitin Ligase for ARF (show CDKN2A Antibodies) and elongated its half-life, whereas knockdown of NS led to the decrease of ARF (show CDKN2A Antibodies) levels

  7. Silence of nucleostemin inhibit cell proliferation through up-regulating p21 (show CDKN1A Antibodies) expression and nucleostemin may be involved in the pathogenesis of esophageal squamous cell carcinoma.

  8. It is concluded that nucleostemin expression could not be specific in a certain type of cells in colon cancer cell line HT29.

  9. Data shows that the NS protein expression status was positively correlated with both ER and HER2 (show ERBB2 Antibodies) status and was a powerful prognostic factor.

  10. cis (show CISH Antibodies)-acting regulatory polymorphisms acting on GNL3 and SPCS1 (show SPCS1 Antibodies) contribute to the OA association signal at chromosome 3p21, and these genes therefore merit further investigation.

Mouse (Murine) Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Nucleostemin expression participates in the preservation of the viability and integrity of embryonic stem cells.

  2. nucleostemin protects hematopoietic stem cells (HSCs) from DNA damage accumulation and is required for the maintenance of HSCs.

  3. Mechanistic studies performed in mouse embryonic fibroblast cells showed that loss of nucleostemin triggers DNA damage and growth arrest independently of the p53 (show TP53 Antibodies) status or rRNA synthesis

  4. Nucleostemin in the maintenance of ESC self-renewal, demonstrate the importance of rapid transit through G1 for this process, and expand the known classes of reprogramming factors.

  5. NS functions downstream of Myc (show MYC Antibodies) as a rate-limiting regulator of cell proliferation and transformation.

  6. NS undergoes a ubiquitin- and MDM2 (show MDM2 Antibodies)-independent proteasomal degradation when intracellular GTP (show AK3 Antibodies) levels are markedly reduced

  7. a complex composed of TERT (show TERT Antibodies), BRG1 (show SMARCA4 Antibodies), and NS/GNL3L (show GNL3L Antibodies) maintains the function of tumor initiating cells

  8. Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.

  9. analysis of nucleolar localization of stem cell protein (show TAL1 Antibodies) nucleostemin

  10. Nucleostemin has a unique ability, derived from an ancestral function, to control the proliferation rate of stem/progenitor cells in vivo independently of p53.

Xenopus laevis Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Nucleostemin functions in early amphibian development to control cell proliferation of neural progenitor cells.

Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) Antigen Profile

Protein Summary

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with E2IG3

  • guanine nucleotide binding protein-like 3 (nucleolar) (gnl3) antibody
  • guanine nucleotide binding protein-like 3 (nucleolar) (GNL3) antibody
  • guanine nucleotide binding protein-like 3 (nucleolar) (LOC100231668) antibody
  • guanine nucleotide binding protein-like 3 (nucleolar) (Gnl3) antibody
  • BC037996 antibody
  • C77032 antibody
  • E2IG3 antibody
  • id:ibd2914 antibody
  • NNP47 antibody
  • Ns antibody
  • nstm antibody
  • wu:fb38a04 antibody
  • wu:fc55d07 antibody
  • zgc:123093 antibody

Protein level used designations for E2IG3

guanine nucleotide-binding protein-like 3 , nucleostemin , nucleostemin-like protein , guanine nucleotide binding protein-like 3 (nucleolar) , guanine nucleotide-binding protein-like 3-like , E2-induced gene 3 protein , estradiol-induced nucleotide binding protein , novel nucleolar protein 47 , nucleolar GTP-binding protein 3

GENE ID SPECIES
321897 Danio rerio
394765 Xenopus (Silurana) tropicalis
415897 Gallus gallus
100155235 Sus scrofa
100231668 Taeniopygia guttata
100458988 Pongo abelii
26354 Homo sapiens
30877 Mus musculus
100685258 Canis lupus familiaris
506152 Bos taurus
290556 Rattus norvegicus
380340 Xenopus laevis
Selected quality suppliers for anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) Antibodies
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