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anti-Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) Antibodies

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. Additionally we are shipping GUCY1A3 Proteins (6) and GUCY1A3 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GUCY1A3 2982 Q02108
GUCY1A3 60596 Q9ERL9
GUCY1A3 497757  
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Top anti-GUCY1A3 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (LEFT)Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab (1:40 dilution). (RIGHT)Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry analysis of GCS-alpha-1 antibody in paraffin-embedded human lung carcinoma tissue. Western blot analysis of GCS-alpha-1 antibody in extracts from THP1 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of GUCY1A3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GUCY1A3 expression in THP1 (A), KNRK (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC (p), ELISA, WB   100 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB 250 μL Log in to see 11 to 13 Days
$541.80
Details

GUCY1A3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-GUCY1A3 Antibodies

  1. Human Polyclonal GUCY1A3 Primary Antibody for EIA, IHC (p) - ABIN359277 : Saino, Maruyama, Sekiya, Kayama, Murakami: Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3. in Oncology reports 2004 (PubMed)
    Show all 4 references for ABIN359277

  2. Human Polyclonal GUCY1A3 Primary Antibody for EIA, WB - ABIN493440 : Wedel, Garbers: Guanylyl cyclases: approaching year thirty. in Trends in endocrinology and metabolism: TEM 2008 (PubMed)
    Show all 3 references for ABIN493440

  3. Human Monoclonal GUCY1A3 Primary Antibody for ICC, FACS - ABIN1724788 : Zhong, Pan, Liu, Wang, Ying, Su, Huang, Tan: A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase. in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2011 (PubMed)
    Show all 2 references for ABIN1724788

More Antibodies against GUCY1A3 Interaction Partners

Human Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) interaction partners

  1. Expression of the alpha1-A680T sGC (show SGCB Antibodies) variant in reporter cells resulted in higher cyclic guanosine monophosphate production compared with the wild-type enzyme and the purified alpha1-A680T sGC (show SGCB Antibodies) exhibited enhanced sensitivity to nitric oxide in vitro.

  2. Dynamic interplay between hsp90 (show HSP90 Antibodies), apo (show C9orf3 Antibodies)-sGC (show SGCB Antibodies)-beta1, and sGC (show SGCB Antibodies)-alpha1 in response to NO is unprecedented and represent new steps by which cells can modulate the heme content and activity of sGC (show SGCB Antibodies) for signaling cascades.

  3. ZNF280B (show ZNF280B Antibodies) upregulates GUCY1A3 expression and downregulates TP53 (show TP53 Antibodies) in prostate cancer cells.

  4. homozygous mutations in GUCY1A3, which encodes the alpha1 subunit of soluble guanylate cyclase, the major receptor for nitric oxide, might play a role in moyamoya and achalasia

  5. The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase

  6. GCS-alpha-1 regulation of p53 (show TP53 Antibodies) activity is important in prostate cancer biology and may represent an important mechanism of p53 (show TP53 Antibodies) down-regulation.

  7. We concluded that the alpha-subunit (show POLG Antibodies) and the beta(1)(191-619) domain exert structural strains on the heme domain.

  8. analysis of pharmacological response to direct sGC (show SGCB Antibodies) activators in coronary artery disease patients

  9. A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase

  10. C-alpha1 sGC (show SGCB Antibodies) splice form is expressed at high levels in differentiating cells and its intracellular distribution varies from canonical alpha1 sGC (show SGCB Antibodies) subunit.

Mouse (Murine) Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) interaction partners

  1. The authors elucidated this dependency by showing that guanylate cyclase-1 is a novel rhodopsin (show RHO Antibodies)-binding protein.

  2. Cellular markers revealed that vascular SMC (show DYM Antibodies) differentiation decreased, whereas myofibroblast activation increased in the hyperoxic sGC (show NPR1 Antibodies)-alpha1 KO pup lung.

  3. Soluble guanylate cyclase alpha1-deficient mice: a novel murine model for primary open angle glaucoma.

  4. Male mice deficient in a NO receptor component, the alpha1 subunit of soluble guanylate cyclase (sGCalpha1), are prone to hypertension in some, but not all, mouse strains, suggesting that additional genetic factors contribute to the onset of hypertension

  5. These data suggests a novel physiological role for PDE5 (show PDE5A Antibodies) in restricting the effects of NOS3 (show NOS3 Antibodies)/sGC (show NPR1 Antibodies)/PKG (show PRKG1 Antibodies) signaling pathway to modulating beta-AR stimulated I(Ca), while limiting effects on cardiac contraction.[sGC (show NPR1 Antibodies)]

  6. Pressure overload results in translocation of sGC (show NPR1 Antibodies) out of membrane microdomains, depressing NO/heme-dependent activation in the heart, consistent with enhanced oxidation.

  7. findings identify a crucial role of the NO/sGCalpha1beta1/cGMP pathway in modulating lymphatic vessel function [soluble guanylate cyclase alpha1beta1]

  8. RD3 (show RD3 Antibodies) mediates the export of GC1 from the endoplasmic reticulum to endosomal vesicles, and that the C terminus of GC1 is required for RD3 (show RD3 Antibodies) binding

  9. TGF-beta(1 (show TGFB1 Antibodies)) decreased sGC (show NPR1 Antibodies) and PKGI (show PRKG1 Antibodies) expression in pulmonary artery and aortic smooth muscle cells from adult rats and mice.

  10. Requirement of both alpha-2 and alpha-1 guanylate cyclases for signaling in long-term potentiation (LTP (show SCP2 Antibodies)) indicates the existence of two distinct nitric oxide/cGMP-mediated pathways, which have to work in concert for expression of LTP (show SCP2 Antibodies).

Cow (Bovine) Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) interaction partners

  1. We concluded that the alpha-subunit (show POLG Antibodies) and the beta(1)(191-619) domain exert structural strains on the heme domain.

  2. The N-terminal region of nitric oxide-sensitive guanylyl cyclase alpha 1 subunit(amino acids 61-128) is mandatory for quantitative dimerization.

GUCY1A3 Antigen Profile

Protein Summary

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene names and symbols associated with GUCY1A3

  • guanylate cyclase 1, soluble, alpha 3 (GUCY1A3) antibody
  • guanylate cyclase 1, soluble, alpha 3 (gucy1a3) antibody
  • si:dkey-264b2.3 (si:dkey-264b2.3) antibody
  • guanylate cyclase 1, soluble, alpha 3 (LOC100223563) antibody
  • soluble guanylyl cyclase alpha subunit (gucy1a3) antibody
  • guanylate cyclase 1, soluble, alpha 3 (Gucy1a3) antibody
  • 1200016O07Rik antibody
  • GC-SA3 antibody
  • GUC1A3 antibody
  • GUCA3 antibody
  • GUCSA3 antibody
  • Gucy1a1 antibody
  • gucy1a3 antibody
  • im:7136149 antibody
  • SGC antibody
  • sgc1a1 antibody
  • zgc:112159 antibody

Protein level used designations for GUCY1A3

guanylate cyclase 1, soluble, alpha 3 , guanylate cyclase soluble subunit alpha-3 , soluble guanylate cyclase large subunit alpha 1 , soluble guanylate cyclase 1 alpha 3 , si:dkey-264b2.3 , guanylate cyclase soluble subunit alpha-3-like , soluble guanylyl cyclase alpha subunit , GC-S-alpha-1 , GCS-alpha-1 , GCS-alpha-3 , soluble guanylate cyclase large subunit , alpha 1 sGC , Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase) , Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase) , NO-sensitive GC alpha 1 subunit , guanylate cyclase soluble subunit alpha-1 , larger subunit of soluble guanylyl cyclase , nitric oxide-sensitive guanylyl cyclase alpha 1 subunit

GENE ID SPECIES
422407 Gallus gallus
550420 Danio rerio
553100 Sus scrofa
699365 Macaca mulatta
100017038 Monodelphis domestica
100069573 Equus caballus
100150025 Danio rerio
100172608 Pongo abelii
100223563 Taeniopygia guttata
100294641 Ovis aries
100396127 Callithrix jacchus
100547213 Meleagris gallopavo
100581660 Nomascus leucogenys
100608597 Pan troglodytes
100049177 Oryzias latipes
2982 Homo sapiens
60596 Mus musculus
497757 Rattus norvegicus
482663 Canis lupus familiaris
281216 Bos taurus
Selected quality suppliers for anti-GUCY1A3 (GUCY1A3) Antibodies
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