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H2.0-Like Homeobox Proteins (HLX)

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Additionally we are shipping HLX Antibodies (53) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLX 3142 Q14774
HLX 15284 Q61670
HLX 364069 A0JPN1
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Top HLX Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,344.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,375.17
Details

HLX Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for H2.0-Like Homeobox (HLX) Interaction Partners

Zebrafish H2.0-Like Homeobox (HLX) interaction partners

  1. Hlx1 selectively marks sprouting endothelial cells during zebrafish development.Hlx1 is required for intersegmental vessel angiogenesis in zebrafish embryos.Hlx1 cell-autonomously maintains endothelial stalk cell potential.

Human H2.0-Like Homeobox (HLX) interaction partners

  1. Studies have identified HLX as a novel key transcription factor involved in the regulation of early hematopoiesis and AML (show RUNX1 Proteins) pathogenesis.

  2. The expression levels of Hlx, T-bet, and IFN-gamma (show IFNG Proteins) were significantly decreased.

  3. Data suggest that HLX1 is downstream mediator of hepatocyte growth factor- (HGF (show HGF Proteins)-) induced cell survival, cell proliferation, and invasive properties of trophoblast cells; thus, both HGF (show HGF Proteins) and HLX1 appear to be involved in normal placental development.

  4. This study identifies HLX as a key regulator in immature hematopoietic and leukemia cells and as a prognostic marker and therapeutic target in acute myeloid leukemia (show BCL11A Proteins).

  5. This study investigated the influence of TBX21 and HLX1 single nucleotide polymorphisms (SNPs), which have previously been shown to be associated with asthma, on T(H)1/T(H)2 lineage cytokines at birth.

  6. a functional polymorphism in HLX in combination with the TBX21 polymorphism is also associated with the prognosis of Graves' disease.

  7. These data suggest that HLX may function to balance attractive with repulsive vessel guidance by up-regulating UNC5B (show UNC5B Proteins) and to down-modulate sprouting under normoxic conditions.

  8. HLX is a mediator of HGF/c-met-dependent trophoblast migration but is not involved in the regulation of trophoblast invsion.

  9. Cell cycle regulatory genes RB1 (show RB1 Proteins), MYC (show MYC Proteins), CCNB1 (show CCNB1 Proteins), ELK1 (show ELK1 Proteins), JUN (show JUN Proteins), and CDKN1C (show CDKN1C Proteins), which control important trophoblast cell functions, are targets of HLX.

  10. Decreased HLX1 expression is associated with idiopathic fetal growth restriction

Mouse (Murine) H2.0-Like Homeobox (HLX) interaction partners

  1. methyl-CpG-binding domain protein 2 (MBD2), an epigenetic regulator, controls autoimmunity and EAE through T-bet/Hlx.

  2. Hlx regulates sprouting in vitro, but its role in sprouting is nonessential in vivo. HLX is regulated by shear stress and a subtle defect in vascular remodeling is present in knockout embryos.

  3. Results shown that over-expressed Hlx in DC2.4 up-regulated the transcription and expression of IFN-gamma, increased the expression of maturation makers including CD40, CD80, CD86, MHC-I and MHC-II

  4. Transient over-expression of Hlx in DC2.4 promotes DC2.4 maturation and up-regulates IL-12 (show IL12A Proteins), IL-10 (show IL10 Proteins) and TGF-beta (show TGFB1 Proteins) expression. H1x (show H1FX Proteins) modified DC2.4 cells seem to function as regulatory dendritic cells

  5. Hlx expression in activated NK cells temporally controls and limits the monokine-induced production of interferon-gamma (show IFNG Proteins)

HLX Protein Profile

Protein Summary

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).

Gene names and symbols associated with H2.0-Like Homeobox Proteins (HLX)

  • H2.0-like homeobox (BRAFLDRAFT_290377)
  • H2.0-like homeo box 1 (Drosophila) (hlx1)
  • H2.0-like homeobox (HLX)
  • H2.0-like homeobox (Hlx)
  • fa28a07 protein
  • HB24 protein
  • Hlx1 protein
  • wu:fa28a07 protein
  • zgc:76923 protein

Protein level used designations for H2.0-Like Homeobox Proteins (HLX)

H2.0-like homeobox , H2.0-like homeobox protein , H2.0-like homeo box 1 , H2.0-like homeo box-1 , H2.0-like homeobox 1 , homeobox protein HB24 , homeobox protein HLX1

GENE ID SPECIES
7217998 Branchiostoma floridae
327096 Danio rerio
3142 Homo sapiens
519165 Bos taurus
15284 Mus musculus
364069 Rattus norvegicus
Selected quality suppliers for HLX Proteins (HLX)
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