anti-H3 Histone, Family 3A (H3F3A) Antibodies

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Additionally we are shipping Histone H3.3 Proteins (5) and Histone H3.3 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
H3F3A 289314  
H3F3A 3020 P84243
H3F3A 15078 P84244
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Top anti-Histone H3.3 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: Rabbit  Sample Tissue: Human Brain lysates  Antibody Dilution: 1.0 µg/mL Host: Rabbit Target Name: HIST3H3 Sample Type: Human Brain lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-H3f3a Antibody Titration: 1.0 ug/ml Positive Control: Mouse Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, WB Human H3F3A Western blot (WB) 13112 100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB Histone H3.3 antibody flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis. Histone H3.3 antibody IHC analysis in formalin fixed and paraffin embedded testis tissue. 0.4 mL Log in to see 2 to 3 Days
$411.13
Details
Human Rabbit Un-conjugated DB, ELISA Dot blot analysis of phospho-Histone H3.3 antibody. 50ng of Methyl-peptide or Non Methyl-peptide per dot were spotted. 0.4 mL Log in to see 2 to 3 Days
$411.13
Details
Human Rabbit Un-conjugated IHC (p), WB   50 μg Log in to see 12 to 14 Days
$541.80
Details
Human Rabbit Un-conjugated ICC, IF, IHC, WB   100 μL Log in to see 16 Days
$412.50
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 13 to 16 Days
$313.50
Details
Human Rabbit FITC FACS, ICC, IF, IHC   150 μg Log in to see 2 to 3 Days
$385.00
Details

H3F3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)

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Human , , , ,

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Mouse (Murine)

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Top referenced anti-Histone H3.3 Antibodies

  1. Human Polyclonal Histone H3.3 Primary Antibody for WB - ABIN2792109 : Wells, Kedes: Structure of a human histone cDNA: evidence that basally expressed histone genes have intervening sequences and encode polyadenylylated mRNAs. in Proceedings of the National Academy of Sciences of the United States of America 1985 (PubMed)

More Antibodies against Histone H3.3 Interaction Partners

Xenopus laevis H3 Histone, Family 3A (H3F3A) interaction partners

  1. Downregulation of the H3.3 histone chaperone HIRA (show HIRA Antibodies) similarly impairs late gastrulation.

Fruit Fly (Drosophila melanogaster) H3 Histone, Family 3A (H3F3A) interaction partners

  1. FACT and PBAP complexes are recruited to chromatin boundaries in a GAGA factor-dependent manner, and are needed for H3.3 replacement to execute boundary functions.

  2. describe a mechanism of chromatin regulation whereby the variant H3.3 is deposited at particular loci, including active rDNA arrays

  3. Histone H3.3 gene may be required to provide postmeiotic histone H3.3 in the male germ line in transition to chromatin packaging in sperm.

  4. Deposition and inheritance of actively modified H3.3 in regulatory regions maintains transcriptionally active chromatin.

Human H3 Histone, Family 3A (H3F3A) interaction partners

  1. We determined the incidence of H3.3 G34 mutations in primary malignant bone tumors as assessed by genotype and H3.3 G34W immunostaining

  2. The kinase activity of Aurora B (show AURKB Antibodies) on serine 31 of histone H3.3 was biochemically confirmed with nucleosomal substrates in vitro.

  3. This study showed that heterozygous K27M mutations in H3F3A (n = 4) or HIST1H3B (show HIST1H3D Antibodies) (n = 3) across all primary, contiguous, and metastatic tumor sites in all Diffuse intrinsic pontine glioma.

  4. Study examined the relationship of K27M mutations in the distinct histone H3 (show HIST3H3 Antibodies) variants (i.e. HIST1H3B (show HIST1H3D Antibodies) and H3F3A) with specific pontine glioma biology

  5. study found spinal high-grade gliomas in children and adults frequently harbor H3F3A (K27M) mutations

  6. H3F3A and H3F3B mutation analysis appears to be a highly specific, although less sensitive, diagnostic tool for the distinction of GCTB and chondroblastoma from other giant cell-containing tumors.

  7. we describe three interesting cases of paediatric glial and glioneuronal tumours harbouring both BRAF (show BRAF Antibodies) V600E and H3F3A K27M mutations.

  8. our observations further extend the knowledge of H3F3A mutation and its location in pediatric glioblastomas

  9. The CENP-A (show CENPA Antibodies)/histone H3.3 nucleosome forms an unexpectedly stable structure and allows the binding of the essential centromeric protein, CENP-C (show CENPC1 Antibodies), which is ectopically mislocalized in the chromosomes of CENP-A (show CENPA Antibodies) overexpressing tumor cells.

  10. On the basis of our findings, H3F3A p.Gly34 Trp (show TBPL1 Antibodies) or p.Gly34 Leu mutations are not a frequent event in CGCL.

Mouse (Murine) H3 Histone, Family 3A (H3F3A) interaction partners

  1. Data show that circulating histone H3 (show HIST3H3 Antibodies) increased significantly in necrotizing pancreatitis.

  2. In H3f3a and H3f3b null mouse embryonic stem cells, H3.3 deficiency results in reduced levels of H3K9me3 level, H4K20me3 and ATRX (show ATRX Antibodies) at the telomeres, accompanied with an increase in telomeric transcription.

  3. an important function of H3.3 is to support chromosomal heterochromatic structures, thus maintaining genome integrity during mammalian development.

  4. Data indicate a function of the histone H3S28 phosphorylation mark in the activation of mammalian genes in response to MAP kinase (show MAPK1 Antibodies) pathway activation.

  5. Data indicate that increased tumor necrosis factor (Tnfa (show TNF Antibodies)) and monocyte chemotactic protein 1 (Mcp1 (show CCL2 Antibodies); also known as Ccl2 (show CCL2 Antibodies)) expression in fatty liver at the chromatin level corresponds to changes in the level of histone H3 (show HIST3H3 Antibodies) acetylation.

  6. An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation.

  7. Histone H3.3 regulates dynamic chromatin states during spermatogenesis.

  8. H3.3 is a crucial maternal factor (show ZAR1 Antibodies) for oocyte reprogramming

  9. Data demonstrate the importance of H3.3 in maintaining a chromatin landscape in embryonic stem cells that is important for proper gene regulation during differentiation.

  10. H3.3 mediates a balance between open and condensed chromatin that is crucial for the fidelity of chromosome segregation during early mouse development.

Pig (Porcine) H3 Histone, Family 3A (H3F3A) interaction partners

  1. Data suggest the combination of three genes RPL32 (show RPL32 Antibodies), RPS18 (show RPS18 Antibodies), and H3F3A is the most suitable for accurate normalization.

Histone H3.3 (H3F3A) Antigen Profile

Protein Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.

Gene names and symbols associated with H3F3A

  • H3 histone, family 3A (H3f3a) antibody
  • H3 histone, family 3A (h3f3a) antibody
  • H3 histone, family 3B (H3.3B) (H3F3B) antibody
  • H3 histone, family 3B (H3F3B) antibody
  • histone cluster 1, H3a (HIST1H3A) antibody
  • H3 histone, family 3A (LOAG_05159) antibody
  • H3 histone, family 3A (LOC100346558) antibody
  • H3 histone, family 3A (LOC100357927) antibody
  • Histone H3.3A (His3.3A) antibody
  • H3 histone, family 3A (H3F3A) antibody
  • H3 histone, family 3A (H3.3A) antibody
  • CG5825 antibody
  • dH3.3A antibody
  • Dmel\\CG5825 antibody
  • H3.3 antibody
  • H3.3A antibody
  • H3.3B antibody
  • H3F3 antibody
  • H3F3A antibody
  • His-3.3A antibody
  • His3.3 antibody
  • MGC52829 antibody
  • PH3 antibody
  • wu:fb58e10 antibody
  • zgc:56193 antibody
  • zgc:86731 antibody

Protein level used designations for H3F3A

H3 histone, family 3A , H3 histone, family 3B (H3.3B) , CG5825-PA , CG5825-PC , CG5825-PD , H3L-like histone , His3.3A-PA , His3.3A-PC , His3.3A-PD , histone H3.3 , histone H3.3 variant , histone H3.3A , histone variant 3.3 , histone variant H3.3 , fb58e10 , lamprey , lpy

GENE ID SPECIES
289314 Rattus norvegicus
399418 Xenopus laevis
448680 Xenopus (Silurana) tropicalis
475916 Canis lupus familiaris
480110 Canis lupus familiaris
617051 Bos taurus
737454 Pan troglodytes
9942563 Loa loa
100346558 Oryctolagus cuniculus
100357927 Oryctolagus cuniculus
33736 Drosophila melanogaster
3020 Homo sapiens
15078 Mus musculus
396970 Sus scrofa
100328923 Oryctolagus cuniculus
406269 Danio rerio
326601 Bos taurus
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