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Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity). Additionally we are shipping HECTD2 Antibodies (52) and many more products for this protein.
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studies describe an unreported innate immune pathway and suggest that mutation or antagonism of the E3 ligase HECTD2 results in reduced severity of lung inflammation by selectively modulating the abundance of the anti-inflammatory protein PIAS1 (show PIAS1 Proteins)
Hectd2 is identified as a quantitative trait gene for prion disease inc (show PRNP Proteins)ubation time in mice.
A major biological consequence of upregulation of miR (show MLXIP Proteins)-221 is reprogramming of androgen receptor (show AR Proteins) signaling via downregulation of HECTD2 and RAB1A (show RAB1A Proteins).
HECTD2 polymorphisms are not associated with genetic susceptibility to sporadic Creutzfeldt-Jakob disease in a Korean population
HECTD2 haplotypes are associated with the susceptibility to human prion (show PRNP Proteins) diseases.
The common haplotypes of HECTD2, tagged by rs12249854, are not associated with susceptibility to late onset Alzheimer's disease
Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity).
HECT domain containing 2
, probable E3 ubiquitin-protein ligase HECTD2
, Probable E3 ubiquitin-protein ligase HECTD2
, HECT domain-containing protein 2