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HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 Proteins (HERC6)

HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). Additionally we are shipping HERC6 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HERC6 55008 Q8IVU3
Rat HERC6 HERC6 362376  
HERC6 67138  
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Top HERC6 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HERC6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6) Interaction Partners

Human HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6) interaction partners

  1. HERC6 ancestor emerged in nematodes and that the family expanded throughout evolution. The mRNA expression pattern was found to be diverse in selected tissues and cells

Mouse (Murine) HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6) interaction partners

  1. These results suggest that in addition to promoting protein ISGylation, Herc6 has a novel and protein ISGylation-independent function in the male reproductive system.

  2. Data show that the HerC6 N-terminal RCC1 (show RCC1 Proteins)-like domain (RLD) allows ISG15 (show ISG15 Proteins) conjugation.

  3. mHERC6 is essential for endogenous murine ISGylation and thus represents the dominant ISG15 (show ISG15 Proteins) E3 ligase in mice.

  4. Expression of the Herc5-mediated ubiquitin-like protein ISGylation system can distinctly potentiate interferon-beta (show IFNB1 Proteins)-induced antiviral effects against influenza A virus.

HERC6 Protein Profile

Protein Summary

HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005

Gene names and symbols associated with HERC6

  • HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 (HERC6)
  • HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 (Herc6)
  • hect domain and RLD 6 (Herc6)
  • 1700121D12Rik protein
  • 2510038N07Rik protein
  • 4930427L17Rik protein
  • AI451296 protein
  • CEB1 protein
  • Herc5 protein

Protein level used designations for HERC6

HECT domain and RCC1-like domain-containing protein 6 , hect domain and RLD 6 , potential ubiquitin ligase , probable E3 ubiquitin-protein ligase HERC6 , E3 ISG15--protein ligase Herc6 , hect domain and RLD 5

GENE ID SPECIES
55008 Homo sapiens
362376 Rattus norvegicus
67138 Mus musculus
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