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anti-HLA Class II DR beta 1 (HLA-DRB1) Antibodies

HLA-DRB3 belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA Class II DR beta 1 Proteins (25) and HLA Class II DR beta 1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DRB1 3123 P01912,P01911,Q29974
HLA-DRB1    
HLA-DRB1    
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Top anti-HLA Class II DR beta 1 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HLA-DRB1 Antibody (N-term) (ABIN390872) in Wi... Formalin-fixed and paraffin-embedded human brain tissue reacted with H... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HLA-DRB1 Antibody (N-term) in WiDr cell line ... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$342.43
Details
Human Mouse Un-conjugated FACS, ICFC 100 μg Log in to see 10 to 12 Days
$298.95
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE anti... IHC-P Image Immunohistochemical analysis of paraffin-embedded human lu... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLA-DRB1 expression in transfected 293T cell ... HLA-DRB1 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB1... 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 6 to 11 Days
$485.71
Details

HLA-DRB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Arabidopsis thaliana

Top referenced anti-HLA Class II DR beta 1 Antibodies

  1. Human Monoclonal HLA-DRB1 Primary Antibody for FACS, ICFC - ABIN2665043 : Balandraud, Picard, Reviron, Landais, Toussirot, Lambert, Telle, Charpin, Wendling, Pardoux, Auger, Roudier: HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis. in PLoS ONE 2013 (PubMed)
    Show all 10 references for ABIN2665043

  2. Human Monoclonal HLA-DRB1 Primary Antibody for FACS - ABIN2662751 : Foo, Smedby, Akers, Berglund, Irwan, Jia, Li, Conde, Darabi, Bracci, Melbye, Adami, Glimelius, Khor, Hjalgrim, Padyukov, Humphreys, Enblad, Skibola, de Bakker, Liu: Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk. in American journal of human genetics 2013 (PubMed)
    Show all 10 references for ABIN2662751

  3. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN1944757 : Tonnelle, DeMars, Long: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. in The EMBO journal 1986 (PubMed)
    Show all 5 references for ABIN1944757

  4. Human Monoclonal HLA-DRB1 Primary Antibody for EIA, FACS - ABIN238469 : Klotz: Ligand-receptor complexes: origin and development of the concept. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN238469

  5. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN516510 : Cao, Schmitz, Yang, Hogan, Bunch, Hu, Jennette, Berg, Arnett, Jennette, Falk, Preston: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. in Journal of the American Society of Nephrology : JASN 2011 (PubMed)

More Antibodies against HLA Class II DR beta 1 Interaction Partners

Human HLA Class II DR beta 1 (HLA-DRB1) interaction partners

  1. HLA-DRB1*04 alleles are associated with pulmonary tuberculosis;the subtype HLA-DRB1*04:11:01 (p = 0.0019; OR = 2.23; 95% CI = 1.34 to 3.70) was associated with susceptibility to disease, while DRB1 (show RBM45 Antibodies)*04:07:01 (p<0.0001; OR = 0.02; 95% CI = 0.001 to 0.33)to protection.

  2. The negative association we describe here supports the idea that the HLA-DRB1 *13 allele, possibly by its specific structural features, may as well confer resistance to several other AIDs.

  3. Data indicate that the strongest risk factor for systemic juvenile idiopathic arthritis (sJIA) was HLA-DRB1*11.

  4. alleles DRB1 (show RBM45 Antibodies)*01:01, DQ4, DQ7 and DQ8 are considered as susceptible to egg allergy

  5. One of the associated variants was also found to be linked with increased expression of MERTK (show MERTK Antibodies) in monocytes and higher expression of MERTK (show MERTK Antibodies) was associated with either increased or decreased risk of developing MS, dependent upon HLA-DRB1*15:01 status.

  6. This study shows the universal applicability of the RNA-based sequencing approach to identify full-length coding sequences and to define the polymorphic content of HLA-DRB1 alleles.

  7. A limit to the divergent allele advantage model supported by variable pathogen recognition across HLA-DRB1 allele lineages.

  8. We found association of three variants in the region harboring genes encoding the class II human leukocyte antigens (HLAs): both located between HLA-DQA1 (show HLA-DQA2 Antibodies) and HLA-DRB1

  9. HLA-DRB1 variants better accounted for the association between MHC (show HLAE Antibodies) and susceptibility to RA and SLE than did 3 other HLA-DRB (show HLA-DRB5 Antibodies) variants.

  10. The HLA-DRB1*15 allele, the A*01/B*08/DRB1*03 haplotypes, and the homozygosity of HLA-A*01 and HLA-A*02 may play a presumptive predisposing factor in Acute Myeloblastic Leukemia.

HLA Class II DR beta 1 (HLA-DRB1) Antigen Profile

Protein Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Gene names and symbols associated with HLA-DRB1

  • major histocompatibility complex, class II, DR beta 1 (hla-drb1) antibody
  • major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) antibody
  • DRB1 antibody
  • DRw10 antibody
  • HLA-DR1B antibody
  • HLA-DRB antibody
  • MGC108235 antibody
  • SS1 antibody

Protein level used designations for HLA-DRB1

major histocompatibility complex, class II, DR beta 1 , DW2.2/DR2.2 , HLA class II histocompatibility antigen, DR-1 beta chain , MHC class II HLA-DR beta 1 chain , MHC class II HLA-DR-beta cell surface glycoprotein , MHC class II HLA-DRw10-beta , MHC class II antigen , human leucocyte antigen DRB1 , lymphocyte antigen DRB1

GENE ID SPECIES
734125 Xenopus (Silurana) tropicalis
3123 Homo sapiens
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