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HLA-DRB1 belongs to the HLA class II beta chain paralogs. Additionally we are shipping HLA-DRB1 Proteins (25) and HLA-DRB1 Kits (7) and many more products for this protein.
Showing 10 out of 198 products:
Human Monoclonal HLA-DRB1 Primary Antibody for FACS, ICFC - ABIN2665043
Balandraud, Picard, Reviron, Landais, Toussirot, Lambert, Telle, Charpin, Wendling, Pardoux, Auger, Roudier: HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis. in PLoS ONE 2013
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Human Monoclonal HLA-DRB1 Primary Antibody for FACS - ABIN2662751
Foo, Smedby, Akers, Berglund, Irwan, Jia, Li, Conde, Darabi, Bracci, Melbye, Adami, Glimelius, Khor, Hjalgrim, Padyukov, Humphreys, Enblad, Skibola, de Bakker, Liu: Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk. in American journal of human genetics 2013
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Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN1944757
Tonnelle, DeMars, Long: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. in The EMBO journal 1986
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Human Monoclonal HLA-DRB1 Primary Antibody for EIA, FACS - ABIN238469
Klotz: Ligand-receptor complexes: origin and development of the concept. in The Journal of biological chemistry 2003
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Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN516510
Cao, Schmitz, Yang, Hogan, Bunch, Hu, Jennette, Berg, Arnett, Jennette, Falk, Preston: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. in Journal of the American Society of Nephrology : JASN 2011
The HLA-DR observed on CD4 (show CD4 Antibodies)+ T cells was almost exclusively cell surface-associated, while for autologous CD19 (show CD19 Antibodies)+ B cells, the protein could be located in the plasma membrane as well as in the cytoplasm.
HLA-DRB1*04:02, DRB1 (show RBM45 Antibodies)*14:04, HLA-DQB1 (show HLA-DQB1 Antibodies)* 03:02 and DQB1*05:03 alleles and HLA-DRB1*04:02-DQB1*03:02 and HLA-DRB1*14:04-DQB1*05:03 haplotypes are genetic markers for susceptibility for pemphigus vulgaris (show DSG3 Antibodies), while DRB1 (show RBM45 Antibodies)*11 allelic group appears protective in Serbian population.
These findings indicate the role of HLA-DRB (show HLA-DRB5 Antibodies) haplotypes in AIH susceptibility and protection, in the Iranian population.
HLA-DRB1*14 and DQB1*05 were associated with anti-MUSK (show MUSK Antibodies) antibody-positive myasthenia gravis.
ur results indicated that HLA-DRB1*04:05, *04:03, *04:06 and SE alleles might be susceptibility allele for Rheumatoid arthritis in Chinese Han population of Shaanxi province, northwest of China
Valpha2.3+Vbeta22+ CD4 (show CD4 Antibodies)+ T-cells accumulate in the lungs of HLA-DRB1*03+ patients with pulmonary sarcoidosis
Results identified a novel HLA class II association for flupirtine-induced liver injury (DILI) showing HLA-DRB1*16: 01 and DQB1*05: 02 as novel genetic risk factor for DILI and confirming the important contribution of HLA genotype towards the risk of DILI generally.
HLA-DRB1*11 and HLA-DRB1*14 may be used to predict the susceptibility to Helicobacter pylori infection in children with idiopathic thrombocytopenic purpura
The new alleles (DRB1*03:112, DQB1*03:02:16 and DQB1*03:139)were found after the sequence-based typing of 32 530 random UK European routine blood donors suggesting that each has a maximum carriage frequency of 0.0031% in the blood donor population resident in Wales.
HLA-DRB1*04 (OR 1.24, 95%CI 1.00-1.55, P = 0.0494), HLA-DRB1*08 (OR 1.45, 95%CI 1.14-1.86, P = 0.0030) and HLA-DRB1*16 (OR 1.39, 95%CI 1.04-1.87, P = 0.0269) were significantly associated with increased tuberculosis occurrence (Meta-Analysis)
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.
major histocompatibility complex, class II, DR beta 1
, HLA class II histocompatibility antigen, DR-1 beta chain
, MHC class II HLA-DR beta 1 chain
, MHC class II HLA-DR-beta cell surface glycoprotein
, MHC class II HLA-DRw10-beta
, MHC class II antigen
, human leucocyte antigen DRB1
, lymphocyte antigen DRB1