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anti-HLA Class II DR beta 1 (HLA-DRB1) Antibodies

HLA-DRB1 belongs to the HLA class II beta chain paralogs. Additionally we are shipping HLA-DRB1 Proteins (25) and HLA-DRB1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DRB1 3123 P01912,P01911,Q29974
HLA-DRB1    
HLA-DRB1    
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Top anti-HLA-DRB1 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HLA-DRB1 Antibody (N-term) (ABIN390872) in WiDr cell line lysates (35 µg/lane). HLA-DRB1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with HLA-DRB1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HLA-DRB1 Antibody (N-term) in WiDr cell line lysates (35 µg/lane). HLA-DRB1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$342.43
Details
Human Mouse Un-conjugated FACS, ICFC 100 μg Log in to see 10 to 12 Days
$298.95
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma, using HLA-DRB1, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLA-DRB1 expression in transfected 293T cell line by HLA-DRB1 MaxPab polyclonal antibody.Lane 1: HLA-DRB1 transfected lysate(29.26 KDa).Lane 2: Non-transfected lysate. HLA-DRB1 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB1 expression in human spleen. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 6 to 11 Days
$485.71
Details

HLA-DRB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
,
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Mouse (Murine)


Arabidopsis thaliana


Top referenced anti-HLA-DRB1 Antibodies

  1. Human Monoclonal HLA-DRB1 Primary Antibody for FACS, ICFC - ABIN2665043 : Balandraud, Picard, Reviron, Landais, Toussirot, Lambert, Telle, Charpin, Wendling, Pardoux, Auger, Roudier: HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis. in PLoS ONE 2013 (PubMed)
    Show all 10 references for ABIN2665043

  2. Human Monoclonal HLA-DRB1 Primary Antibody for FACS - ABIN2662751 : Foo, Smedby, Akers, Berglund, Irwan, Jia, Li, Conde, Darabi, Bracci, Melbye, Adami, Glimelius, Khor, Hjalgrim, Padyukov, Humphreys, Enblad, Skibola, de Bakker, Liu: Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk. in American journal of human genetics 2013 (PubMed)
    Show all 10 references for ABIN2662751

  3. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN1944757 : Tonnelle, DeMars, Long: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. in The EMBO journal 1986 (PubMed)
    Show all 5 references for ABIN1944757

  4. Human Monoclonal HLA-DRB1 Primary Antibody for EIA, FACS - ABIN238469 : Klotz: Ligand-receptor complexes: origin and development of the concept. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN238469

  5. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN516510 : Cao, Schmitz, Yang, Hogan, Bunch, Hu, Jennette, Berg, Arnett, Jennette, Falk, Preston: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. in Journal of the American Society of Nephrology : JASN 2011 (PubMed)

More Antibodies against HLA-DRB1 Interaction Partners

Human HLA Class II DR beta 1 (HLA-DRB1) interaction partners

  1. The carrier frequency of the HLA-DRB1*01 was higher in mixed connective tissue disease patients compared with controls, although the differences were not statistically significant.

  2. Significant increases in type 1 diabetes risk resulted from harboring the alleles HLA-DRB1*03:01 and HLA-DRB1*04:05. (Meta-analysis)

  3. the HLA-DRB1* haplotype appeared complementary with current serologic tools to predict good and poor responders in a treat to target strategy.

  4. HLA-DRB1*03 is associated with microalbuminuria in type 1 diabetes. HLA-DRB1*04 had no association.

  5. Positive association of DRB1 (show RBM45 Antibodies)*03 allele with Atopic Bronchial Asthma has been found in Uzbek population.

  6. DRB1*04 (DR4) (41/214 vs 42/400, Pc = 0.042, OR = 2.02, 95% CI 1.27-3.22) and DQB1*0302 (35/214 vs 32/400, Pc = 0.014, OR = 2.25, 95% CI 1.35-3.75) had significant positive association with AChR MG compared to controls, and

  7. In late-onset SLE, HLA DR17 (DR3 (show TNFRSF25 Antibodies)) was found more frequently compared with individuals without autoimmune disease.

  8. The observed positive association between integrated HIV-1 DNA load and frequency of CD8 (show CD8A Antibodies)(+)DR/DP/DQ(+) cells indicates that a close correlation between HIV persistence and immune activation continues during consistently suppressive therapy.

  9. HLA-DRB1*04 alleles are associated with pulmonary tuberculosis;the subtype HLA-DRB1*04:11:01 (p = 0.0019; OR = 2.23; 95% CI = 1.34 to 3.70) was associated with susceptibility to disease, while DRB1 (show RBM45 Antibodies)*04:07:01 (p<0.0001; OR = 0.02; 95% CI = 0.001 to 0.33)to protection.

  10. The negative association we describe here supports the idea that the HLA-DRB1 *13 allele, possibly by its specific structural features, may as well confer resistance to several other AIDs.

HLA-DRB1 Antigen Profile

Protein Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Gene names and symbols associated with HLA-DRB1

  • major histocompatibility complex, class II, DR beta 1 (hla-drb1) antibody
  • major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) antibody
  • DRB1 antibody
  • DRw10 antibody
  • HLA-DR1B antibody
  • HLA-DRB antibody
  • MGC108235 antibody
  • SS1 antibody

Protein level used designations for HLA-DRB1

major histocompatibility complex, class II, DR beta 1 , DW2.2/DR2.2 , HLA class II histocompatibility antigen, DR-1 beta chain , MHC class II HLA-DR beta 1 chain , MHC class II HLA-DR-beta cell surface glycoprotein , MHC class II HLA-DRw10-beta , MHC class II antigen , human leucocyte antigen DRB1 , lymphocyte antigen DRB1

GENE ID SPECIES
734125 Xenopus (Silurana) tropicalis
3123 Homo sapiens
Selected quality suppliers for anti-HLA-DRB1 (HLA-DRB1) Antibodies
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