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anti-HLA Class II DR beta 1 (HLA-DRB1) Antibodies

HLA-DRB1 belongs to the HLA class II beta chain paralogs. Additionally we are shipping HLA-DRB1 Proteins (25) and HLA-DRB1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DRB1 3123 P01912 , P01911 , Q29974
HLA-DRB1    
HLA-DRB1    
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Top anti-HLA-DRB1 Antibodies at antibodies-online.com

Showing 10 out of 198 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HLA-DRB1 Antibody (N-term) (ABIN390872) in WiDr cell line lysates (35 µg/lane). HLA-DRB1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with HLA-DRB1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HLA-DRB1 Antibody (N-term) in WiDr cell line lysates (35 µg/lane). HLA-DRB1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$342.43
Details
Human Mouse Un-conjugated FACS, ICFC 100 μg Log in to see 10 to 12 Days
$298.95
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma, using HLA-DRB1, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLA-DRB1 expression in transfected 293T cell line by HLA-DRB1 MaxPab polyclonal antibody.Lane 1: HLA-DRB1 transfected lysate(29.26 KDa).Lane 2: Non-transfected lysate. HLA-DRB1 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB1 expression in human spleen. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: HLA DRB1 Antibody [NBP2-16853] - Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: HLA DRB1 Antibody [NBP2-16853] - Immunohistochemical analysis of paraffin-embedded lung AdCA, using antibody at 1:500 dilution. 0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of HLA-DRB1 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo Western blot analysis of HLA-DRB1 expression in MCF7 (A), mouse spleen (B), mouse heart (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

HLA-DRB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Baboon


Top referenced anti-HLA-DRB1 Antibodies

  1. Human Monoclonal HLA-DRB1 Primary Antibody for FACS, ICFC - ABIN2665043 : Balandraud, Picard, Reviron, Landais, Toussirot, Lambert, Telle, Charpin, Wendling, Pardoux, Auger, Roudier: HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis. in PLoS ONE 2013 (PubMed)
    Show all 10 references for ABIN2665043

  2. Human Monoclonal HLA-DRB1 Primary Antibody for FACS - ABIN2662751 : Foo, Smedby, Akers, Berglund, Irwan, Jia, Li, Conde, Darabi, Bracci, Melbye, Adami, Glimelius, Khor, Hjalgrim, Padyukov, Humphreys, Enblad, Skibola, de Bakker, Liu: Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk. in American journal of human genetics 2013 (PubMed)
    Show all 10 references for ABIN2662751

  3. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN1944757 : Tonnelle, DeMars, Long: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. in The EMBO journal 1986 (PubMed)
    Show all 5 references for ABIN1944757

  4. Human Monoclonal HLA-DRB1 Primary Antibody for EIA, FACS - ABIN238469 : Klotz: Ligand-receptor complexes: origin and development of the concept. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN238469

  5. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN516510 : Cao, Schmitz, Yang, Hogan, Bunch, Hu, Jennette, Berg, Arnett, Jennette, Falk, Preston: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. in Journal of the American Society of Nephrology : JASN 2011 (PubMed)

More Antibodies against HLA-DRB1 Interaction Partners

Human HLA Class II DR beta 1 (HLA-DRB1) interaction partners

  1. Subjects with HLA DRB1*04:05-DQB1*04:01 haplotype were more likely to show weight loss than those without in type 1 diabetes.

  2. Report association of HLA-DRB1*07 haplotype with steroid resistant nephrotic syndrome.

  3. HLA-DRB1 *1 and *11 allele polymorphisms were protective factors, *12 and *14 allele polymorphisms were risk factors for hepatocellular carcinoma development.

  4. X-rays of hands, feet and knees showed characteristic features of erosive hand osteoarthritis (EHOA), psoriatic arthritis (PsA) and chondrocalcinosis (CC)/pseudogout. Furthermore, HLA typing evinces the presence of HLA C*06; DRB*01 07 and HLA C*07; DRB*01 *11 alleles, respectively, predisposing factors of these inflammatory diseases. [review]

  5. A number of HLA-DRB1 alleles and haplotypes showed susceptible (DRB1 (show RBM45 Antibodies)*11, DRB1 (show RBM45 Antibodies)*04 DRB1 (show RBM45 Antibodies)*03) and protective (DRB1 (show RBM45 Antibodies)*10) association(s) in T2DM patients from south India.

  6. HLA-DRB1 allele polymorphisms are associated with nasopharyngeal carcinoma.

  7. this study shows that none of the HLA-DRB*1 genotypes are observed to increase the susceptibility of North Indian children to Henoch-Schonlein purpura

  8. Combination of HLA-B*15:01 and DRB1 (show RBM45 Antibodies)*15:01 is associated with interstitial lung disease in Japanese patients with advanced pancreatic cancer receiving gemcitabine plus erlotinib.

  9. The HLA-DR observed on CD4 (show CD4 Antibodies)+ T cells was almost exclusively cell surface-associated, while for autologous CD19 (show CD19 Antibodies)+ B cells, the protein could be located in the plasma membrane as well as in the cytoplasm.

  10. HLA-DRB1*04:02, DRB1 (show RBM45 Antibodies)*14:04, HLA-DQB1 (show HLA-DQB1 Antibodies)* 03:02 and DQB1*05:03 alleles and HLA-DRB1*04:02-DQB1*03:02 and HLA-DRB1*14:04-DQB1*05:03 haplotypes are genetic markers for susceptibility for pemphigus vulgaris (show DSG3 Antibodies), while DRB1 (show RBM45 Antibodies)*11 allelic group appears protective in Serbian population.

HLA-DRB1 Antigen Profile

Protein Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Gene names and symbols associated with HLA-DRB1

  • major histocompatibility complex, class II, DR beta 1 (hla-drb1) antibody
  • major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) antibody
  • DRB1 antibody
  • DRw10 antibody
  • HLA-DR1B antibody
  • HLA-DRB antibody
  • MGC108235 antibody
  • SS1 antibody

Protein level used designations for HLA-DRB1

major histocompatibility complex, class II, DR beta 1 , DW2.2/DR2.2 , HLA class II histocompatibility antigen, DR-1 beta chain , MHC class II HLA-DR beta 1 chain , MHC class II HLA-DR-beta cell surface glycoprotein , MHC class II HLA-DRw10-beta , MHC class II antigen , human leucocyte antigen DRB1 , lymphocyte antigen DRB1

GENE ID SPECIES
734125 Xenopus (Silurana) tropicalis
3123 Homo sapiens
Selected quality suppliers for anti-HLA-DRB1 (HLA-DRB1) Antibodies
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