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Core component of nucleosome.
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Plant Polyclonal HTR12 Primary Antibody for ELISA, ICC - ABIN438687
Pontvianne, Carpentier, Durut, Pavlištová, Jaške, Schořová, Parrinello, Rohmer, Pikaard, Fojtová, Fajkus, Sáez-Vásquez: Identification of Nucleolus-Associated Chromatin Domains Reveals a Role for the Nucleolus in 3D Organization of the A. thaliana Genome. in Cell reports 2016
Acetylation of histone H3 lysine 23 is localized to promoters and correlates with endogenous ecdysone induced gene activation.
structural, energetic, and mutational analyses of the complex between the Drosophila HP1 (show CBX5 Antibodies) chromodomain and the histone H3 tail with a methyllysine at residue 9, a modification associated with epigenetic silencing, are presented
In Su(var)3-9 (show EIF2S3 Antibodies) null mutants, H3-K9 methylation at chromocentre heterochromatin is strongly reduced, indicating that SU(VAR)3-9 (show EIF2S3 Antibodies) is the major heterochromatin-specific HMTase in Drosophila.
these studies establish a link between histone methylation and Polycomb (show CBX2 Antibodies) group-mediated gene silencing
Mutants in protein phosphatase type 2A (PP2A (show PPP2R2B Antibodies)) also display reduced genome-wide H3 dephosphorylation, and sites of H3 phosphorylation that do not contain heat shock genes remain transcriptionally active during heat shock in PP2A (show PPP2R2B Antibodies) mutants.
Arabidopsis KNL2 (show MIS18BP1 Antibodies) colocalizes with cenH3 (show CENPA Antibodies) and is associated with centromeres during all stages of the mitotic cell cycle, except from metaphase to mid-anaphase.
Reduced endogenous CENH3 (show CENPA Antibodies) and lack of meiotic incorporation of EYFP-CENH3 (show CENPA Antibodies)(C) lead to reduced fertility caused by insufficient CENH3 (show CENPA Antibodies) loading to the centromeres of meiotic chromosomes, subsequent lagging of chromosomes and formation of micronuclei.
Silencing of the AtTERT (show TERT Antibodies) gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment.
CENH3 (show CENPA Antibodies) is expressed in dividing tissues and is CENH3 (show CENPA Antibodies) is transcriptionally regulated by E2F/DP (show E2F1 Antibodies) transcription factors.
Deposition of Arabidopsis CENH3 (show CENPA Antibodies) takes place at centromeres during G2.
Meiosis-specific loading of the centromere-specific histone CENH3 (show CENPA Antibodies) in Arabidopsis thaliana
study concludes that CENH3 (show CENPA Antibodies) function in A. thaliana, an organism with large tandem repeat centromeres, has stringent requirements for functional complementation in mitosis
Alignment of CENH3 (show CENPA Antibodies) sequences revealed that the tested species share only three amino acids at loop1 region: threonine2, arginine12 and alanine15
cenh3 (show CENPA Antibodies) null mutants expressing altered CENH3 (show CENPA Antibodies) proteins are crossed to wild type, chromosomes from the mutant are eliminated, producing haploid progeny
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.