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Heat Shock 70kDa Protein 1A Proteins (HSPA1A)

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. Additionally we are shipping HSPA1A Antibodies (138) and HSPA1A Kits (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HSPA1A HSPA1A 24472 Q07439
HSPA1A 3303 P08107
HSPA1A 193740 Q61696
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Top HSPA1A Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
HOST_Escherichia coli (E. coli) Cow His tag 100 μg Log in to see 11 to 13 Days
$563.20
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$715.97
Details
HOST_Escherichia coli (E. coli) Cow Un-conjugated   100 μg Log in to see 9 to 19 Days
$747.45
Details
HOST_Sf-9 Cells Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$460.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HSPA1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,

Mouse (Murine)

Top referenced HSPA1A Proteins

  1. Human HSPA1A Protein expressed in Baculovirus infected Insect Cells - ABIN2004489 : Heck, Schöler, de Bittencourt: HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain? in Cell biochemistry and function 2011 (PubMed)

More Proteins for Heat Shock 70kDa Protein 1A (HSPA1A) Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. hsp72 was more potent than hsc73 (show HSPA8 Proteins) in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. HSP72 blocks fibroblast activation and proliferation in renal fibrosis via targeting the STAT3 (show STAT3 Proteins) pathway and may serve as a novel therapeutic agent for chronic kidney disease regardless of the etiology

  2. Studies suggest that heat shock protein 72/70 (Hsp70 (show HSP70 Proteins) proteins) are beneficial to the patient in slowing the onset of neurodegenerative disorders.

  3. P53 (show TP53 Proteins) could be used to distinguish early HCC (show FAM126A Proteins) from advanced hepatocellular carcinoma, but HSP70 (show HSP70 Proteins) cannot

  4. cytokines, not being influenced by HSP72 polymorphisms, cortisol, or illness severity. Gln may depress l/mHSP72 after LPS (show IRF6 Proteins) exposure and enhance them after HS induction, but it may not affect early induced HSP72 mRNA.

  5. heat acclimation reduces physiological strain, and the transcription of HSP72, but not HSP90alpha (show HSP90AA2 Proteins) mRNA in acute normobaric hypoxia.

  6. Hsp72 (HSPA1A) prevents h-IAPP (show IAPP Proteins) aggregation and toxicity.

  7. HSPA1A (rs1043618) is associated with a decreased risk of idiopathic pulmonary fibrosis in a Mexican population.

  8. Phosphorylation of HSF1 (show HSF1 Proteins) at Ser230 is responsible for Hsp70-1 upregulation during coxsackieviral infection.

  9. Lysine methylation of HSPA1 differs between metastatic breast and ovarian carcinoma.

  10. Together, these results implicate HSP70-1A as a novel angiogenic regulator.

Cow (Bovine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. Inhibition of Hsp70 (show HSP70 Proteins) by using the Hsp70 (show HSP70 Proteins) inhibitor KNK437 or knock down Hsp70 (show HSP70 Proteins) using siRNA exaggerated and overexpression of Hsp70 (show HSP70 Proteins) prevented the second phase disruption of lung endothelial integrity.

  2. Prostaglandin E synthase (show PTGES Proteins) interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cells.

  3. Hsp70-1A is a biomarker of low beef tenderness across the cattle breeds. [HSP70-1a]

  4. More DNMT1 (show DNMT1 Proteins) mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 Proteins) mRNA was present at highest levels in transgenic SCNT embryos.

  5. the promoter region of bovine hsp70.1 gene is polymorphic and may be useful in selection of dairy cows for relatively better thermotolerance and higher milk production.

  6. Heat shock increased both HSP70 and IFNT expression in blastocysts.

  7. This study showed that Hsp70 (show HSP70 Proteins) concentration is a reliable indicator of chronic stress but is not a reliable indicator of a single stressor when animals are exposed to multiple chronic stressors.

  8. the presence of SNPs (C/- and G/T) in the 5'-UTR region of inducible Hsp70.1 ameliorates HS response and tolerance to heat of bovine peripheral blood mononuclear cells

  9. that HSC70 (show HSPA8 Proteins) preconditioning (1) attenuates the TNF-alpha (show TNF Proteins) response to endotoxin in macrophages in vitro, (2) induces cardiac functional tolerance to endotoxin and (3) reduces NF-kappaB (show NFKB1 Proteins) activity, and TNF-alpha (show TNF Proteins) and ICAM-1 (show ICAM1 Proteins) levels in heart tissue.

  10. A new SNP in the 3'-UTR of the hsp 70-1 (show HSP70 Proteins) gene in Bos taurus and Bos indicus

Zebrafish Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. Perturbation of the HSP70-HSP90 (show HSP90 Proteins) heat-shock protein axis stimulates degradation of endothelial VEGFR2 (show KDR Proteins).

  2. HSP70, the earliest induced gene in the zebrafish retina after optic nerve injury, is a crucial factor for retinal ganglion cell survival and optic nerve regeneration.

  3. HSP70 mRNA and protein were increased 2.2 fold at 0.5-24 hours after optic nerve injury then returned to control level.

  4. hsp70 is required for embryonic lens development.

  5. data suggest that HSF1 (show HSF1 Proteins) is involved in regulating constitutive lens specific expression of hsp70 in the embryonic zebrafish.

  6. in rheumatoid arthritis Significantly higher Hsp70 (heat shock protein 70 (show HSP70 Proteins)) expression was found on synovial cells than on skin fibroblasts; high co-expression of CD91 (show LRP1 Proteins) and Hsp70 on RA synovial cells

  7. These results demonstrate that induction of Hsp70 in response to heat stress is dependent on ERK (show MAPK1 Proteins) activation in Pac2 (show PSMG2 Proteins) cells.

  8. Hsp70 levels above the median were associated with a higher rate of progression to the accelerated/blast phase and a tendency toward shorter survival

Mouse (Murine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. HspA1A-phosphoinositide binding is complex yet specific, is mediated by both electrostatic and hydrophobic interactions, is not related to the lipid-head charge, and depends on the physicochemical properties of the lipid.

  2. The protective mechanism of HAS2 (show HAS2 Proteins) involves an increased expression of the heat-shock protein Hsp72, a chaperone with antiapoptotic activity

  3. HspA1A embeds in membranes when bound to liposomes composed of cardiolipin and sulfatide.The two domains of HspA1A differentially bind to lipids, such as cardiolipin and sulfatide.

  4. Knockdown lines were created for specific DSBs in regions of the chromosome that are coding for HSPA1A. Clonogenic cell survival was significantly lower in irradiated Hsp70 KD cells with low mHsp70 expression, than in ctrl cells.

  5. genetic manipulation of Hsp72 does not lead to alterations in metabolic processes in cardiac tissue under resting conditions, but identifies mouse strain-specific differences in cardiac lipid accumulation and insulin (show INS Proteins)-stimulated glucose clearance.

  6. Data indicate that heat shock protein 70 (Hsp70 (show HSP70 Proteins)) is higher in nuclear protein 1 (Nupr1 (show NUPR1 Proteins)+/-) haplodeficient mice, concomitant with improved insulin (show INS Proteins) sensitivity.

  7. HuR (show ELAVL1 Proteins) does not play a role in APA (show ENPEP Proteins) of the Hsp70.3 mRNA, and these two regulatory events appear to be mutually exclusive regulators of Hsp70.3 expression

  8. Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin (show INS Proteins) resistance.

  9. Activation of HSP-72 upregulates lung injury associated with Pseudomonas aeruginosa pneumonia.

  10. In HSP72 knockout mice, impaired Parkin (show PARK2 Proteins) action was associated with retention of enlarged, dysmorphic mitochondria and paralleled by reduced muscle respiratory capacity, lipid accumulation, and muscle insulin (show INS Proteins) resistance.

Pig (Porcine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. overexpression of the HSP70.2 (show HSPA2 Proteins) gene in multiple organs of transgenic mice improves survival during heatstroke by reducing hyperthermia, circulatory shock, and cerebral ischemia and damage

HSPA1A Protein Profile

Protein Summary

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Gene names and symbols associated with HSPA1A

  • heat shock 70kDa protein 1A (HSPA1A)
  • heat shock 70kDa protein 1A (hspa1a)
  • heat shock 70kD protein 1A (Hspa1a)
  • heat shock cognate 70-kd protein (hsp70)
  • heat shock protein 1A (Hspa1a)
  • heat shock protein 70.2 (HSP70.2)
  • hsp68 protein
  • HSP70 protein
  • HSP70-1 protein
  • HSP70-1A protein
  • HSP70-2 protein
  • Hsp70-3 protein
  • hsp70-4 protein
  • Hsp70.3 protein
  • hsp70A1 protein
  • HSP70I protein
  • Hsp72 protein
  • HSPA1 protein
  • HSPA1A protein
  • HSPA1B protein
  • HSPA2 protein

Protein level used designations for HSPA1A

heat shock 70kDa protein 1A , HSP70-1/HSP70-2 , HSP70.1/2 , HSP70.1/HSP70.2 , heat shock 70 kDa protein 1/2 , heat shock 70 kDa protein 1A/1B , heat shock protein 70-1 , dnaK-type molecular chaperone HSP70-1 , heat shock 70kD protein 1A , heat shock-induced protein , 70 kda heat shock protein-2 , HSP70.2 , chaperone , heat shock 70 kD protein 2 , heat shock 70 kDa protein 1B , heat shock 70 kDa protein 2 , heat shock 70kDa protein 1B , heat-shock 70-kilodalton protein 1B , HSP70.1 , heat shock 70 kD protein 1 , heat shock 70 kDa protein 1 , heat shock 70 kDa protein 1A , heat-shock 70-kilodalton protein 1A , etID309743.10 , stress protein HSP70 , 68 kDa heat shock protein , heat shock 70 kDa protein 3 , heat shock protein, 70 kDa 3 , inducible heat shock protein 70

GENE ID SPECIES
100023597 Monodelphis domestica
100554002 Anolis carolinensis
100608888 Pan troglodytes
24472 Rattus norvegicus
100381020 Xenopus laevis
3303 Homo sapiens
100354037 Oryctolagus cuniculus
282254 Bos taurus
100913152 Ovis aries
281825 Bos taurus
30671 Danio rerio
193740 Mus musculus
396648 Sus scrofa
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