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Heat Shock 70kDa Protein 9 (Mortalin) Proteins (HSPA9)

HSPA9 encodes a member of the heat shock protein 70 gene family. Additionally we are shipping HSPA9 Antibodies (161) and HSPA9 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSPA9 3313 P38646
HSPA9 15526 P38647
HSPA9 291671  
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Top HSPA9 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$3,014.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,831.67
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 3 to 4 Days
$190.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$273.57
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

HSPA9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced HSPA9 Proteins

  1. Human HSPA9 Protein expressed in Escherichia coli (E. coli) - ABIN666870 : Deocaris, Widodo, Ishii, Kaul, Wadhwa: Functional significance of minor structural and expression changes in stress chaperone mortalin. in Annals of the New York Academy of Sciences 2007 (PubMed)
    Show all 2 references for ABIN666870

More Proteins for Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Hspa9 is an important mediator for pronephros development through modulation of pax8 (show PAX8 Proteins). Mitochondrial functions of hspa9 are likely to be involved in specification of pronephric cell fate.

Human Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Study shows that Mortalin is upregulated in breast cancer, and may be a useful poor prognostic biomarker for patients with breast cancer.

  2. This study showed that human post-mortem tissue indicated co-localization of mortalin within astrocytes.

  3. Biallelic mutations in HSPA9 are associated with the EVEN-PLUS syndrome of congenital malformations and skeletal dysplasia.

  4. veratridine enhances transactivation of UBXN2A, resulting in upregulation of UBXN2A in the cytoplasm, where UBXN2A binds and inhibits the oncoprotein mortalin-2

  5. Impaired stoichiometry between mtHsp40 and mtHsp70 promotes Opa1L cleavage, leading to cristae opening, decreased OXPHOS, and triggering of mitochondrial fragmentation after reduction in their chaperone function.

  6. mutations in HSPA9 result in congenital sideroblastic anemia inherited as an autosomal recessive trait

  7. Expression of mortalin decreased significantly in dopaminergic cells overexpressing A53T alpha-syn

  8. Results present the functional structure of human mortalin showing at least two domains and interacts with adenosine nucleotides with high affinity depending on the presence of Mg2 (show MUC7 Proteins)+ ions.

  9. Mortalin is a key regulator of multiple signaling and metabolic pathways pivotal to medullary thyroid carcinoma cell survival and proliferation.

  10. Human mot-1, R126W, or P509S mutants lack mot-2 functions involved in carcinogenesis.

Mouse (Murine) Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. This study demonstred that Mortalin expression in brain astrocytes.

  2. data imply a role for Hspa9 in B lymphopoiesis and Stat5 (show STAT5A Proteins) activation downstream of IL-7 (show IL7 Proteins) signaling

  3. Matrin 3 (show MATR3 Proteins) interacts specifically with the heat shock proteins glucose-regulated protein 78 (show HSPA5 Proteins), GRP75 and glutathione S-transferase (show GSTa2 Proteins) pi isoform 2.

  4. down-regulation of mortalin may potentiate Abeta (show APP Proteins)-mediated mitochondrial fragmentation and dysfunction in AD.

  5. the mortalin/DJ-1 (show PARK7 Proteins) complex guards against mitochondrial oxidative stress and is indispensable for the maintenance of hematopoietic stem cells

  6. Inflammatory response of microglial cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein (show HSP90B1 Proteins) 75/mortalin.

  7. Knockdown of Hspa9 results in a decrease in hematopoietic progenitors resulting in myelodysplastic syndromes.

  8. Data show that RNAi-mediated down-regulation of GRP75 and GRP75-blocking antibodies, both of which inhibited macromolecular endocytosis.

  9. The asymmetric segregation of mortalin in the bipotent cell line and its uniform distribution in a committed, lineage-restricted cell line raises the possibility that it may play a role in cell fate determination

  10. Mortalin imaging was used in normal and cancer cells with quantum dotimmuno-conjugates.

HSPA9 Protein Profile

Protein Summary

This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.

Gene names and symbols associated with HSPA9

  • heat shock 70kDa protein 9 (mortalin) (hspa9-a)
  • heat shock 70kDa protein 9 (mortalin) (hspa9)
  • heat shock 70kDa protein 9 (mortalin) (HSPA9)
  • stress-70 protein, mitochondrial-like (HSPA9)
  • heat shock protein 9 (Hspa9)
  • 74kDa protein
  • Csa protein
  • GRP-75 protein
  • Grp75 protein
  • Hsc74 protein
  • Hsp74 protein
  • Hsp74a protein
  • hspa9 protein
  • Hspa9a protein
  • HSPA9B protein
  • Mortalin protein
  • MOT protein
  • Mot-2 protein
  • Mot2 protein
  • Mthsp70 protein
  • MTHSP75 protein
  • Pbp74 protein

Protein level used designations for HSPA9

heat shock 70kDa protein 9 (mortalin) , heat shock 70kDa protein 9B , Stress-70 protein, mitochondrial-like protein , heat shock 70 kDa protein 9B , stress-70 protein, mitochondrial , GRP-75 , heat shock 70 kDa protein 9 , 75 kDa glucose-regulated protein , stress-70 protein, mitochondrial-like , heat shock 70kD protein 9B , mortalin, perinuclear , mortalin-2 , p66-mortalin , peptide-binding protein 74 , GRP 75 , heat shock 70kDa protein 9B (mortalin-2) , C3H-specific antigen , heat shock protein 9A , heat shock protein cognate 74 , heat shock protein, 74 kDa, A , heat shock protein, A , p66 MOT , PBP74 , heat shock 70kDa protein 9A , mortalin , mtHSP70 , 70 kDa heat shock protein , Heat shock 70 kDa protein 9

GENE ID SPECIES
379314 Xenopus laevis
407910 Xenopus (Silurana) tropicalis
577721 Strongylocentrotus purpuratus
714506 Macaca mulatta
100020208 Monodelphis domestica
100034032 Equus caballus
100173869 Pongo abelii
100406895 Callithrix jacchus
100521183 Sus scrofa
100590864 Nomascus leucogenys
416183 Gallus gallus
3313 Homo sapiens
517535 Bos taurus
474697 Canis lupus familiaris
15526 Mus musculus
291671 Rattus norvegicus
100689405 Cricetulus griseus
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