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Helicase-Like Transcription Factor Proteins (HLTF)

HLTF encodes a member of the SWI/SNF family. Additionally we are shipping HLTF Antibodies (68) and HLTF Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLTF 6596 Q14527
HLTF 20585 Q6PCN7
Rat HLTF HLTF 295568  
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Top HLTF Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

HLTF Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Helicase-Like Transcription Factor (HLTF) Interaction Partners

Human Helicase-Like Transcription Factor (HLTF) interaction partners

  1. HLTF expression is altered in various cancers via two mechanisms: gene silencing through promoter hypermethylation or alternative mRNA splicing, which leads to the expression of truncated proteins that lack DNA repair domains. [review]

  2. HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain.

  3. Findings indicate a mechanism of helicase-like transcription factor HLTF-mediated fork reversal and suggest the requirement for distinct fork remodeling activities in the cell.

  4. Study demonstrates a correlation between HLTF expression level and thyroid neoplastic progression where three truncated forms are detected in thyroid carcinoma.

  5. We were able to provide evidence that methylation of HLTF and especially HPP1 detected in serum is strongly correlated with cell death in CRC using LDH as surrogate marker

  6. Results demonstrate that loss of HLTF function promotes the malignant transformation of intestinal or colonic adenomas to carcinomas by inducing genomic instability.

  7. results delineate a previously unknown USP7 (show USP7 Proteins)-HLTF-PCNA (show PCNA Proteins) molecular network controlling DNA damage response

  8. HLTF can displace a broad spectrum of proteins such as replication protein A (RPA (show RPA1 Proteins)), PCNA (show PCNA Proteins), and replication factor C (RFC (show RFC1 Proteins)), thereby providing the first example for a protein clearing activity at the stalled replication fork.

  9. HLTF and SHPRH suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV rays and methyl methanesulfonate.

  10. results suggest that HLTF is involved in DNA repair and apoptosis in cancer cells, which might represent a target for gene therapies of human cancer

Rabbit Helicase-Like Transcription Factor (HLTF) interaction partners

  1. Prolactin (show PRL Proteins) dependent Jak2 (show JAK2 Proteins) phosphorylation of RUSH.

  2. Splice arrays and RT-PCR showed that although most splice variants in RUSH and ATP11B (show ATP11B Proteins) are conserved in human and rabbit, the RFBP isoform is specific to rabbit.

Mouse (Murine) Helicase-Like Transcription Factor (HLTF) interaction partners

  1. silencing Hltf during heart organogenesis compromised DNA double-strand break repair, and caused aberrant collagen biogenesis altering the structural network that transmits cardiomyocyte force into muscle contraction

  2. Data show a role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain

  3. p11 (show S100A10 Proteins) and AnxA2 (show ANXA2 Proteins) cooperate to create a unique binding pocket, but the optimal binding condition is not achieved without conformational changes associated with target binding. Upon interaction with the SMARCA3 peptide, both Asp60 in p11 (show S100A10 Proteins) and Ser12 in AnxA2 (show ANXA2 Proteins) flip inward toward the peptide-binding groove, forming additional intermolecular hydrogen bonds.

  4. Results demonstrate that loss of HLTF function promotes the malignant transformation of intestinal or colonic adenomas to carcinomas by inducing genomic instability.

HLTF Protein Profile

Protein Summary

This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

Gene names and symbols associated with HLTF

  • helicase-like transcription factor (HLTF)
  • helicase-like transcription factor (hltf)
  • helicase-like transcription factor (Hltf)
  • AF010600 protein
  • BC057116 protein
  • HIP116 protein
  • HIP116A protein
  • HLTF protein
  • HLTF1 protein
  • MGC131155 protein
  • P113 protein
  • RNF80 protein
  • RUSH protein
  • Smarca3 protein
  • Snf2l3 protein
  • wu:fc33f07 protein
  • ZBU1 protein

Protein level used designations for HLTF

helicase-like transcription factor , SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3 , DNA-binding protein/plasminogen activator inhibitor 1 regulator , DNA-binding protein/plasminogen activator inhibitor-1 regulator , RING finger protein 80 , SNF2-like 3 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 , sucrose nonfermenting protein 2-like 3 , sucrose nonfermenting-like 3 , RUSH 1 , RUSH-1 , TNF-response element-binding protein , helicase-like transcription factor-like protein

GENE ID SPECIES
100058775 Equus caballus
324585 Danio rerio
460766 Pan troglodytes
735224 Xenopus laevis
100404714 Callithrix jacchus
100431605 Pongo abelii
100471960 Ailuropoda melanoleuca
100555259 Anolis carolinensis
100580659 Nomascus leucogenys
100617443 Monodelphis domestica
6596 Homo sapiens
100009232 Oryctolagus cuniculus
20585 Mus musculus
295568 Rattus norvegicus
477106 Canis lupus familiaris
539633 Bos taurus
100520979 Sus scrofa
100716292 Cavia porcellus
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